Structure of PDB 6olz Chain AS Binding Site BS01

Receptor Information
>6olz Chain AS (length=175) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKASGTLREYKVVGRCLPTPKCHTPPLYRMRIFAPNHVVAKSRFWYFVSQ
LKKMKKSSGEIVYCGQVFEKSPLRVKNFGIWLRYDSRSGTHNMYREYRDL
TTAGAVTQCYRDMGARHRARAHSIQIMKVEEIAASKCRRPAVKQFHDSKI
KFPLPHRVLRRQHKPRFTTKRPNTF
Ligand information
>6olz Chain A4 (length=119) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucuacggccauaccacccugaacgcgcccgaucucgucugaucucggaa
gcuaagcagggucgggccugguuaguacuuggaugggagaccgccuggga
auaccgggugcuguaggcu
<<<<<<<<<....<<<<<<<<.....<<<<<..............>>>..
>>....>>>>>>.>><<<<<<<......<.<<..<<....>>.>>.>...
..>>>>>>>>>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB6olz Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		K21 S42 Y46 S49 Q50 K53 M54 K55 S57 R87 H122
Binding residue
(residue number reindexed from 1)		K21 S42 Y46 S49 Q50 K53 M54 K55 S57 R87 H122
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6olz, PDBe:6olz, PDBj:6olz
PDBsum6olz
PubMed31160784
UniProtQ02543|RL18A_HUMAN Large ribosomal subunit protein eL20 (Gene Name=RPL18A)

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