Structure of PDB 6z1p Chain AV Binding Site BS01

Receptor Information

>6z1p Chain AV (length=129) Species: 312017 (Tetrahymena thermophila SB210)

YKKIRDVPTEEFIAVQKPESQSKYEHVKIEIKEFDFQNKPDRTLGDQKPV
PVSPLLGPYKVENPKLGEKKYKWCSCGLSTSQPFCDGKHKGTAFLPYKFT
VEEATQYMNLCGCKFTTNPPFCDNKTCKC

Ligand information

>6z1p Chain Ab (length=2237)

uaguaaauuucaauaaguuuuugaaauugaaaaauagagaucuaccucua
aaacuuguaaaguuuaaauucaauagaaaacaguaccgcgagggaaaggu
gaaaagauuuuauaauaucuuaaaagaaccugaaauuuagugcuaaauac
aguuaaagcuuuauuguuuuaacguaccuuuugcauaaugggcuagcgag
uuuauauaauuagcgaguaauuuaaauuuuauaaaauuacgaaucgauag
aauaaauaguuaauuauauaagacccgaagcuaagugaucuaauuaugau
uagauuaaggguauuuauaccugaggaucgaacucuuaaauguugcaaaa
uuuugggauaaauuguaauuaggggugaaaggcuuaucaaacuuaguuau
agcugguuuuccacgaaaccuauuuaaguaggguguuauuuuuuauaaua
auuagguuuaaauaacuauaucuauaauuaauuuguuaauuauaaaauua
guauauaauaauuaguuauuauuagauaauaaccagacuauuagcgcuaa
gguuuauagucaagagagaaacagcucagauuaaacaauaaggucuuuaa
aaauaaauaauuauggagauuauuuuuguuaauacuaauaagauguaggc
uuggaagcagccaucauuuuaaaaaagcguaaaagcuuaauauuagauaa
auuaauguuaaaaauuaauugauacuuaaauaaucauagaugaagagaga
auaauuuuuauuuaccgaauugauaaaucgaaagaugguaguggaacguu
uuguauaaaaaaauaaaauugugaaauuuuauauuuuaucaauauugaua
augcuagcaugaguaguagacauaaugugagaaucauuaucgccugauau
acaaggguuacuaaauuugauaaucuuauuuaguguaagucgauuucuaa
gauauaaaaguauauuguuaucaaugaauauaaaauauaaaauaucuaau
aaacuacuuuuuauauuauauaaaauuuuuuauaauauaggugguuuagu
gacuggaaauguuuauauuuuauuaaaucguacuaacucuaacacaagug
uuuaaguagaauauauaauggcgaaggaguaaaaaguauugaaggaacua
ggcaaaauaacccuguaacuuugggagaaagggggcuuuuaagcaacuga
aaagagagaguagcgacuguuuaauaaaaacauaagauuuugcaaaauuu
aaauaugauguauaaaaucugacaccugcccggugcugcaaggugaaucu
auuuuaguuaacgcugaaauauuaaaccccaguaaacggcggccguaacc
cugacgguccuaagguagcaaaauuccuuggcggguaaguuccguccugc
augaaugguguaacgacugcucugcugucuccaauacuugcucuacgaaa
uugaacuuuccgugaagaugcggcaauauuacaacuagacgggaagaccc
uaugcaccuuuacuguuaucuguaauuaauuuaauuacauauaaauaaaa
uaaauuuuaauuauuuuuguuauugaaagacaguuugacuggggcggucu
ccuccuaaaaaguaacggaggaguauaauaauuugggguaucuuauuuua
auugagaucaauauuagaaugaauauacuaaauuugauuagaguacaaac
aaguauucuaaggauauaugucugucauauugacccgauauaauuuagua
gaaaauauaucgaucaacgaauaaaagguacgcuagggauaacaggcuua
uggguuuugagaguucuuauuaauaaacccguuuggcaccucgaugucgg
cucaucacauccugaugguggacaaucuaucaaggguccggcuguucgcc
gguuaaagugguacgugagcuggguuuaaaacgucgugagacaguuuggu
cccuaucuguuguaauuacaagaaaauaaauaagaauuaacuuuaguacg
agaggacuaggaaaauuuaaucacugguuugaaaauuacuuuaauaaaua
aaaguacgguuuuuaagcuaaauuaaacaagauaauugcugaauucuaua
uaagcaagaaucuaacuuauauuauuuucuaauaaacuuuuuaaagacua
uauuauuuaaguauauuuauuaagagucauuauaacuaauaaauauaaau
auacuaaauguuuaauaaucacuacaguuuaguuuuu

.....<<<<<<<<.......>>>>>>>>......<<<<<..((((>>>>>
...................................<<....>>.......
..................................................
.<<<<<<<<......>>>>>>>>...<.<........>.>.<<<<<<...
.<<<<<<<<<<<<...<<<..................>>>...<<....>
>........>>>>>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<
..<<<...<<<<<<..>>>>>>....>>>...<<<..<<<<........>
>>>.>>>....>>>>>>>>>...<<<.....>>>......>>>>>>....
..>.>>..<<<<<<....<<<<<....>>>>><<<<<<<<....<<<<<<
<<<.....<..<<.<<<<..<..<<<<<<<<....>>>>>>>>..>..>>
>>..>>.>.....>>>>>>>>>..>>>>>>.>>..<<<<<<.<<<.....
.>>>.>>>>>>....<<<......>>>...<<<..<<<...<<<(((...
<<<<<<<..........<<<<<<<<....<<...<<<<<<..<<<..<<<
<.......>>>>..>>>.......<<<<......>>>>..>>>>>>...<
<<<<...........>>>>>..>>...>>>>>>>>...........))).
......>>>>>>>>>>...>>>.>>><<<....>>>....>>>>>><<..
<<<...<<....<<<<<<<<....>>>>>>>>...>>..>>>...>>...
..>>>>>><......<<....<<<<<<.......>>>>>><<<<....<.
<<..<....<<<<<<.............>>>>>>.......<<<.<<...
<<<....<<.....>>...>>>...>>....<<<<<<<<<<...<<...<
<<<<<<<.....<<<<<<<<....[[.[[.>>>>>>>>..>>>>>>>>..
>>.........>>>>>>>>>>.....>>>....>....<<......>>.>
>.>..<<<.....>>>...>>>>..<<<<<...<<<<<<<..<<......
..........<<<<...............>>>>.<<......>>......
......<<<<<<<<<..<<<.........>>>..<<<<<<<.....<<..
....>>.......>>>>>>>.<<<<<.<<<..<<<<<<...<<<.....<
<<<<<<<<....>>>>>>>>>....>>>.>>>>..>>>>><<<<<<....
...>>>>>>........<...........<<<<<.......>>>>>....
.>....>>>>>..>>.>>>>>>>.....>>..>>>>>>>>>>>>>>....
.>.....<.<<<........>>>.>..<<<<<<<<.<<<.<<<.....<<
<<.<.<<<<..<<<<...<<.<<<<<<<<<<.>>>>>.<.<<<<......
..........>>>>.>..>>>>>.>>....>>>>..<<<<.....>>>><
<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.....
..>>>>>>....<<<...(((>>>...>>>>>>>...<<<<<<<<<....
..>>>>>>>>>.<<<....>>>.>>))).......<<<<<<.<<<..)))
)..>>>>>>>>>.............>>>>...>>>>>.......<<<<..
.<<<<<<...<<.......>>...>>>>>>....>>>.>.......<.<<
<.<<<<<<..<<<<<<<<........>>>>>>..>>.<<<<<.....>>>
>>.....>>>>>..>...>>>..>....<<<<<<<....>>>.>>>>...
>>>..>>>>>>>>>>>....<<<<<<<<.<<<<<.<<<..<<<.......
........>>>..>>><<<<<....<<<..<<<<<<<<<<<<...]]]].
>>>>>>..>>>>>>..>>>..>>>>>...<<<...<<<<<..........
..>>>>>...>>>..>>>>>..>>>>>>>>...<<<<.<..<<.......
>>..>....<<<<<<<<<<<.........<.......>......>>>>>>
>>>>>....>>>>........................

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6z1p Ciliate mitoribosome illuminates evolutionary steps of mitochondrial translation.
• Resolution: 3.7 Å
• Binding residue (original residue number in PDB): K23 K90 K91 K93 K111 P117 K119
• Binding residue (residue number reindexed from 1): K2 K69 K70 K72 K90 P96 K98

Gene Ontology

Molecular Function

• GO:0046872 metal ion binding
• GO:0051537 2 iron, 2 sulfur cluster binding

Biological Process

• GO:0106034 protein maturation by [2Fe-2S] cluster transfer

Cellular Component

• GO:0005737 cytoplasm
• GO:0005739 mitochondrion
• GO:0043231 intracellular membrane-bounded organelle

External links

• PDB: RCSB:6z1p, PDBe:6z1p, PDBj:6z1p
• PDBsum: 6z1p
• PubMed: 32553108
• UniProt: Q22HE3