Structure of PDB 8hkz Chain AS6E Binding Site BS01

Receptor Information
>8hkz Chain AS6E (length=105) Species: 330779 (Sulfolobus acidocaldarius DSM 639) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALAYRTRAFQLSLDQSKLPNLVGTKIGDVIDINVSGVNLKLKITGGSDNS
GFSMRFDVGGGAKRKILVSGPPGYYPKEDGLRRKRTVRGNMITPEIVQIN
TIMIR
Ligand information
>8hkz Chain A16S (length=1493) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auuccgguugauccugccggacccgaccgcuaucgggguagggauaagcc
augggagucuuacacucccggguaagggaguguggcggacggcugaguaa
cacguggcuaaccuacccucgggacggggauaaccccgggaaacugggga
uaauccccgauagggaaggaguccuggaaugguuccuucccuaaagggcu
auaggcuauuucccguuuguagccgcccgaggauggggcuacggcccauc
aggcugucggugggguaaaggcccaccgaaccuauaacggguaggggccg
uggaagcgggagccuccaguugggcacugagacaagggcccaggcccuac
ggggcgcaccaggcgcgaaacguccccaaugcgcgaaagcgugagggcgc
uaccccgagugccuccgcaggaggcuuuuccccgcucuaaaaaggcgggg
gaauaagcggggggcaagucuggugucagccgccgcgguaauaccagcuc
cgcgaguggucggggugauuacugggccuaaagcgccuguagccggccca
ccaagucgccccuuaaaguccccggcucaaccggggaacugggggcgaua
cuggugggcuagggggcgggagaggcgggggguacucccggaguaggggc
gaaauccuuagauaccgggaggaccaccaguggcggaagcgccccgcuag
aacgcgcccgacggugagaggcgaaagccggggcagcaaacgggauuaga
uaccccgguagucccggcuguaaacgaugcgggcuaggugucgaguaggc
uuagagccuacucggugccgcagggaagccguuaagcccgccgccugggg
aguacggucgcaagacugaaacuuaaaggaauuggcgggggagcaccaca
agggguggaaccugcggcucaauuggagucaacgccuggaaucuuaccgg
gggagaccgcaguaugacggccaggcuaacgaccuugccugacucgcgga
gaggaggugcauggccgucgccagcucguguugugaaauguccgguuaag
uccggcaacgagcgagacccccaccccuaguugguauucuggacuccggu
ccagaaccacacuagggggacugccggcguaagccggaggaaggaggggg
ccacggcaggucagcaugccccgaaacucccgggccgcacgcggguuaca
auggcagggacaacgggaugcuaccucgaaagggggagccaauccuuaaa
cccugccgcaguugggaucgagggcugaaacccgcccucgugaacgagga
aucccuaguaaccgcgggucaacaacccgcggugaauacgucccugcucc
uugcacacaccgcccgucgcuccacccgagcgagaaaggggugagguccc
uugcgauaagugggggaucgaacuccuuucccgcgaggggggagaagucg
uaacaagguagccguaggggaaccugcggcuggaucaccucau
...<<<<<.[.((((>>>>>.<<<<<<<<<.....<<<.<<......<<<
.<<<..<<<..<<<<<<<<......>>>>>>>>>>>......<<......
..<<<<<<...<<...<<<<<<<.<<<<<....<<<<<......>>>>>.
....>>>>>...<<<<<<<<..<<......>>.>>>>>>>>.....<<<<
<<<..............>>>>>>>.>>>>>>>..>>.>>>>>>.<<<...
.<<...<<<<<<<<.......>>>>>>>>.>>......>>>..<<<<<<<
<....>>>>...>>>>.>>.<<<<<............>>>>>.<<<<...
.>>>>...>>>>>>.........<<<....<<<<....>>>>..>>>..>
>..>>>....<<<<<<...>>>>>>...<<<<<<<.........>>>>>>
>.....<<<<<((......<<<<.....<<..))>>.......>>>>.>>
>>>..>>>>>>>>>..........<<<((.....<<<<...<<<.<<<<<
<<.<<<<<<<<<......<<<<<<<.....>>>>>>>....>>>>>>>..
>>>>>>>>>...<<<<<<.....<<<<<<<<<<.<<<<<<<....<<<..
....>>>.......>>>>>>>.>>>.......<<....>>.>>>>>>>..
..>>>.>>>...>>>...>>>>...<<<<<<<...<<...<<<<......
...>>>>...>>>>>>>>>.........<<<<<<..<<<<<<<<<<<<<<
.....>>>>>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<.
.....<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<..<<.
<<<<<<.<<<<<<<<<<<......<<........>>..........<<<<
<.....<<<<<.......<<<.<<<.......>>>.>>>....>.>>>>.
..<<.<<<..<<<<<<<<.....<<<<<<<<<....>>>..<<<<.....
.>>>>..>>>>>>....<<<<<.<<<<<<<..........<<<<....>>
>>.........>>>>>>.>....<<<<<....>>>>>........>>>>>
.....>>.>>>...>>>>>>>>......>>>>>...>>.>>>>>>>>.>.
..<<.<<<<.....<<...<<..<<<<....>>>>..>>....>>.....
>>>>.>>...........<<<<<<<........>>>>>>>..........
>>>>>>....<<<<<<<<.......>>>>>>>>......>>...>>>>>>
>>>>.>>....<..<<.<.<<<<.<<<..<<<.<<<<<<<<<..<<<<<<
<<<<.....>>>>>>>>>>..>>>>>>>>>.>>>..>>>.>>>>..>.>>
...>.....<<<<<<<<<....>>>>>>>>>............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8hkz Cryo-electron microscopy structure and translocation mechanism of the crenarchaeal ribosome.
Resolution4.78 Å
Binding residue
(original residue number in PDB)		R113 T114 A116 Q118 S120 K133 T152 S155 D156 N157 S158 G159 F160 R163 D165 V166 R172 I174 L175 V176 S177 P180 G181 Y183 D187 G188 R191 K192 T194 V205 N208 I210
Binding residue
(residue number reindexed from 1)		R5 T6 A8 Q10 S12 K25 T44 S47 D48 N49 S50 G51 F52 R55 D57 V58 R64 I66 L67 V68 S69 P72 G73 Y75 D79 G80 R83 K84 T86 V97 N100 I102
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8hkz, PDBe:8hkz, PDBj:8hkz
PDBsum8hkz
PubMed37604686
UniProtQ4JAI1|RS6E_SULAC Small ribosomal subunit protein eS6 (Gene Name=rps6e)

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