Structure of PDB 9bdp Chain AS19 Binding Site BS01

Receptor Information
>9bdp Chain AS19 (length=141) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENW
FYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVARR
VLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAKK
Ligand information
>9bdp Chain A18S (length=1691) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucgacuuggauaacugugguaau
ucuagagcuaauacaugccgacgggcgcugacccccuucgcgggggggau
gcgugcauuuaucaguggugacucuagauaaccucgggccgaucgcacgc
ggcggcgacgacccauucgaacgucugcccuaucaacuuucgaugguagu
cgccgugccuaccauggugaccacgggugacggggaaucaggguucgauu
ccggagagggagccugagaaacggcuaccacauccaaggaaggcagcagg
cgcgcaaauuacccacucccgacccggggagguagugacgaaaaauaaca
auacaggacucuuucgaggcccuguaauuggaaugaguccacuuuaaauc
cuuuaacgaggauccauuggagggcaagucuggugccagcagccgcggua
auuccagcuccaauagcguauauuaaaguugcugcaguuaaaaagcucgu
aguuggaucuugggagcggccguccccugcucggcgccggcccgaagcgu
uuacuuugaaaaaauuagaguguucaaagcaggccgccuggauaccgcag
cuaggaauaauggaauaggaccgcgguucuauuuuguugguuuucggaac
ugaggccaugauuaagagggacggccgggggcauucguauugcgccgcua
gaggugaaauucuuggaccggcgcaagacggaccagagcgaaagcauuug
ccaagaauguuuucauuaaucaagaacgaaagucggagguucgaagacga
ucagauaccgucguaguuccgaccauaaacgaugccgacuggcgaugcgg
cggcguuauucccaugacccgccgggcagcuuccgggaaaccaaagucuu
uggguuccggggggaguaugguugcaaagcugaaacuuaaaggaauugac
ggaagggcaccaccaggaguggagccugcggcuuaauuugacucaacacg
ggaaaccucacccggcccggacacggacaggauugacagauugauagcuc
uuucucgauuccgugggugguggugcauggccguucuuaguugguggagc
gauuugucugguuaauuccgauaacgaacgagacucuggcaugcuaacua
guuacgcgaccccggucggcguaacuucuuagagggacaaguggcguuca
gccacccgagauugagcaauaacaggucugugaugcccuuagauguccgg
ggcugcacgcgcgcuacacugacuggcucagcgugugccuacccuacgcc
ggcaggcgcggguaacccguugaaccccauucgugauggggaucggggau
ugcaauuauuccccaugaacgaggaauucccaguaagugcgggucauaag
cuugcguugauuaagucccugcccuuuguacacaccgcccgucgcuacua
ccgauuggaugguuuagugaggcccucggaucggccccgccgggccuggc
ggagcgcugagaagacggucgaacuugacuaucuagaggaaguaaaaguc
guaacaagguuuccguaggugaaccugcggaaggaucauua
...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<.....<<..........>>....>.>>......<<...
.....<<<.<....<<....<<<..........<<.....<<.<<<....
.>>>.>>......>>.........<<<<...<<<<<<....>>>>>>...
>>>><<..<<<<<...<......>..>>>>>......>>...<<<<..<<
.>>.>>>>....>>>...>>..>.>>>.<<<....<<<....<<<<<<<.
........>>>>>>>>>>......>>>...<<<.<<<<....>>>>....
>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>>>
>.........<<<....<<<<...>>>>..>>>..>...>>.>.....<<
<<<<<<<.<<<....>>>..>>>>>>.>>>......<<..<.........
..>..>>.........<<<<<((......<<<<.....<<..))>>....
...>>>>.>>>>>..>>>>>>.>>>.........<.<((.....<.<<..
.<<<.<<.....<<.<<<..>>>.>>.<<<<<<<.<<..>>>>>>.>>>.
<<<<<<.<.......<<...<.......>.<<<<.>>>>...>>......
>.>>>..>>>........<.<<.<<<<<<<...............>>>>>
>>.>>.>....>>....<<<<<<..<...<<<<..<<..<<<<<<<<...
<<<......>>>......>>>>>>>>..>>.......<<....>>...>>
>>..>..>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<.
<.....>.>>>>...>>>>>>>>..........<<<.<<.<<<..<.<<<
<<<.<<<<......>>>>>>>>>>.>..>>>...<<..))>>...>>...
..>>>.>.>.<<<......<<<<....>>>>....>>>..)))).]<<<<
<.<<<<<<<..<<..<<<<<..<<<.<<<<<<......<<........>>
..........<<<<<......<<<<<<.......<<.<<<........>>
>.>>.....>>>>>>...<<.<<<..<<.<<<<<<....<<<.<<<<...
...>>...<<<......>>>...>>.>>>....<<<...<...<<<...<
<<<<<<<<<<<..>>>>.>>>>>>>>...>>>..>.....<<<<<.....
>>>>>........>>>....>>>.>>>.....>>>>>>>.......>>>>
>...>>.>>>>.>>>.....<<.<<<........<.......<<<.<<<<
....>>>>.>>>....>.........>>>.>>............<<<<<.
.........>>>>>...........>>>>>.....<<<<<<<<.......
>>>>>>>>......>>...>>>>>>>>>>.>>.......<<.<..<<<<.
<<....<<<<<<<<.<<<..<<<<.<<...<<<<<.<<<<<<<..>>>>>
>>...>>>>>...>>.>>>>..>>>.>>>>>>>>...>>.>>>>...>.>
>.........<<<<<<<<<....>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9bdp Structural mechanism of angiogenin activation by the ribosome.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		G3 K7 Q11 Q12 V15 W33 L39 K41 K43 E44 P47 Y48 R62 H63 R67 G71 V72 G73 S74 K77 I78 Y79 R82 R84 G86 V87 M88 P89 S90 H91 F92 S96 K97 S98 R101 R102 Q105 R121 P125 Q128 R129 D132 R133
Binding residue
(residue number reindexed from 1)		G1 K5 Q9 Q10 V13 W31 L37 K39 K41 E42 P45 Y46 R60 H61 R65 G69 V70 G71 S72 K75 I76 Y77 R80 R82 G84 V85 M86 P87 S88 H89 F90 S94 K95 S96 R99 R100 Q103 R119 P123 Q126 R127 D130 R131
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000028 ribosomal small subunit assembly
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:9bdp, PDBe:9bdp, PDBj:9bdp
PDBsum9bdp
PubMed38718836
UniProtG1TN62|RS19_RABIT Small ribosomal subunit protein eS19 (Gene Name=RPS19)

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