Structure of PDB 9bdn Chain AS09 Binding Site BS01

Receptor Information
>9bdn Chain AS09 (length=185) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLA
KIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLK
IEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRL
DSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAG
Ligand information
>9bdn Chain A18S (length=1691) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucgacuuggauaacugugguaau
ucuagagcuaauacaugccgacgggcgcugacccccuucgcgggggggau
gcgugcauuuaucaguggugacucuagauaaccucgggccgaucgcacgc
ggcggcgacgacccauucgaacgucugcccuaucaacuuucgaugguagu
cgccgugccuaccauggugaccacgggugacggggaaucaggguucgauu
ccggagagggagccugagaaacggcuaccacauccaaggaaggcagcagg
cgcgcaaauuacccacucccgacccggggagguagugacgaaaaauaaca
auacaggacucuuucgaggcccuguaauuggaaugaguccacuuuaaauc
cuuuaacgaggauccauuggagggcaagucuggugccagcagccgcggua
auuccagcuccaauagcguauauuaaaguugcugcaguuaaaaagcucgu
aguuggaucuugggagcggccguccccugcucggcgccggcccgaagcgu
uuacuuugaaaaaauuagaguguucaaagcaggccgccuggauaccgcag
cuaggaauaauggaauaggaccgcgguucuauuuuguugguuuucggaac
ugaggccaugauuaagagggacggccgggggcauucguauugcgccgcua
gaggugaaauucuuggaccggcgcaagacggaccagagcgaaagcauuug
ccaagaauguuuucauuaaucaagaacgaaagucggagguucgaagacga
ucagauaccgucguaguuccgaccauaaacgaugccgacuggcgaugcgg
cggcguuauucccaugacccgccgggcagcuuccgggaaaccaaagucuu
uggguuccggggggaguaugguugcaaagcugaaacuuaaaggaauugac
ggaagggcaccaccaggaguggagccugcggcuuaauuugacucaacacg
ggaaaccucacccggcccggacacggacaggauugacagauugauagcuc
uuucucgauuccgugggugguggugcauggccguucuuaguugguggagc
gauuugucugguuaauuccgauaacgaacgagacucuggcaugcuaacua
guuacgcgaccccggucggcguaacuucuuagagggacaaguggcguuca
gccacccgagauugagcaauaacaggucugugaugcccuuagauguccgg
ggcugcacgcgcgcuacacugacuggcucagcgugugccuacccuacgcc
ggcaggcgcggguaacccguugaaccccauucgugauggggaucggggau
ugcaauuauuccccaugaacgaggaauucccaguaagugcgggucauaag
cuugcguugauuaagucccugcccuuuguacacaccgcccgucgcuacua
ccgauuggaugguuuagugaggcccucggaucggccccgccgggccuggc
ggagcgcugagaagacggucgaacuugacuaucuagaggaaguaaaaguc
guaacaagguuuccguaggugaaccugcggaaggaucauua
...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<.<....<<....<<<<<........<<.....<<.<<<....
.>>>.>>......>>.........<<<<...<<<<<<....>>>>>>...
>>>><<..<<<<<...<......>..>>>>>......>>...<<<<.<<<
.>>>>>>>.>>.>>>...>>..>.>>>.<<<....<<<....<<<<<<<.
........>>>>>>>>>>......>>>...<<<.<<<<....>>>>....
>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>>>
>.........<<<....<<<<...>>>>..>>>..>...>>.>.....<<
<<<<<<<.<<<....>>>..>>>>>>.>>>......<<..<.........
..>..>>.........<<<<<((....<.<<<<.....<<..))>>....
...>>>>>>>>>>..>>>>>>.>>>.........<.<((.....<.<<..
.<<<.<<....<<<.<<<..>>>.>>><<<<<<<.<<..>>>>>>.>>>.
<<<<<<.<.......<<...<.......>.<<<<.>>>>...>>......
>.>>>..>>>........<.<<.<<<<<<<...............>>>>>
>>.>>.>....>>....<<<<<<..<...<<<<..<<..<<<<<<<<...
<<<......>>>......>>>>>>>>..>>.......<<....>>...>>
>>..>..>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<.
<.....>.>>>>...>>>>>>>>..........<<<.<<.<<<..<.<<<
<<<.<<<<<....>>>>>>>>>>>.>..>>>...<<..))>>...>>...
..>>>.>.>.<<<......<<<<....>>>>....>>>..)))).]<<<<
<.<<<<<<<..<<..<<<<<..<<<.<<<<........<<........>>
..........<<<<<......<<<<<<.......<<.<<<........>>
>.>>.....>>>>>>.<.<<.<<<..<<.<<<<<<....<<<.<<<<<..
..>>>...<<<......>>>...>>.>>>....<<<...<...<<<<..<
<<<<<<<<<<<..>>>>.>>>>>>>>..>>>>..>.....<<<<<.....
>>>>>........>>>....>>>.>>>.....>>>>>>>>......>>>>
>......>>>>.>>>.....<<.<<<........<.......<<<.<<<<
....>>>>.>>>....>.........>>>.>>......<.....<<<<<.
.........>>>>>.....>.....>>>>>.....<<<<<<<<.......
>>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<..<<<<.
<<....<<<<<<<<.<<<..<<<<.<<...<<<<<<<<<<<<<..>>>>>
>>.>.>>>>>...>>.>>>>..>>>.>>>>>>>>...>>.>>>>...>.>
>...>.....<<<<<<<<<<..>>>>>>>>>>.........
Receptor-Ligand Complex Structure
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PDB9bdn Structural mechanism of angiogenin activation by the ribosome.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
P2 V3 A4 R5 W7 V8 C9 R10 K11 T12 Y13 T15 R17 R18 P19 F20 R38 N39 K40 R41 R45 F72 E73 R80 K121 S122 H125 R127 V128 R131 Q132 H134 Q140 N143 I144 S146 F147 I148 R150 S153 R162 P164 Y165 R169 G171 R172 V173 K174 N177
Binding residue
(residue number reindexed from 1)
P1 V2 A3 R4 W6 V7 C8 R9 K10 T11 Y12 T14 R16 R17 P18 F19 R37 N38 K39 R40 R44 F71 E72 R79 K120 S121 H124 R126 V127 R130 Q131 H133 Q139 N142 I143 S145 F146 I147 R149 S152 R161 P163 Y164 R168 G170 R171 V172 K173 N176
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0043226 organelle
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:9bdn, PDBe:9bdn, PDBj:9bdn
PDBsum9bdn
PubMed38718836
UniProtB7NZS8|RS9_RABIT Small ribosomal subunit protein uS4 (Gene Name=RPS9)

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