Structure of PDB 8hl4 Chain AS2P Binding Site BS01

Receptor Information
>8hl4 Chain AS2P (length=196) Species: 330779 (Sulfolobus acidocaldarius DSM 639) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELLVPLDTYLSAGVHIGTHTCTRYMERFIYRVRPEGLYVLDVRKIDERLR
VAAKFISRFRPEAVLTVASRPYAFTPVQKFSEVVRGKEISGRFPPGTLTN
PYLDNYIEPEVLIVTDPRTDLQAIKEASKVGIPIVAFTDTDARVDFIDVI
IPANNKGRKSLALLYWVLARQILRERKEIPLDGDIPLRVEDFETRL
Ligand information
>8hl4 Chain A16S (length=1492) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auuccgguugauccugccggacccgaccgcuaucgggguagggauaagcc
augggagucuuacacucccggguaagggaguguggcggacggcugaguaa
cacguggcuaaccuacccucgggacggggauaaccccgggaaacugggga
uaauccccgauagggaaggaguccuggaaugguuccuucccuaaagggcu
auaggcuauuucccguuuguagccgcccgaggauggggcuacggcccauc
aggcugucggugggguaaaggcccaccgaaccuauaacggguaggggccg
uggaagcgggagccuccaguugggcacugagacaagggcccaggcccuac
ggggcgcaccaggcgcgaaacguccccaaugcgcgaaagcgugagggcgc
uaccccgagugccuccgcaggaggcuuuuccccgcucuaaaaaggcgggg
gaauaagcggggggcaagucuggugucagccgccgcgguaauaccagcuc
cgcgaguggucggggugauuacugggccuaaagcgccuguagccggccca
ccaagucgccccuuaaaguccccggcucaaccggggaacugggggcgaua
cuggugggcuagggggcgggagaggcgggggguacucccggaguaggggc
gaaauccuuagauaccgggaggaccaccaguggcggaagcgccccgcuag
aacgcgcccgacggugagaggcgaaagccggggcagcaaacgggauuaga
uaccccgguagucccggcuguaaacgaugcgggcuaggugucgaguaggc
uuagagccuacucggugccgcagggaagccguuaagcccgccgccugggg
aguacggucgcaagacugaaacuuaaaggaauuggcgggggagcaccaca
agggguggaaccugcggcucaauuggagucaacgccuggaaucuuaccgg
gggagaccgcaguaugacggccaggcuaacgaccuugccugacucgcgga
gaggaggugcauggccgucgccagcucguguugugaaauguccgguuaag
uccggcaacgagcgagacccccaccccuaguugguauucuggacuccggu
ccagaaccacacuagggggacugccggcguaagccggaggaaggaggggg
ccacggcaggucagcaugccccgaaacucccgggccgcacgcggguuaca
auggcagggacaacgggaugcuaccucaaagggggagccaauccuuaaac
ccugccgcaguugggaucgagggcugaaacccgcccucgugaacgaggaa
ucccuaguaaccgcgggucaacaacccgcggugaauacgucccugcuccu
ugcacacaccgcccgucgcuccacccgagcgagaaaggggugaggucccu
ugcgauaagugggggaucgaacuccuuucccgcgaggggggagaagucgu
aacaagguagccguaggggaaccugcggcuggaucaccucau
...<<<<<.[.((((>>>>>.<<<<<<<<<.....<<<.<<......<<<
.<<<..<<<..<<<<<<<<......>>>>>>>>>>>......<<......
..<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<......>>>>>.
....>>>>>..<<<<<<<<<<.<<......>>>>>>>>>>>>...<.<<<
<<<..............>>>>>>>.>>>>>>>..>>>>>>>>>.<<<...
.<<...<<<<<<<<.......>>>>>>>>.>>......>>>..<<<<<<<
<....>>>>...>>>>.>>.<<<<<............>>>>>.<<<<...
.>>>>...>>>>>>.........<<<....<<<<....>>>>..>>>..>
>..>>>....<<<<<<...>>>>>>...<<<<<<<.........>>>>>>
>.....<<<<<((......<<<<.....<<..))>>.......>>>>.>>
>>>..>>>>>>>>>..........<<<((.....<<<<...<<<.<<<<<
<<.<<<<<<<<<......<<<<<<<.....>>>>>>>....>>>>>>>..
>>>>>>>>>...<<<<<<.....<<<<<<<<<<.<<<<<<<....<<<..
....>>>.......>>>>>>>.>>>.......<<....>>.>>>>>>>..
..>>>.>>>...>>>...>>>>...<<<<<<<...<<...<<<<.<....
.>.>>>>...>>>>>>>>>.........<<<<<<..<<<<<<<<<<<<<<
.....>>>>>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<.
.....<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<..<<.
<<<<<<..<<<<<<<<<<......<<........>>..........<<<<
<.<...<<<<........<<<.<<<.......>>>.>>>......>>>>.
..<<.<<<..<<<<<<<<.....<<<<<<<<<....>>>..<<<<.....
.>>>>..>>>>>>....<<<<<.<<<<<<<.<<<..<<<<<<<<....>>
>>>>>>>>..>>>>>>>>.....<<<<<....>>>>>........>>>>>
.....>>.>>>...>>>>>>>>.....>>>>>>...>>.>>>>>>>>...
..<<<<<<<.....<<...<<..<<<.....>>>..>>....>>.....>
>>>>>>......<....<<<<<<<........>>>>>>>....>.....>
>>>>>....<<<<<<<<.......>>>>>>>>......>>...>>>>>>>
>>>.>>....<..<<.<.<<<<.<<<..<<<.<<<<<<<<<..<<<<<<<
<<<.....>>>>>>>>>>..>>>>>>>>>.>>>..>>>.>>>>..>.>>.
..>.....<<<<<<<<<....>>>>>>>>>............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8hl4 Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
Resolution4.62 Å
Binding residue
(original residue number in PDB)		R50 Y51 P61 R119 P122 T126 N127 Y129 Q149 K152 R170
Binding residue
(residue number reindexed from 1)		R23 Y24 P34 R92 P95 T99 N100 Y102 Q122 K125 R143
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8hl4, PDBe:8hl4, PDBj:8hl4
PDBsum8hl4
PubMed37604686
UniProtP39478|RS2_SULAC Small ribosomal subunit protein uS2 (Gene Name=rps2)

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