Structure of PDB 9bdn Chain AS11 Binding Site BS01

Receptor Information
>9bdn Chain AS11 (length=143) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DIQTERAYQKQPTIFQNKKRVKLPRYYKNIGLGFKTPKEAIEGTYIDKKC
PFTGNVSIRGRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMS
VHLSPCFRDVQIGDIVTVGECRPLSKTVRFNVLKVTKAAGTKK
Ligand information
>9bdn Chain A18S (length=1691) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucgacuuggauaacugugguaau
ucuagagcuaauacaugccgacgggcgcugacccccuucgcgggggggau
gcgugcauuuaucaguggugacucuagauaaccucgggccgaucgcacgc
ggcggcgacgacccauucgaacgucugcccuaucaacuuucgaugguagu
cgccgugccuaccauggugaccacgggugacggggaaucaggguucgauu
ccggagagggagccugagaaacggcuaccacauccaaggaaggcagcagg
cgcgcaaauuacccacucccgacccggggagguagugacgaaaaauaaca
auacaggacucuuucgaggcccuguaauuggaaugaguccacuuuaaauc
cuuuaacgaggauccauuggagggcaagucuggugccagcagccgcggua
auuccagcuccaauagcguauauuaaaguugcugcaguuaaaaagcucgu
aguuggaucuugggagcggccguccccugcucggcgccggcccgaagcgu
uuacuuugaaaaaauuagaguguucaaagcaggccgccuggauaccgcag
cuaggaauaauggaauaggaccgcgguucuauuuuguugguuuucggaac
ugaggccaugauuaagagggacggccgggggcauucguauugcgccgcua
gaggugaaauucuuggaccggcgcaagacggaccagagcgaaagcauuug
ccaagaauguuuucauuaaucaagaacgaaagucggagguucgaagacga
ucagauaccgucguaguuccgaccauaaacgaugccgacuggcgaugcgg
cggcguuauucccaugacccgccgggcagcuuccgggaaaccaaagucuu
uggguuccggggggaguaugguugcaaagcugaaacuuaaaggaauugac
ggaagggcaccaccaggaguggagccugcggcuuaauuugacucaacacg
ggaaaccucacccggcccggacacggacaggauugacagauugauagcuc
uuucucgauuccgugggugguggugcauggccguucuuaguugguggagc
gauuugucugguuaauuccgauaacgaacgagacucuggcaugcuaacua
guuacgcgaccccggucggcguaacuucuuagagggacaaguggcguuca
gccacccgagauugagcaauaacaggucugugaugcccuuagauguccgg
ggcugcacgcgcgcuacacugacuggcucagcgugugccuacccuacgcc
ggcaggcgcggguaacccguugaaccccauucgugauggggaucggggau
ugcaauuauuccccaugaacgaggaauucccaguaagugcgggucauaag
cuugcguugauuaagucccugcccuuuguacacaccgcccgucgcuacua
ccgauuggaugguuuagugaggcccucggaucggccccgccgggccuggc
ggagcgcugagaagacggucgaacuugacuaucuagaggaaguaaaaguc
guaacaagguuuccguaggugaaccugcggaaggaucauua
...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<.<....<<....<<<<<........<<.....<<.<<<....
.>>>.>>......>>.........<<<<...<<<<<<....>>>>>>...
>>>><<..<<<<<...<......>..>>>>>......>>...<<<<.<<<
.>>>>>>>.>>.>>>...>>..>.>>>.<<<....<<<....<<<<<<<.
........>>>>>>>>>>......>>>...<<<.<<<<....>>>>....
>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>>>
>.........<<<....<<<<...>>>>..>>>..>...>>.>.....<<
<<<<<<<.<<<....>>>..>>>>>>.>>>......<<..<.........
..>..>>.........<<<<<((....<.<<<<.....<<..))>>....
...>>>>>>>>>>..>>>>>>.>>>.........<.<((.....<.<<..
.<<<.<<....<<<.<<<..>>>.>>><<<<<<<.<<..>>>>>>.>>>.
<<<<<<.<.......<<...<.......>.<<<<.>>>>...>>......
>.>>>..>>>........<.<<.<<<<<<<...............>>>>>
>>.>>.>....>>....<<<<<<..<...<<<<..<<..<<<<<<<<...
<<<......>>>......>>>>>>>>..>>.......<<....>>...>>
>>..>..>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<.
<.....>.>>>>...>>>>>>>>..........<<<.<<.<<<..<.<<<
<<<.<<<<<....>>>>>>>>>>>.>..>>>...<<..))>>...>>...
..>>>.>.>.<<<......<<<<....>>>>....>>>..)))).]<<<<
<.<<<<<<<..<<..<<<<<..<<<.<<<<........<<........>>
..........<<<<<......<<<<<<.......<<.<<<........>>
>.>>.....>>>>>>.<.<<.<<<..<<.<<<<<<....<<<.<<<<<..
..>>>...<<<......>>>...>>.>>>....<<<...<...<<<<..<
<<<<<<<<<<<..>>>>.>>>>>>>>..>>>>..>.....<<<<<.....
>>>>>........>>>....>>>.>>>.....>>>>>>>>......>>>>
>......>>>>.>>>.....<<.<<<........<.......<<<.<<<<
....>>>>.>>>....>.........>>>.>>......<.....<<<<<.
.........>>>>>.....>.....>>>>>.....<<<<<<<<.......
>>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<..<<<<.
<<....<<<<<<<<.<<<..<<<<.<<...<<<<<<<<<<<<<..>>>>>
>>.>.>>>>>...>>.>>>>..>>>.>>>>>>>>...>>.>>>>...>.>
>...>.....<<<<<<<<<<..>>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9bdn Structural mechanism of angiogenin activation by the ribosome.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		T15 F17 Y36 N39 I40 L42 K58 K59 N65 S67 R69 R71 K79 K81 M82 Q83 T85 Y92 H94 R97 K98 K104 R105 H106 K107 N108 E130 R132 P133 L134 S135 K136 T137 R139 F140 K152
Binding residue
(residue number reindexed from 1)		T13 F15 Y26 N29 I30 L32 K48 K49 N55 S57 R59 R61 K69 K71 M72 Q73 T75 Y82 H84 R87 K88 K94 R95 H96 K97 N98 E120 R122 P123 L124 S125 K126 T127 R129 F130 K142
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:9bdn, PDBe:9bdn, PDBj:9bdn
PDBsum9bdn
PubMed38718836
UniProtG1TRM4|RS11_RABIT Small ribosomal subunit protein uS17 (Gene Name=RPS11)

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