Structure of PDB 4v6s Chain AQ Binding Site BS01

Receptor Information

>4v6s Chain AQ (length=117) Species: 562 (Escherichia coli)

MDKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVA
ASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYH
GRVQALADAAREAGLQF

Ligand information

>4v6s Chain AA (length=120)

ugccuggcggccguagcgcgguggucccaccugaccccaugccgaacuca
gaagugaaacgccguagcgccgaugguaguguggggucuccccaugcgag
aguagggaacugccaggcau

<<<<<.<<<<.....<<<<<<<<....<<<<<<...............>>
>..>>>...>>>>>>.>>.<<.......<<<<<<<<...>>>>>>>>...
....>>...>>>>.>>>>>.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4v6s Structural characterization of mRNA-tRNA translocation intermediates.
• Resolution: 13.1 Å
• Binding residue (original residue number in PDB): M1 D2 K4 R7 I8 R10 R15 Q19 R25 H29 R30 T31 P32 R33 H34 Y36 Q38 I40 G44 S45 V47 S52 V54 Y64 N67 K68 S95 F97 Q98 H100 R102
• Binding residue (residue number reindexed from 1): M1 D2 K4 R7 I8 R10 R15 Q19 R25 H29 R30 T31 P32 R33 H34 Y36 Q38 I40 G44 S45 V47 S52 V54 Y64 N67 K68 S95 F97 Q98 H100 R102

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0008097 5S rRNA binding
• GO:0019843 rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4v6s, PDBe:4v6s, PDBj:4v6s
• PDBsum: 4v6s
• PubMed: 22467828
• UniProt: P0C018|RL18_ECOLI Large ribosomal subunit protein uL18 (Gene Name=rplR)