Structure of PDB 8bqs Chain AT Binding Site BS01

Receptor Information

>8bqs Chain AT (length=161) Species: 312017 (Tetrahymena thermophila SB210)

RVDYIVTPINAVVSWARQGSFWPLTFGLACCAVEMMHATVSRYDFDRFGV
IFRATPRQADLILVAGTLTNKMAPGLRRLYEQTLDPKWVLSMGSCANGGG
YYHYSYSVVRGCNRIIPVDIYVPGCPPTAEALMFGVLQLQKSLYRQINEG
EKKYNKKDLTY

Ligand information

• Ligand ID: SF4
• InChI: InChI=1S/4Fe.4S
• InChIKey: LJBDFODJNLIPKO-UHFFFAOYSA-N
• SMILES:
  OpenEye OEToolkits 2.0.7: [S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
  CACTVS 3.385: S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
• Formula: Fe4 S4
• Name: IRON/SULFUR CLUSTER
• PDB chain: 8bqs Chain AT Residue 201

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8bqs Structural basis of mitochondrial membrane bending by I-II-III2-IV2 supercomplex
• Resolution: 2.9 Å
• Binding residue (original residue number in PDB): C31 C32 G94 S95 C96 C126 P127
• Binding residue (residue number reindexed from 1): C30 C31 G93 S94 C95 C125 P126
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 1.6.5.3: Transferred entry: 7.1.1.2.

Gene Ontology

Molecular Function

• GO:0008137 NADH dehydrogenase (ubiquinone) activity
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding
• GO:0048038 quinone binding
• GO:0051536 iron-sulfur cluster binding
• GO:0051539 4 iron, 4 sulfur cluster binding

Biological Process

• GO:0009060 aerobic respiration
• GO:0015990 electron transport coupled proton transport

Cellular Component

• GO:0005739 mitochondrion

External links

• PDB: RCSB:8bqs, PDBe:8bqs, PDBj:8bqs
• PDBsum: 8bqs
• UniProt: Q951B4