Structure of PDB 6xu8 Chain AU Binding Site BS01

Receptor Information
>6xu8 Chain AU (length=102) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVHRIRITLTSRNVRSLENVCRDLINGAKNQNLRVKGPVRMPTKTLRITT
RKTPCGEGSKTWDRFQMRIHKRIIDLHSPSEIVKKITSINIEPGVEVEVT
IA
Ligand information
>6xu8 Chain B2 (length=1936) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auucugguugauccugccaguaguuauaugcuugucucaaagauuaagcc
augcaugucuaaguacacacgaauuaaaagugaaaccgcaaaaggcucau
uauaucaguuaugguuccuuagaucguuaacaguuacuuggauaacugug
guaauucuagagcuaauacaugcaauuaaaacaugaaccuuaugggacgu
gugcuuuuauuaggcuaaaaccaagcgaucgcaagaucguuauauugguu
gaacucuagauaacaugcagaucguauggucuuguaccgacgacagaucu
uucaaaugucugcccuaucaacuuuugaugguaguaucuaggacuaccau
gguugcaacggguaacggggaaucaggguucgauuccggagagggagccu
gagaaacggcuaccacaucuaaggaaggcagcaggcgcguaaauuaccca
cucccagcucggggagguagugacgaaaaauaacaauacaggacucauau
ccgaggcccuguaauuggaaugaguacacuuuaaauccuuuaacaaggac
caauuggagggcaagucuggugccagcagccgcgguaauuccagcuccaa
uagcguauauuaaaguuguugcgguuaaaacguucguaguugaacuugug
cuucauacggguaguauacuauaccuuuauguauguaagcguauuaccgg
uggaguucuuauaugugaucauauguuccuccuauuuaaaaaccugcauu
agugcucuuaaacgaguguuauugugggccgguacuauuacuuugaacaa
auuagagugcuuaaagcaggcuucaaaugccugaauauucugugcauggg
auaaugaaauaagaccucuguucugcuuucauugguuuucagaucaagag
guaaugauuaauagaagcaguuugggggcauuaguauuacgacgcgagag
gugaaauucuuggaccgucguaagacuaacuuaagcgaaagcauuugcca
aagauguuuucauuaaucaagaacgaaaguuagagguucgaaggcgauca
gauaccgcccuaguucuaaccauaaacgaugccagcuagcaauugggugu
agcuacuuuuauggcucucucagucgcuuccgggaaaccaaagcuuuuug
ggcuccgggggaaguaugguugcaaagcugaaacuuaaaggaauugacgg
aagggcaccaccaggaguggagccugcggcuuaauuugacucaacacggg
aaaacuuaccaggucgaacauaaguguguaagacagauugauagcucuuu
cucgaaucuaugggugguggugcauggccguucuuaguucguggagugau
uugucugguuaauuccgauaacgaacgagacucaaauauauuaaauagau
aucuucaggauuauggugcugaagcuuauguagccuucauuauuguguuu
gaauguguuuauguaaguggagccguaccuguugguuugucccauuauaa
ggacacuagcuucuuaaauggacaaauugcgucuagcaauaaugagauug
agcaauaacaggucugugaugcccuuagauguccugggcugcacgcgcgc
uacaaugaaaguaucaacguguauuuccuagaccgagagguccggguaaa
ccgcugaaccacuuucaugcuugggauugugaacugaaacuguucacgau
gaacuuggaauucccaguaagugugagucauuaacucgcauugauuacgu
cccugcccuuuguacacaccgcccgucgcuacuaccgauugaauuauuua
gugaggucuccggacgugaucacugugacgccuugcguguuacgguuguu
ucgcaaaaguugaccgaacuugauuauuuagaggaaguaaaagucguaac
aagguuuccguaggugaaccugcggaaggaucauua
...<<<<<.{.((((>>>>><<<<.<<<<<<...<.<<..<......<<<
.<<<..<<....<<....<<.........>>...>>.>>......<<...
.....<<<.<<<..<<....<<<<..............<<.....<<.<<
<.....>>>.>>......>>...........<<<<............>>>
>.<<..<<<<<.....(((...((..<<<<....>>>>........<...
.....>..>>>>>...>>...<...................>....>>>>
...>>>>>.>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>
>>>......>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<..
........>>>.>>.<.<<....>>.>...>>>>>>.........<<<..
..<<<.....>>>..>>>..>...>>.>.....<.<<<<<...<<<....
..>>>....>>>>..>.>.....<<.................>>......
...<<<<<((......<<<<.....<<..))>>.......>>>>.>>>>>
..>>>>>>>>>>.........<<<[[.....<<<<...<<<.<<.....<
<<<...<<......................>>....>>>>......<<..
..................................................
..............................>>....<<<<<<.<<.....
..<<...<.......>..<<<.......>>>....>>.......>>.>>.
.>>>>..........................))...)))...........
.......>>....<<<<..<.<<...<<<<..<<..<<<<<<<<...<<<
......>>>......>>>>>>>.>.>>.......<<....>>...>>>>.
..>>>.>.>>>...>>>...>>>>....<<<<<<<...<...<<<<.<..
...>.>>>>...>>>>>>>>..........<<<.<<.<<<.<<<<<<...
.<<<........>>>...>>>>>>.>>>...<<..]]>>...>>......
>>>.>>>.<<<......<<<......>>>....>>>..)))).}<<....
<<<<<<<..<<..<<<<<.<<<<.<<<<<<......<<........>>..
........<<<<......................<<<........>>>..
...............<<.<<<...<.<<<<<.....<<<.<.........
.....................>.>>>....<<<<..<<..<.<.......
.<.........<..<...................................
.......................>..>.......>...<<<<........
>>>>..........>.>.>>............................>>
>>.....>>.>>>.....>.>>>>>........>>>>...>>.>>>>.>>
>.>...<<<<<<..............<<<.<<<<....>>>>.>>>....
..........>>>>>>.........<<.....<..........>....>>
.........>>>>>.....<<<<<<<<.......>>>>>>>>......>>
...>>>>>>>....>>....<..<<.<..<<<<.<<....<<<<.<<<.<
<<..<<<<..<....<<<<.<<....<<<.........>>>.....>>..
>>>>....>..>>>>..>>>.>>>.>>>>...>>.>>>>...>.>>...>
.....<<<<<<<<<....>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6xu8 Ribosome heterogeneity in Drosophila melanogaster gonads through paralog-switching.
Resolution3.0 Å
Binding residue
(original residue number in PDB)
V19 R23 R32 E35 R51 K53 P55 V56 R57 M58 P59 T60 T66 T67 R68 P71 C72 G73 E74 S76 K77 W79 R81 R85 H87 R89 H94
Binding residue
(residue number reindexed from 1)
V2 R6 R15 E18 R34 K36 P38 V39 R40 M41 P42 T43 T49 T50 R51 P54 C55 G56 E57 S59 K60 W62 R64 R68 H70 R72 H77
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit

View graph for
Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6xu8, PDBe:6xu8, PDBj:6xu8
PDBsum6xu8
PubMed34283226
UniProtP55828|RS20_DROME Small ribosomal subunit protein uS10 (Gene Name=RpS20)

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