Structure of PDB 6gq1 Chain AT Binding Site BS01

Receptor Information
>6gq1 Chain AT (length=53) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ENVWFSHPRRYGKGSRQCRVCSSHTGLIRKYGLNICRQCFREKANDIGFN
KFR
Ligand information
>6gq1 Chain 2 (length=1776) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguuccuuuacuacaugguauaacu
gugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaaga
gauguauuuauuagauaaaaaaucaaugucuucggacucuuugaugauuc
auaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaa
auuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuu
caacggguaacggggaauaaggguucgauuccggagagggagccugagaa
acggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccu
aauucagggagguagugacaauaaauaacgauacagggcccauucggguc
uuguaauuggaaugaguacaauguaaauaccuuaacgaggaacaauugga
gggcaagucuggugccagcagccgcgguaauuccagcuccaauagcguau
auuaaaguuguugcaguuaaaaagcucguaguugaacuuugggcccgguu
ggccggucggauuuccaacggggccuuuccuucuggcuaaccuugagucc
uuguggcucuuggcgaaccaggacuuuuacuuugaaaaaauuagaguguu
caaagcaggcguauugcucgaauauauuagcauggaauaauagaauagga
cguuugguucuauuuuguugguuucuaggaccaucguaaugauuaauagg
gacggucgggggcaucaguauucaauugucagaggugaaauucuuggauu
uauugaagacuaacuacugcgaaagcauuugccaaggacguuuucauuaa
ucaagaacgaaaguuaggggaucgaagaugaucagauaccgucguagucu
uaaccauaaacuaugccgacuagggaucgggugguguuuaugacccacuc
ggcaccuuacgagaaaucaaagucuuuggguucuggggggaguauggucg
caaggcugaaacuuaaaggaauugacggaagggcaccaccaggaguggag
ccugcggcuuaauuugacucaacacggggaaacucaccagguccagacac
aauaaggauugacagauugagagcucuuucuugauuuugugggugguggu
gcauggccguucuuaguugguggagugauuugucugcuuaauugcgauaa
cgaacgagaccuuaaccuacuaaauaguggugcuagcauuugcugguuau
ccacuucuuagagggacuaucgguuucaagccgauggaaguuugaggcaa
uaacaggucugugaugcccuuagacguucugggccgcacgcgcgcuacac
ugacggagccagcgagucuaaccuuggccgagaggucuugguaaucuugu
gaaacuccgucgugcuggggauagagcauuguaauuauugcucuucaacg
aggaauuccuaguaagcgcaagucaucagcuugcguugauuacgucccug
cccuuuguacacaccgcccgucgcuaguaccgauugaauggcuuagugag
gccucaggaucugcuuagagaagggggcaacuccaucucagagcggagaa
uuuggacaaacuuggucauuuagaggaacuaaaagucguaacaagguuuc
cguaggugaaccugcggaaggaucau
...<<<<<...[[[[>>>>>[[[..((((((................[[[
.[[[..<<....<<....<<..........>>...>>.>>......{{..
......[[[..{{..{{....[[[..................<.....<<
.<<.......>>.>>......>.........<<<<<..<<....>>..>>
>>>[...((((((......<<<<<<<<<<<....>>>.............
.)))))).....]...<<<<..<<<.....>>>.>>>>....]]]...}}
}}..]]].<<<....<<<....<<<<<<<<.......>>>>>>>>>>>..
....>>>...<<<.<<<<....>>>>....>>>.}}.<<.<<<.......
...>>>.>>...<<<..>>>.....]]]]]].........<<<....<<<
.....>>>..>>>...............<<<<<<<<<<<<<....>>>>>
>>>>>.>>>......<<..<...........>..>>.........<<<<<
((......<<<<.....<<..))>>.......>>>>.>>>>>..))))))
.]]].........[[[{{.......{{...[[[.{{....<<<<<<.<<<
<<............>>>>>.>>>>>>.....<<<<.........<<<...
......>>>.........>>>>....<<<<<.<<.......<<...<...
....>..<<<.....>>>....>>......>>.>>..>>>.........[
[[..((((((((....>>>>>>>>.)))))))).]]].....}}....<<
<<<<.<<...<<<<..<<..<<<<<<.<...<<........>>......>
.>>>>>>..>>.......<<....>>...>>>>..>>.>>>.>>>...]]
]...}}......<<<<<<<...<...<<<<.........>>>>...>>>>
>>>>..........<<<.<<.<<<..<<<<<<<<.<<<...>>>>>>>>>
>>..>>>...<<..}}>>...>>.....>>>.]]].<<<......<<<..
....>>>....>>>..]]]]..<<<<<.<<<<<<<..<<.<<<<<<..<<
<.<<<<.<......<<........>>..........<<<<<.<....<<<
<<........<<.<<<........>>>.>>......>>>>>...<<.<<<
.....<<<<<<....<<<.<<<<......>>...<<<......>>>...>
>.>>>....<<<<..<<..<.<<..<<<<<.<<<<<<....>>>>>>...
>>>>>..>>.>.>>....<<<<<<.....>>>>>>........>>>>...
.>>>.>>>.......>>>>>.....>.>>>>>...>..>>>>.>>>....
.<<<<<<<......<<.....<<..<<<<....>>>>..>>....>>...
....>>>>>>>...........<<<<<<..........>>>>>>......
....>>>>>>....<<<<<<<<.......>>>>>>>>......>>...>>
>>>>>>>>.>>.......<<.<..<<<<.<<....<<<<<<<<.<<<..<
.<<..<...<<<<<<<.<<<<..............>>>>.>>>>>>>...
>..>>.>..>>>.>>>>>>>>...>>.>>>>...>.>>.........<<<
<<<<<<....>>>>>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6gq1 Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance.
Resolution4.4 Å
Binding residue
(original residue number in PDB)
W7 F8 S9 H10 P11 R13 Y14 G15 K16 G17 R19 C24 H27 T28 G29 R32 K33 Y34 C39 R40 Q41 C42 F55 R56
Binding residue
(residue number reindexed from 1)
W4 F5 S6 H7 P8 R10 Y11 G12 K13 G14 R16 C21 H24 T25 G26 R29 K30 Y31 C36 R37 Q38 C39 F52 R53
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6gq1, PDBe:6gq1, PDBj:6gq1
PDBsum6gq1
PubMed29886014
UniProtP41057|RS29A_YEAST Small ribosomal subunit protein uS14A (Gene Name=RPS29A)

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