Structure of PDB 8hl5 Chain AS9P Binding Site BS01

Receptor Information
>8hl5 Chain AS9P (length=136) Species: 330779 (Sulfolobus acidocaldarius DSM 639) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QAEQNFMITYARRKSARASCYIKPGNGKVFVNDIPIEIIPIEVVRYKIME
PLVLAGDKITSSIEARIYTQGGGIMGQADAARMALARALVKFTNSKELVE
IYKSYDRTMLAGDPRQTESEKWMRYSARRWRQKAYR
Ligand information
>8hl5 Chain A16S (length=1492) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auuccgguugauccugccggacccgaccgcuaucgggguagggauaagcc
augggagucuuacacucccggguaagggaguguggcggacggcugaguaa
cacguggcuaaccuacccucgggacggggauaaccccgggaaacugggga
uaauccccgauagggaaggaguccuggaaugguuccuucccuaaagggcu
auaggcuauuucccguuuguagccgcccgaggauggggcuacggcccauc
aggcugucggugggguaaaggcccaccgaaccuauaacggguaggggccg
uggaagcgggagccuccaguugggcacugagacaagggcccaggcccuac
ggggcgcaccaggcgcgaaacguccccaaugcgcgaaagcgugagggcgc
uaccccgagugccuccgcaggaggcuuuuccccgcucuaaaaaggcgggg
gaauaagcggggggcaagucuggugucagccgccgcgguaauaccagcuc
cgcgaguggucggggugauuacugggccuaaagcgccuguagccggccca
ccaagucgccccuuaaaguccccggcucaaccggggaacugggggcgaua
cuggugggcuagggggcgggagaggcgggggguacucccggaguaggggc
gaaauccuuagauaccgggaggaccaccaguggcggaagcgccccgcuag
aacgcgcccgacggugagaggcgaaagccggggcagcaaacgggauuaga
uaccccgguagucccggcuguaaacgaugcgggcuaggugucgaguaggc
uuagagccuacucggugccgcagggaagccguuaagcccgccgccugggg
aguacggucgcaagacugaaacuuaaaggaauuggcgggggagcaccaca
agggguggaaccugcggcucaauuggagucaacgccuggaaucuuaccgg
gggagaccgcaguaugacggccaggcuaacgaccuugccugacucgcgga
gaggaggugcauggccgucgccagcucguguugugaaauguccgguuaag
uccggcaacgagcgagacccccaccccuaguugguauucuggacuccggu
ccagaaccacacuagggggacugccggcguaagccggaggaaggaggggg
ccacggcaggucagcaugccccgaaacucccgggccgcacgcggguuaca
auggcagggacaacgggaugcuaccucaaagggggagccaauccuuaaac
ccugccgcaguugggaucgagggcugaaacccgcccucgugaacgaggaa
ucccuaguaaccgcgggucaacaacccgcggugaauacgucccugcuccu
ugcacacaccgcccgucgcuccacccgagcgagaaaggggugaggucccu
ugcgauaagugggggaucgaacuccuuucccgcgaggggggagaagucgu
aacaagguagccguaggggaaccugcggcuggaucaccucau
...<<<<....((((.>>>>.<<<<<<<<......<<<.<<......<<<
.<<<..<<<...<<<<<<<......>>>>>>>.>>>......<<......
..<<<<<<...<<...<<<<<<<.<<<<<....<<<<<......>>>>>.
....>>>>>...<<<<<<<<<.<<......>>>>>>>>>>>....<.<<<
<<<<<..........>>>>>>>>>.>>>>>>>..>>.>>>>>>.<<<...
.<<....<<<<<<<.......>>>>>>>..>>......>>>..<<<<<<<
<....>>>>...>>>>.>>.<<<<<............>>>>>.<<<<...
.>>>>...>>>>>>.........<<<....<<<<....>>>>..>>>..>
>..>>>....<<<<<<...>>>>>>...<<<<<<<.........>>>>>>
>.....<<<<<((......<<<<.....<<..))>>.......>>>>.>>
>>>...>>>>>>>>..........<<<((.....<<<<...<<<.<<<<<
<<.<<<<<<<<<......<<<<<<<.....>>>>>>>....>>>>>>>..
>>>>>>>>>...<<<<<<.....<<<<<<<<<..<<<<<<<....<<<..
....>>>.......>>>>>>>..>>.......<<....>>.>>>>>>>..
..>>>.>>>...>>>...>>>>...<<<<<<<...<<...<<<<......
...>>>>...>>>>>>>>>.........<<<<<<..<<<<<<<<<<<<<<
.....>>>>>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<.
.....<<<<....>>>>....>>>..))))..<<<<<.<<<<<<<..<<.
<<<<<..<<<<<<<<<........<<........>>..........<<<<
<.<...<<<<<.......<<<.<<<.......>>>.>>>....>.>>>>.
..<<.<<<..<<<<<<<<.....<<<<<<.<<....>>...<<<<.....
.>>>>..>>>>>>....<<<<<.<<<<<<<...<..<<.<<<<<....>>
>>>.>>>....>>>>>>>.....<<<<<....>>>>>........>>>>>
.....>>.>>>...>>>>>>>>.....>>>>>>......>>>>>>>>.>.
..<<<<<<<.....<<...<<..<<<.....>>>..>>....>>.....>
>>>>>>...........<<<<<<<........>>>>>>>...........
>>>>>....<<<<<<<.........>>>>>>>......>>...>>>>>>>
>>>.>>....<..<<.<.<<<<.<<<..<<<.<<<<<<<<<..<<<<<<<
<<<.....>>>>>>>>>>..>>>>>>>>>.>>>..>>>.>>>>..>.>>.
..>.....<<<<<<<<<....>>>>>>>>>............
Receptor-Ligand Complex Structure
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PDB8hl5 Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
Resolution5.72 Å
Binding residue
(original residue number in PDB)
Q3 A4 Q6 F8 I10 Y12 R14 K16 S17 Y23 K25 R68 G73 G74 G75 I76 M77 G78 Q79 R109 R117 Q118 T119 E120 S121 E122 K123 W124 M125 R126 Y127 S128 A129 R130 R131 W132 R133 Q134 Y137 R138
Binding residue
(residue number reindexed from 1)
Q1 A2 Q4 F6 I8 Y10 R12 K14 S15 Y21 K23 R66 G71 G72 G73 I74 M75 G76 Q77 R107 R115 Q116 T117 E118 S119 E120 K121 W122 M123 R124 Y125 S126 A127 R128 R129 W130 R131 Q132 Y135 R136
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8hl5, PDBe:8hl5, PDBj:8hl5
PDBsum8hl5
PubMed37604686
UniProtP39468|RS9_SULAC Small ribosomal subunit protein uS9 (Gene Name=rps9)

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