Structure of PDB 6yxx Chain AW Binding Site BS01

Receptor Information
>6yxx Chain AW (length=278) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPRPAPRFAMGHMLPHRSNVGSQFLHTQRHGSRSTWYKKHYFSLRPFAIQ
RHHGTTPRILLDRSLWKSLWITKLQLPDINRWERVVNSRRVTEDRYAFVE
EEGVMHKVNWGLYCERLETELTVTQERLPQHTLLMKAVPSSWKKLDIDIS
VIRGLSLREAMAQCKLSLRKGHQIVFRALEMAQQGAEAKGLDKEHLRVAH
ISCYPGPTDKQIDIRSKGYYAWKTKKSSHLVLTLAEDPEMVLPDRTCLPY
SSLMSMKRAGLSAQPTVIDVPAITADGI
Ligand information
>6yxx Chain AA (length=904) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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....
Receptor-Ligand Complex Structure
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PDB6yxx Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis.
Resolution3.9 Å
Binding residue
(original residue number in PDB)
M1 P2 R3 P6 H12 H16 R17 S18 N19 S22 Q23 F24 L25 Q28 H30 S32 R33 Y37 K38 K39 H40 Y41 R45 F47 Q50 R51 H52 H53 G54 T55 T56 P57 I59 L61 R63 K67 S68 L69 K73 W82 R84 Y96 F98 K143 K144 R153 H200 Y204 R215 W222 T224 K225 V231
Binding residue
(residue number reindexed from 1)
M1 P2 R3 P6 H12 H16 R17 S18 N19 S22 Q23 F24 L25 Q28 H30 S32 R33 Y37 K38 K39 H40 Y41 R45 F47 Q50 R51 H52 H53 G54 T55 T56 P57 I59 L61 R63 K67 S68 L69 K73 W82 R84 Y96 F98 K143 K144 R153 H200 Y204 R215 W222 T224 K225 V231
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6yxx, PDBe:6yxx, PDBj:6yxx
PDBsum6yxx
PubMed32679035
UniProtC9ZSI8

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