Structure of PDB 6eri Chain AS Binding Site BS01

Receptor Information

>6eri Chain AS (length=171) Species: 3562 (Spinacia oleracea)

EPGKCDEITTRGYSISMSVDKARRVIDQIRGRSYAETLMILELMPYRACY
PIFKLIYSAAANASHNKQFNKANLIISKAEVNKGITLKKVKPRARGRSYM
IKRPTCHITIVLRDITHFDSYDKFLESLTPKKLIALLGLMSTGRRRELLC
GRFRENHKIKSFLYKIALFKR

Ligand information

>6eri Chain AA (length=2696)

ucaaacgaggaaaggcuuacgguggauaccuaggcacccagagacgagga
agggcguauuaaucgacgaaaugcuucggggaguugaaaauaagcagaga
uccggagauucccgaauaggucaaccuuucgaacuucugcugaauccaug
ggcaggcaagagacaaccuggcgaacugaaacaucuuaguagccagagga
aaagaaagcaaaagcgauucccguaguagcggcgagcgaaaugggagcag
ccuaaaccgugaaaacgggguugugggagagcaauacaagcgucgugcug
cuaggcgaaucaguggagugcggaacccuagauggugaaaguccaguagc
cgaaagcaucacuagcuuaugcucugacccgaguagcauggggcacgugg
aaucccgugugaaucagcaaggaccaccuugcaaggcuaaauacuccugg
gugaccgauagcgaaguaguaccgugagggaagggugaaaagaaccccca
ucggggagugaaauagaacaugaaaccguaagcucucaagcagugggagg
gggaccagacccugaccgcgugccuguugaagaaugagccggcgacucau
aggcaguggcuugguuaagggaacccaccggagccguagcgaaagcgagu
cuucauagggcaauugucacugcuuauggacccgaaccugggugaucuau
ccaugaccaggaugaagcuugggugaaacuaaguggagguccgaaccgac
ugauguugaagaaucagcggaugaguugugguuaggggugaaaugccacu
cgaacccagagcuagcugguucuccccgaaaugcguugaggcgcagcagu
ugacuggacaucuagggguaaagcacuguuucggugcgggccgcgguacc
aaaucgaggcaaacucugaauacuagauaugaccuccaaauaacaggggu
caaggucggccagugagacgaugggggauaagcuucaucgucgagaggga
aacagcccggaucaccagcuaaggccccuaaaugaccgcucagugauaaa
ggagguaggggugcagagacagccaggagguuugccuagaagcagccacc
cuugaaagagugcguaauagcucacugaucgagcgcucuugcgccgaaga
ugaacggggcuaagcggucugccgaagcugugggauguaaaaaaacaucg
guaggggagcguuccguguuagggagaaacgcgugcgugagccgcguugg
acgaagcggaagcgagaaugucggcuugaguaacgcaaacauuggugaga
auccaaugccccgaaaaccuaaggguuccuccgcaagguucguccacgga
gggugagucagggccuaagaucaggccgaaaggcguagucgauggacaac
aggugaauauuccuguacuaccccuuguuggucccgagggacggaggagg
cuagguuagccgaaagaugguuaucgguucaaggacgcaaggugacccgg
guaagaagggguagagaaaaugccucgagccaauguucgaguaccaggcg
cuacggcgcugaaguaaccgaugccauacucccaggaaaagcucgaacga
ccuucaacaaaaggguaccuguacccgaaaccgacacagguagguaggua
gagaauaccuaggggcgcgagacaacucucucuaaggaacucggcaaaau
agccccguaacuucgggagaaggggugcccccucacaaagggggucgaag
ugaccaggcccgggcgacuguuuaccaaaaacacaggucuccgcaaaguc
guaagaccauguaugggggcugacgccugcccagugccggaaggucaagg
aaguuggugaccugacaggggagccggcgaccgaagccccggugaacggc
ggccguaacuauaacgguccuaagguagcgaaauuccuugucggguaagu
uccgacccgcacgaaaggcguaacgaucugggcacugucucggagagagg
cucggugaaauagacaugucugugaagaugcggacuaccugcaccuggac
agaaagacccuaugaagcuuuacuguucccugggauuggcuuauucuaac
cuugugucaggaccuacgggccaagggacauucucagguagacaguuucu
auggggcguaggccucccaaaagguaacggaggcgugcaaagguuuccuc
gggccggacggagauuggcccucgagugcaaaggcagaagggagcuugac
ugcaagacccacccgucgagcagggacgaaagucggccuuagugauccga
cggugccgaguggaagggccgucgcucaacggauaaaaguuacucuaggg
auaacaggcugaucuuccccaagaguucacaucgacgggaagguuuggca
ccucgaugucggcucuucgccaccuggggcuguaguauguuccaaggguu
gggcuguucgcccauuaaagcgguacgugagcuggguucagaacgucgug
agacaguucgguccauauccggugugggcguuagagcauugagaggaccu
uucccuaguacgagaggaccgggaaggacgcaccucugguguaccaguua
ucgugcccacgguaaacgcuggguagccaagugcggagcggauaacugcu
gaaagcaucuaaguaguaagcccaccccaagaugagugcucuccua

.............<<<<<<<<<<.....<<..<<<<<<<<<<<.<.....
.<<<<<<.....((.>>>.....<<<<<<<..<<.))......>>.....
>>>>>>>...>>>....<<<....>>>......<<<<<<<<.........
>>>>>..>>>.>....<<<<<<.....<......>......>>>>>.>..
.......<<....>>..<<<<<<.....<<.....>>....>>>>>>..<
<<....<<<<....>>>>......<<<<<<<<......<<....<<<.<<
<<.<<<...<<.<<.....>>.>>((......<<<.....))>>>...>>
>...>>>>.>>>....>>..>>>>>..>>>.....<<<<<<<<.......
..>>>>>>>>......<<<<<..<<<<>>>>>..>>>......>>.>>>>
>>>.>>...............<<....>>....>>.........<<<<..
..>>>>..................>>>>>>>>>>........<<<<..<<
<<.......>>>>..>>>>...<.<........>.>.<<<<<<....<<<
<<<<<<<<<...<<<...<<.......>>...>>>...<<....>>..<<
<<.....>>>>.....>>>>>>>>>>>>..<<.<...<<<<<<.....<.
<<<<<<<..<<<....<<<<<<......>>>>>>.....>>>...<<<.<
<<<<........>>>>>>>>....>>>>>>>.>...<<<.....>>>...
...>>>>>>......>.>>..<<<<<<....<<<<<....>>>>><<.<<
<<<<<....<<<<<<......<<...<<<<<<<<...<...........>
...>>>>>>>>..>>.......>>>>>>..<<<<<...........>>>>
>..>>>>>>>..>>..<<<<<<<<<<......>>>>>>>>>>....<<<.
.....>>>...<<<<.<<<...<<<(((.....<<<<<<...........
<<..<<<<<<<<<<.......<.<<<.<<<...<<.........>>...>
>>.........<<......>>...>>>.>...>>>>>>>>>>.>>.....
.....))).....>>>>>>.>>>...>>>>>>><<<<<......>>>>>.
...>>>>>><<<<<<<<...........<<<<<.<<....>>>>>>.>..
.....>>>>>>.>>.....>>>>>><......<<.....<<<<<<.....
..>>>>>><<<<....<<<<<.<<...<<<<<<...<<.....>>.>>>>
>>....((<<<<.<<...<<<...<<<....>>>...>>>...>>...<<
<<<........>>>>>))<<<<<.<<<<.<<<<.<<<<....<<<<..<<
<..<<<<<<<<<<.....(((..>>>>>....<<<<<...<<<.<<....
>>.....<<<<<<.......>>>>>>..>>>..>>>>>.....<..<<<<
<....>>>>>...>>>>>>...>>>...>>>>.........>>>>...>>
>>....>>.>>.>>>>>>>>>..>>.....<<......>>>>>>>.<<<<
.....>>>>..>>>>..<<<<....<<<<<<<<.<<..............
.<<<<<...............>>>>><<<<<<.......>>>>>>.....
.......<<<<<<<<<..<<<.........>>>..<<<<<<<.....<<<
....>>>.......>>>>>>>.<<<<<.<<<..<<<<<<<..<<<...<<
..<<<<<<..<<<<.>>>>...>>>>>>..>>...>>>>>>>>..>>>>>
<<<<<<.......>>>>>>........<...........<<<<<<.....
>>>>>>.....>....>>>>>..>>.>>>>>>>.....>>.>>>>>>>>.
>>>>>>.....>.....<<<<<........>>>>>..<<<<<<<<.<<<.
.<......<<<<.<<<<<<..<<<<<..<<<<<<<..<<.<.>.>>...<
<<<<.<<<..........>>>>>>>>.....>>>>>>>...>>>>>..<<
<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<..
<<<<<<<.......>>>>>>>....<<...(((>>....>>>>>>>...<
<<<..<<<......>>>..>>>>.<<<....>>>.>>))).......<<<
<<<<.<<..>>>>..>>>>>>>>>.............>>>>..>>>>>>.
......<<<<.<.<<<<<<...<<.......>>...>>>>>>...>>>>.
>.......<<<<<.<.<<<<..<<<<<<<<........>>>>>..>>>.<
<<<<.....>>>>>.....>>>>...>...>>>.>>....<<<<<<<...
.>>>.>>>>....>...>>>>>>>>>>>....<<<<<<<...<.<<..<<
<<<<<...............>>>>>>>.<<<<<...<<<<...<<<<<<<
<<<<))).>>>>>>...>>>>>...>>>>.>>>>>..<.<<.<.<<<<<<
...........>>>>>>..>>>>.>>.>.......>>>>>>>....

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6eri Structure of the chloroplast ribosome with chl-RRF and hibernation-promoting factor.
• Resolution: 3.0 Å
• Binding residue (original residue number in PDB): R35 Y37 S38 S42 K45 R47 R48 R71 K78 Y81 S82 A85 N86 H89 N90 N106 K107 I109 K112 K113 K115 P116 R117 A118 G120 R121 Y123 I125 K126 R127 S185 R195
• Binding residue (residue number reindexed from 1): R11 Y13 S14 S18 K21 R23 R24 R47 K54 Y57 S58 A61 N62 H65 N66 N82 K83 I85 K88 K89 K91 P92 R93 A94 G96 R97 Y99 I101 K102 R103 S161 R171

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0015934 large ribosomal subunit

External links

• PDB: RCSB:6eri, PDBe:6eri, PDBj:6eri
• PDBsum: 6eri
• PubMed: 29610536
• UniProt: P09594|RK22_SPIOL Large ribosomal subunit protein uL22c (Gene Name=rpl22)