Structure of PDB 6zsc Chain AV Binding Site BS01

Receptor Information
>6zsc Chain AV (length=349) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSAYVDSHKWEAREKEHYCLADLASLMDKTFERKLPVSSLTISRLIDNIS
SREEIDHAEYYLYKFRHSPNCWYLRNWTIHTWIRQCLKYDAQDKALYTLV
NKVQYGIFPDNFTFNLLMDSFIKKENYKDALSVVFEVMMQEAFEVPSTQL
LSLYVLFHCLAKKTDFSWEEERNFGASLLLPGLKQKNSVGFSSQLYGYAL
LGKVELQQGLRAVYHNMPLIWKPGYLDRALQVMEKVAASPEDIKLCREAL
DVLGAVLKALTKLVEQLDIEETEQSKLPQYLERFKALHSKLQALKIESEG
LLSLTTQLVKEKLSTCEAEDIATYEQNLQQWHLDLVQLIQREQQQREQA
Ligand information
>6zsc Chain AA (length=924) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auagguuugguccuagccuuucuauuagcucuuaguaagauuacacaugc
aagcauccccguuccagugaguucacccucuaaaucgaucaaaaggaaca
agcaucaagcacgcagcaaugcagcucaaaacgcuuagccuagccacacc
cccacgggaaacagcagugauuaaccuuuagcaauaaacgaaaguuuaac
uaagcuauacuaaccccaggguuggucaauuucgugccagccaccgcggu
cacacgauuaacccaagucaauagaccggcguaaagaguguuuuagauca
caauaaagcuaaaacucaccugaguuguaaaaaacuccaguugacacaaa
auagacuacgaaaguggcuuuaacauaucugaacacacaauagcuaagac
ccaaacugggauuagauaccccacuaugcuuagcccuaaaccucaacagu
ucaacaaaacugcucgccagaacacuacgagccacagcuuaaaacucaaa
ggaccuggcggugcuucauaucccucuagaggagccuguucuguaaucga
uaaaccccgaucaaccucaccaccucuugcucagccuauauaccgccauc
uucagcaaacccugaugaaggcuacaaaguaagcgcaaguacccacguaa
agacguuaggucaagguguagcccaugagguggcaagaaaugggcuacau
uuucuaccccagaaacgauagcccuuaugaauaagggucgaagguggauu
uagcaguaaacuaagaguagagugcuuaguugaacagggcccugaagcgc
guacacaccgcccgucacccuccucaaguauacuucaaaggacuuaacua
aaaccccuacgcauuuauauagaggagacaagucguaacaugguaagugu
acuggaaagugcacuuggacgaac
..((((..<<<<<<.)))).<<<<<<.<...<<<<<<<<..<.<<<.<<<
..<......>......<<........<<<.<..<<..>>.>..>>>...<
<<<....<<...<<<....>>>..>>......>>>>.<<...>>.>>.<<
<....>>>.....>>>>>>>........<<<....<<<......>>>..>
>>..>>.>>>>>>.....<<<<<<<<.....(((.....((.>>>))...
....)))..>>>>>...>.>>>>>>..<<<((.....<<<<..<<<<...
...<<<<<<......<<<.<<<.<<<......>>>..>>>.>>>......
......<<<....>>>>>>>>>.....>>>>...>>>>....<<<<<<..
.<<...<<<<.<.....>.>>>>...>>>>>>>>..........<.<<<<
<..))..>>>>>.>.>>>.<<.......<<<<....>>>>.....>>..>
>>>>><<<<<.<<<<<<<...<<<.<<<<<..<<<<<<<<<<.....<<.
.......>>..........<<<<<<<.......<<.<<<..<<<<<<.<.
....<<..<<<<<.....>>>.......>>..>>.....<<<....>>>.
....>...>>>...>>>>>>>>....>>>>>>>..>>.>>>>>>>>....
.<<<<.....>>>>.<....<<<<<<<....>>>>>>>....>.....>>
>>>.....<<<<<<<.........>>>>>>>.....>>>...>>>>>>>>
>>.>>....<..<<.<...<<<<<<..<<<<<..<...<<<..<<.....
>>...>>>....>..>>>>>.>>>>>>....>.>>...>.....<<<<<<
<<<....>>>>>>>>>........
Receptor-Ligand Complex Structure
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PDB6zsc Structural basis of mitochondrial translation.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		K64 L65 P66 V67 S68 W102 Y103 R105 R392
Binding residue
(residue number reindexed from 1)		K34 L35 P36 V37 S38 W72 Y73 R75 R341
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0097177 mitochondrial ribosome binding
Biological Process
GO:0006417 regulation of translation
GO:0008283 cell population proliferation
GO:0032543 mitochondrial translation
GO:0070131 positive regulation of mitochondrial translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6zsc, PDBe:6zsc, PDBj:6zsc
PDBsum6zsc
PubMed32812867
UniProtQ92552|RT27_HUMAN Small ribosomal subunit protein mS27 (Gene Name=MRPS27)

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