Structure of PDB 4v7h Chain AQ Binding Site BS01

Receptor Information

>4v7h Chain AQ (length=80) Species: 5541 (Thermomyces lanuginosus)

RGKILTGTVVSTKMHRTIVIRRAYLHYIPKYNRYEKRHKNVPVHVSPAFR
VQVGDIVTVGQCRPISKTVRFNVVKVSAAA

Ligand information

>4v7h Chain AA (length=1761)

uaucugguugauccugccaguagucauaugcuugucucaaaguuaagcca
ugcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcucau
uaaaucaguuauguuuauuugauagacauggauaaccgugguauucuaga
gcuaauacaugcuuaaaaucucgacccuuuggaagagauguauuuauuag
auaaaaaaucaaugucuucggacucuuugaugauucauaauaacuuuucg
aaucgcauggccuugugcuggcgaugguucauucaaauuucugcccuauc
aacuugaugguaggauaguggccuaccaugguuucaacggguacggggaa
uaaggguucgauuccggagagggagccugagaaacggcuaccacauccaa
ggaaggcagcaggcgcgcaaauuacccaauccuaauucagggagguagug
acaauaaauaacgauacagggcccauucgggucuuguaauuggaaugagu
acaauguaaauaccuuaacgaggaacaauuggaggcaagucuggugccag
cagccgcgguaauuccagcuccaauagcguauauuaaaguuguugcaguu
aaaaagcucguaguugacuuugggcccgguuggccgguccgauuuuuucg
uguacuggauuuccaacggggccuuuccuucuggcuaaccuugaguccuu
guggcucuuggcgaaccaggacuuuacuuugaaaaaauuagaguguucaa
agcaggcguauugcucgaauauauuagcauggaauaauagaauaggacuu
ugguucuauuuuguugguuucuaggaccaucguaaugauuagggacgguc
gggggcaucgguauucaauugucgaggugaaauucuuggauuuauugaag
acuaacuacugcgaaagcauuugccaaggacguuuucauuaaucaagaac
gaaaguuaggggaucgaagaugaucugguaccgucguagucuuaaccaua
aacuaugccgacuagaucgggugguguuuuuuuaaugaccacucgguacc
uuacgagaaaucaaagucgguucuggggggaguauggucgcaaggcugaa
acuuaaaggaauugacggaagggcacccuaggaguggagccugcggcuaa
uuugacucaacacggggaaacucaccagguccagacacaauaaggauuga
cagauugagagcucuuucuugauuuugugggugguggugcauggccguuu
cuaguugguggagugauuugucugcuuaauugcgauaacgaacgagaccu
uaaccuacuaaauaguggugcuagcauuugcugguuauccacuucuuaga
gggacuaucgguuucaagccgauggaaguuugaggcaauaacaggucugu
augcccuuaacguucugggccgcacgcgcgcuacacugacggagccagcg
agucuaaccuuggccgagaggucuugguaaucuugugaaacuccgucgug
cuggggauagagcauuguaauuauugcucuucaacgaggaauuccuagua
agcgcaagucaucagcuugcguugauuacgucccugcccuuuguacacac
cgcccgucgcuaguaccgauugaauggcuuagugaggccucaggaucugc
uuagagaagggggcaacuccaucucagagcggagaauuuggacaaacuug
gucauuuagaggaacuaaaagucguaacaagguuuccguaggugaaccug
cggaaggauca

...<<<<<.[.((((>>>>><<<<..<<<<<.....<.........<<<.
<<<..<<...<<..........<<.......>>..>>>>......<<...
.....<<<..<<.<<....<<<.....<<<.....<..<<......>>..
>......>>>........<<<<..<<....>>..>>>>.......<<<<.
........<<<..<<<....>>>....>>>.......>>>>.........
.......<.<........>>........>>>...>>>>..>>>.<<<...
.<<<..<<<<<<<<.......>>>>>>>>>>>......>>>..<<<<<<<
<....>>>>...>>>>.>>.<<.<<.<.........>>>.>>...<<...
.>>.....>>>>>>.........<<<....<<<.....>>>..>>>....
...>.......<<<<<<....<<<....>>>....>>>.>>>........
..<<..........>>.............<<<<(((....<<<<.....<
..))).>.......>>>>.>>>>...>>>>>.>>>>.........<<<((
.....<.<<...<<<.......<<<<<..<...<<<<<<<<<.....>>>
.>.>>>>>.......>..>>>>>..<<<......<<.......<<<<<<.
<<.<<.....>>..>>.>>>>>>..<<<<<<<.....>>>>>>><<<...
.<<<<.....>>>.>..>>>.....>>...<<<<<<<<<<<<<<<<<<..
..>>>>>>>>>>>>>>.>>>>..>>>...............<<<<<<.<<
...<<<<......<<<<<<.<..<<<......>>>......>.>>>>>.>
..........<<....>>...>>>>...>>>>.>>>>...>>>...>>.>
....<<<<<<<.......<<<<.<.....>.>>>>....>>>>>>>....
......<<<<<.....<<<<<<<<..<<........>>>>>>>>>>....
....<<..))>>....>>>>>.>>>.<<<......<<<......>>>...
.>>>..)))).]<<<<<.<<<<<<<.....<<<<<..<<<.<<<<<<...
..<<........>>..........<<<<<.<.....<<<<.<<.......
.<<<........>>>.......>>>>>>....<..<<<..<<<<<<<<..
...<<<.<<<<......>>...<<<......>>>...>>.>>>....<<<
<<.<<<...<<..<<<<<.<<<<<<....>>>>>>...>>>>>..>>..>
>>....<<<<<<.....>>>>>>.......>>>>>.....>>.>>>...>
>>>>>.>....>.>>>>>...>>.>>>>.>>>.....<<<<<<<.....<
<<....<<<................>>>...>>>......>>>>>>>...
...<..<.<<<<..............>>>>>...>.....>>>>>.....
<<<<<<<<.......>>>>>>>>...........>>>>>>>>>>.>>...
....<<.<..<<<..<<..<.<<<<<<<<.<<<....<<..<...<<<<<
<<.<<<<.<<<<....>>>>.>>>>.>>>>>>>...>..>>....>>>.>
>>>>>>>>..>>..>>>...>.>>..........<<<<<<<<....>>>>
>>>>.......

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4v7h Comprehensive molecular structure of the eukaryotic ribosome.
• Resolution: 8.9 Å
• Binding residue (original residue number in PDB): R67 G68 K69 S77 K79 M80 H81 R82 T83 R87 Y90 L91 H92 Y93 K96 R99 K102 R103 H104 K105 N106 V107 C128 R129 P130 K133 T134 R136 F137
• Binding residue (residue number reindexed from 1): R1 G2 K3 S11 K13 M14 H15 R16 T17 R21 Y24 L25 H26 Y27 K30 R33 K36 R37 H38 K39 N40 V41 C62 R63 P64 K67 T68 R70 F71

Gene Ontology

--> -->

UnboundLocalError

Python 3.6.8: /usr/bin/python3 Tue Nov 26 16:04:59 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1435     title=pdb2title(pdbid)

   1436     if bs.startswith("BS"):

=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)

   1438     else:

   1439         if lig3:

pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '4v7h', asym_id = 'AQ', bs = 'BS01', title = 'Comprehensive molecular structure of the eukaryotic ribosome.'

 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='4v7h', asym_id='AQ', bs='BS01', title='Comprehensive molecular structure of the eukaryotic ribosome.')

   1295         display_ec(ec,csaOrig,csaRenu)

   1296     if go:

=> 1297         display_go(go,uniprot,pdbid,asym_id)

   1298     return pubmed,uniprot

   1299 

global display_go = <function display_go>, go = '0003735,0005840,0006412', uniprot = '', pdbid = '4v7h', asym_id = 'AQ'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0003735,0005840,0006412', uniprot='', pdbid='4v7h', asym_id='AQ')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>