Structure of PDB 8oeq Chain AP Binding Site BS01 |
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>8oeq Chain 1 (length=3217)
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ugaccucaaaucagguaggacuacccgcugaacuuaagcauaucaauaag cggaggaaaagaaaccaacagggauugccucaguagcggcgagugaagcg gcaaaagcucaaauuugaaaucuggcgucuuuggcguccgaguuguaauu ugaagaagguaucuuugggcccggcucuugucuauguuccuuggaacagg acgucacagagggugagaaucccgugcgaugagaugacccgggucugugu aaaguuccuucgacgagucgaguuguuugggaaugcagcucuaagugggu gguaaauuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaa guacagugauggaaagaugaaaagaacuuugaaaagagagugaaaaagua cgugaaauuguugaaagggaagggcuugagaucagacuugguauuuugca ugcugcgguuuaccgggccagcaucgguuuggagcggcaggauaauggcg gaggaauguggcacggcuucugcuguguguuauagccucugacgauacug ccagccuagaccgaggacugcgguuuaccuaggauguuggcauaaugauc uuaagucgcccgucuugaaacacggaccaaggagucuaacgucuaugcga guguuuggguguaaaacccguacgcguaaugaaagugaacgaaggugggg gcccauuagggugcaccaucgaccgauccugauguguucggauggauuug aguaagagcauagcuguugggacccgaaagauggugaacuaugccugaau agggugaagccagaggaaacucugguggaggcucguagcgguucugacgu gcaaaucgaucgucgaauuuggguauaggggcgaaagacuaaucgaacca ucuaguagcugguuccugccgaaguuucccucaggauagcagaagcucgu aucaguuuuaugagguaaagcgaaugauuagaagucuugggguugaaaug accuuaacuuauucucaaacuuuaaauauguaagaaguccuuguugcuua auugaacguggacaauugaaugaagagcuuuuagugggccauuuuuggua agcagaacuggcgaugcgggaugaaccgaacgugaaguuaaagugccgga augcacgcucaucagacaccacaaaagguguuaguucaucuagacagccg gacgguggccauggaagucggaauccgcuaaggaguguguaacaacucac cggccgaaugaacuagcccugaaaauggauggcgcucaagcgugcuacuu auacuucaccgugauugcuguuuugacgcuuucacgaguaggcaggcgug gaggucagugacgaagccuuugcuguaaagcugggucgaacggccucuag ugcagaucuuggugguaguagcaaauauucaaaugagaacuuugaagacu gaaguggggaaagguuccaugucaacagcaguuggacauggguuagucga uccuaagagauggggaagcuccguuucaacgugcuugauuuuucaggcca accaucgaaagggaauccgguuaaaauuccggaacuuggauauggauucu ucacggcaacguaacugaauguggagacgucggcgugagcccugggagga guuaucuuuucuucuuaacagcuuaucacccuggaauugguuuauccgga gauggggucuuauggcuggaagagcgcgguaauuuugccgcguccggugc gcuuacgacgguccuugaaaauccacaggaaggaauaguuuucaugccaa gucguacucauaaccgcagcaggucuccaagguuaacagccucuaguuga uagaauaauguagauaagggaagucggcaaaauagauccguaacuucggg auaaggauuggcucuaaggaucgguuuaacgaucaacuuagaacugguac ggacaaggggaaucugacugucuaauuaaaacauagcauugugaugguca gaaagugauguugacacaaugugauuucugcccagugcucugaaugucaa agugaagaaauucaaccaagcgcggguaaacggcgggaguaacuaugacu cucuuaagguagccaaaugccucgucaucuaauuagugacgcgcaugaau ggauuaacgagauucccacugucccuaucuacuaucuagcgaaaccacag ccaagggaacgggcuuggcagaaucagcggggaaagaagacccuguugag cuugacucuaguuugacauugugaaaagacauggaggguguagaauaagu gggagcuucggcgccggugaaauaccacuaccucuauaguuuuuuuacuu auucaaugaagcggagcuggaggucaaacuccacguucuagcauuaagcc cucugggcgauccggguugaagacauugucagguggggaguuuggcuggg gcggcacaucuguuaaacgauaacgcagguguccuaagggggacucaugg agaacagaaaucuccaguagaacaaaaggguaaaaguccccuugauuuug auuuucagugugaauacaaaccaugaaaguguggccuaucgauccuuuag ucccucggaauuugaggcuagaggugccagaaaaguuaccacagggauaa cuggcuuguggcagucaagcguucauagcgacauugcuuuuugauucuuc gaugucggcucuuccuaucauaccgaagcagaauucgguaagcguuggau uguucacccacuaauagggaacgugagcuggguuuagaccgucgugagac agguuaguuuuacccuacugaugaauguuaucgcaauaguaauugaacuu aguacgagaggaaccguucauucagauaauugguuuuugcggcugucuga ucaggcaacgccgcgaagcuaccaucugcuggauuauggcugaacgccuc uaagucagaauccaugcuagaacgcgaugauuuuugcccugcacauuuua gauggauacgaauaagacuuuagucgcuggaccauagcaggcuggcaacg gugcgcuuagcggaaaggcuuugugcgcuugccggcggauagcaauguca acaugcgcggggauaaauccuuugcauacgacuuagauguacaacggagu auuguaagcaguagaguagccuuguuguuacgaucugcugagauuaagcu cuuguugucugauuugu |
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PDB | 8oeq Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement |
Resolution | 3.3 Å |
Binding residue (original residue number in PDB) | V2 N3 P5 R8 K9 T10 Y11 K13 K15 R18 K19 H20 Y28 G31 K32 A33 S34 F36 A37 Q38 G39 K40 R41 R42 R45 K46 G49 Y50 G51 G52 Q53 Q56 I57 F58 K60 A62 K63 T65 K67 V69 T79 K80 Q82 P84 K86 R87 C88 K89 K97 K98 |
Binding residue (residue number reindexed from 1) | V1 N2 P4 R7 K8 T9 Y10 K12 K14 R17 K18 H19 Y27 G30 K31 A32 S33 F35 A36 Q37 G38 K39 R40 R41 R44 K45 G48 Y49 G50 G51 Q52 Q55 I56 F57 K59 A61 K62 T64 K66 V68 T78 K79 Q81 P83 K85 R86 C87 K88 K96 K97 |
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