Structure of PDB 8hl5 Chain AS8P Binding Site BS01

Receptor Information
>8hl5 Chain AS8P (length=130) Species: 330779 (Sulfolobus acidocaldarius DSM 639) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
INPLANALATLYNNEMRRNKQALITPASKLIISVLRVMQKEGYIGEFEYI
DDGRAGKIIVQLLGRINKCGPISPRYPLDYNGLLRLPDYIRKYLPSKEIG
IIIISTPKGVMSHRDGIREKIGGVTLGYVY
Ligand information
>8hl5 Chain A16S (length=1492) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auuccgguugauccugccggacccgaccgcuaucgggguagggauaagcc
augggagucuuacacucccggguaagggaguguggcggacggcugaguaa
cacguggcuaaccuacccucgggacggggauaaccccgggaaacugggga
uaauccccgauagggaaggaguccuggaaugguuccuucccuaaagggcu
auaggcuauuucccguuuguagccgcccgaggauggggcuacggcccauc
aggcugucggugggguaaaggcccaccgaaccuauaacggguaggggccg
uggaagcgggagccuccaguugggcacugagacaagggcccaggcccuac
ggggcgcaccaggcgcgaaacguccccaaugcgcgaaagcgugagggcgc
uaccccgagugccuccgcaggaggcuuuuccccgcucuaaaaaggcgggg
gaauaagcggggggcaagucuggugucagccgccgcgguaauaccagcuc
cgcgaguggucggggugauuacugggccuaaagcgccuguagccggccca
ccaagucgccccuuaaaguccccggcucaaccggggaacugggggcgaua
cuggugggcuagggggcgggagaggcgggggguacucccggaguaggggc
gaaauccuuagauaccgggaggaccaccaguggcggaagcgccccgcuag
aacgcgcccgacggugagaggcgaaagccggggcagcaaacgggauuaga
uaccccgguagucccggcuguaaacgaugcgggcuaggugucgaguaggc
uuagagccuacucggugccgcagggaagccguuaagcccgccgccugggg
aguacggucgcaagacugaaacuuaaaggaauuggcgggggagcaccaca
agggguggaaccugcggcucaauuggagucaacgccuggaaucuuaccgg
gggagaccgcaguaugacggccaggcuaacgaccuugccugacucgcgga
gaggaggugcauggccgucgccagcucguguugugaaauguccgguuaag
uccggcaacgagcgagacccccaccccuaguugguauucuggacuccggu
ccagaaccacacuagggggacugccggcguaagccggaggaaggaggggg
ccacggcaggucagcaugccccgaaacucccgggccgcacgcggguuaca
auggcagggacaacgggaugcuaccucaaagggggagccaauccuuaaac
ccugccgcaguugggaucgagggcugaaacccgcccucgugaacgaggaa
ucccuaguaaccgcgggucaacaacccgcggugaauacgucccugcuccu
ugcacacaccgcccgucgcuccacccgagcgagaaaggggugaggucccu
ugcgauaagugggggaucgaacuccuuucccgcgaggggggagaagucgu
aacaagguagccguaggggaaccugcggcuggaucaccucau
...<<<<....((((.>>>>.<<<<<<<<......<<<.<<......<<<
.<<<..<<<...<<<<<<<......>>>>>>>.>>>......<<......
..<<<<<<...<<...<<<<<<<.<<<<<....<<<<<......>>>>>.
....>>>>>...<<<<<<<<<.<<......>>>>>>>>>>>....<.<<<
<<<<<..........>>>>>>>>>.>>>>>>>..>>.>>>>>>.<<<...
.<<....<<<<<<<.......>>>>>>>..>>......>>>..<<<<<<<
<....>>>>...>>>>.>>.<<<<<............>>>>>.<<<<...
.>>>>...>>>>>>.........<<<....<<<<....>>>>..>>>..>
>..>>>....<<<<<<...>>>>>>...<<<<<<<.........>>>>>>
>.....<<<<<((......<<<<.....<<..))>>.......>>>>.>>
>>>...>>>>>>>>..........<<<((.....<<<<...<<<.<<<<<
<<.<<<<<<<<<......<<<<<<<.....>>>>>>>....>>>>>>>..
>>>>>>>>>...<<<<<<.....<<<<<<<<<..<<<<<<<....<<<..
....>>>.......>>>>>>>..>>.......<<....>>.>>>>>>>..
..>>>.>>>...>>>...>>>>...<<<<<<<...<<...<<<<......
...>>>>...>>>>>>>>>.........<<<<<<..<<<<<<<<<<<<<<
.....>>>>>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<.
.....<<<<....>>>>....>>>..))))..<<<<<.<<<<<<<..<<.
<<<<<..<<<<<<<<<........<<........>>..........<<<<
<.<...<<<<<.......<<<.<<<.......>>>.>>>....>.>>>>.
..<<.<<<..<<<<<<<<.....<<<<<<.<<....>>...<<<<.....
.>>>>..>>>>>>....<<<<<.<<<<<<<...<..<<.<<<<<....>>
>>>.>>>....>>>>>>>.....<<<<<....>>>>>........>>>>>
.....>>.>>>...>>>>>>>>.....>>>>>>......>>>>>>>>.>.
..<<<<<<<.....<<...<<..<<<.....>>>..>>....>>.....>
>>>>>>...........<<<<<<<........>>>>>>>...........
>>>>>....<<<<<<<.........>>>>>>>......>>...>>>>>>>
>>>.>>....<..<<.<.<<<<.<<<..<<<.<<<<<<<<<..<<<<<<<
<<<.....>>>>>>>>>>..>>>>>>>>>.>>>..>>>.>>>>..>.>>.
..>.....<<<<<<<<<....>>>>>>>>>............
Receptor-Ligand Complex Structure
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PDB8hl5 Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
Resolution5.72 Å
Binding residue
(original residue number in PDB)
I4 N5 N9 T13 N16 R20 L26 T28 S31 K32 L33 R57 P80 L81 D82 Y83 Y92 R94 S108 T109 P110 G112 G125
Binding residue
(residue number reindexed from 1)
I1 N2 N6 T10 N13 R17 L23 T25 S28 K29 L30 R54 P77 L78 D79 Y80 Y89 R91 S105 T106 P107 G109 G122
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8hl5, PDBe:8hl5, PDBj:8hl5
PDBsum8hl5
PubMed37604686
UniProtO05636|RS8_SULAC Small ribosomal subunit protein uS8 (Gene Name=rps8)

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