Structure of PDB 6gq1 Chain AW Binding Site BS01

Receptor Information

>6gq1 Chain AW (length=37) Species: 559292 (Saccharomyces cerevisiae S288C)

KLRRECSNPTCGAGVFLANHKDRLYCGKCHSVYKVNA

Ligand information

>6gq1 Chain 2 (length=1776)

uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguuccuuuacuacaugguauaacu
gugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaaga
gauguauuuauuagauaaaaaaucaaugucuucggacucuuugaugauuc
auaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaa
auuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuu
caacggguaacggggaauaaggguucgauuccggagagggagccugagaa
acggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccu
aauucagggagguagugacaauaaauaacgauacagggcccauucggguc
uuguaauuggaaugaguacaauguaaauaccuuaacgaggaacaauugga
gggcaagucuggugccagcagccgcgguaauuccagcuccaauagcguau
auuaaaguuguugcaguuaaaaagcucguaguugaacuuugggcccgguu
ggccggucggauuuccaacggggccuuuccuucuggcuaaccuugagucc
uuguggcucuuggcgaaccaggacuuuuacuuugaaaaaauuagaguguu
caaagcaggcguauugcucgaauauauuagcauggaauaauagaauagga
cguuugguucuauuuuguugguuucuaggaccaucguaaugauuaauagg
gacggucgggggcaucaguauucaauugucagaggugaaauucuuggauu
uauugaagacuaacuacugcgaaagcauuugccaaggacguuuucauuaa
ucaagaacgaaaguuaggggaucgaagaugaucagauaccgucguagucu
uaaccauaaacuaugccgacuagggaucgggugguguuuaugacccacuc
ggcaccuuacgagaaaucaaagucuuuggguucuggggggaguauggucg
caaggcugaaacuuaaaggaauugacggaagggcaccaccaggaguggag
ccugcggcuuaauuugacucaacacggggaaacucaccagguccagacac
aauaaggauugacagauugagagcucuuucuugauuuugugggugguggu
gcauggccguucuuaguugguggagugauuugucugcuuaauugcgauaa
cgaacgagaccuuaaccuacuaaauaguggugcuagcauuugcugguuau
ccacuucuuagagggacuaucgguuucaagccgauggaaguuugaggcaa
uaacaggucugugaugcccuuagacguucugggccgcacgcgcgcuacac
ugacggagccagcgagucuaaccuuggccgagaggucuugguaaucuugu
gaaacuccgucgugcuggggauagagcauuguaauuauugcucuucaacg
aggaauuccuaguaagcgcaagucaucagcuugcguugauuacgucccug
cccuuuguacacaccgcccgucgcuaguaccgauugaauggcuuagugag
gccucaggaucugcuuagagaagggggcaacuccaucucagagcggagaa
uuuggacaaacuuggucauuuagaggaacuaaaagucguaacaagguuuc
cguaggugaaccugcggaaggaucau

...<<<<<...[[[[>>>>>[[[..((((((................[[[
.[[[..<<....<<....<<..........>>...>>.>>......{{..
......[[[..{{..{{....[[[..................<.....<<
.<<.......>>.>>......>.........<<<<<..<<....>>..>>
>>>[...((((((......<<<<<<<<<<<....>>>.............
.)))))).....]...<<<<..<<<.....>>>.>>>>....]]]...}}
}}..]]].<<<....<<<....<<<<<<<<.......>>>>>>>>>>>..
....>>>...<<<.<<<<....>>>>....>>>.}}.<<.<<<.......
...>>>.>>...<<<..>>>.....]]]]]].........<<<....<<<
.....>>>..>>>...............<<<<<<<<<<<<<....>>>>>
>>>>>.>>>......<<..<...........>..>>.........<<<<<
((......<<<<.....<<..))>>.......>>>>.>>>>>..))))))
.]]].........[[[{{.......{{...[[[.{{....<<<<<<.<<<
<<............>>>>>.>>>>>>.....<<<<.........<<<...
......>>>.........>>>>....<<<<<.<<.......<<...<...
....>..<<<.....>>>....>>......>>.>>..>>>.........[
[[..((((((((....>>>>>>>>.)))))))).]]].....}}....<<
<<<<.<<...<<<<..<<..<<<<<<.<...<<........>>......>
.>>>>>>..>>.......<<....>>...>>>>..>>.>>>.>>>...]]
]...}}......<<<<<<<...<...<<<<.........>>>>...>>>>
>>>>..........<<<.<<.<<<..<<<<<<<<.<<<...>>>>>>>>>
>>..>>>...<<..}}>>...>>.....>>>.]]].<<<......<<<..
....>>>....>>>..]]]]..<<<<<.<<<<<<<..<<.<<<<<<..<<
<.<<<<.<......<<........>>..........<<<<<.<....<<<
<<........<<.<<<........>>>.>>......>>>>>...<<.<<<
.....<<<<<<....<<<.<<<<......>>...<<<......>>>...>
>.>>>....<<<<..<<..<.<<..<<<<<.<<<<<<....>>>>>>...
>>>>>..>>.>.>>....<<<<<<.....>>>>>>........>>>>...
.>>>.>>>.......>>>>>.....>.>>>>>...>..>>>>.>>>....
.<<<<<<<......<<.....<<..<<<<....>>>>..>>....>>...
....>>>>>>>...........<<<<<<..........>>>>>>......
....>>>>>>....<<<<<<<<.......>>>>>>>>......>>...>>
>>>>>>>>.>>.......<<.<..<<<<.<<....<<<<<<<<.<<<..<
.<<..<...<<<<<<<.<<<<..............>>>>.>>>>>>>...
>..>>.>..>>>.>>>>>>>>...>>.>>>>...>.>>.........<<<
<<<<<<....>>>>>>>>>.......

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6gq1 Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance.
• Resolution: 4.4 Å
• Binding residue (original residue number in PDB): F131 L132 A133 H135 K136 R138 Y140 G142 K143 H145 S146 K149
• Binding residue (residue number reindexed from 1): F16 L17 A18 H20 K21 R23 Y25 G27 K28 H30 S31 K34

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome

External links

• PDB: RCSB:6gq1, PDBe:6gq1, PDBj:6gq1
• PDBsum: 6gq1
• PubMed: 29886014
• UniProt: P05759|RS31_YEAST Ubiquitin-ribosomal protein eS31 fusion protein (Gene Name=RPS31)