Structure of PDB 4v8g Chain AO Binding Site BS01

Receptor Information
>4v8g Chain AO (length=88) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHH
SHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIRG
Ligand information
>4v8g Chain AA (length=1505) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uguuggagaguuugauccuggcucagggugaacgcuggcggcgugccuaa
gacaugcaagucgugcgggccgcggggucuccguggucagcggcggacgg
gugaguaacgcgugggugaccuacccggaagagggggacaacccggggaa
acucgggcuaaucccccauguggacccgccccuugggguguguccaaagg
gcuuugcccgcuuccggaugggcccgcgucccaucagcuaguuggugggg
uaauggcccaccaaggcgacgacggguagccggucugagaggauggccgg
ccacaggggcacugagacacgggccccacuccuacgggaggcagcaguua
ggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuuggagg
aagaagcccuucgggguguaaacuccugaacccgggacgaaacccccgac
gaggggacugacgguaccgggguaauagcgccggccaacuccgugccagc
agccgcgguaauacggagggcgcgagcguuacccggauucacugggcgua
aagggcguguaggcggccuggggcgucccaugugaaagaccacggcucaa
ccgugggggagcgugggauacgcucaggcuagacggugggagaggguggu
ggaauucccggaguagcggugaaaugcgcagauaccgggaggaacgccga
uggcgaaggcagccaccugguccacccgugacgcugaggcgcgaaagcgu
ggggagcaaaccggauuagauacccggguaguccacgcccuaaacgaugc
gcgcuaggucucugggucuccugggggccgaagcuaacgcguuaagcgcg
ccgccuggggaguacggccgcaaggcugaaacucaaaggaauugacgggg
gcccgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaagaa
ccuuaccaggccuugacaugcuagggaacccgggugaaagccuggggugc
cccgcgaggggagcccuagcacaggugcugcauggccgucgucagcucgu
gccgugagguguuggguuaagucccgcaacgagcgcaacccccgccguua
guugccagcgguucggccgggcacucuaacgggacugcccgcgaaagcgg
gaggaaggaggggacgacgucuggucagcauggcccuuacggccugggcg
acacacgugcuacaaugcccacuacaaagcgaugccacccggcaacgggg
agcuaaucgcaaaaaggugggcccaguucggauuggggucugcaacccga
ccccaugaagccggaaucgcuaguaaucgcggaucagccaugccgcggug
aauacguucccgggccuuguacacaccgcccgucacgccaugggagcggg
cucuacccgaagucgccgggagccuacgggcaggcgccgaggguagggcc
cgugacuggggcgaagucguaacaagguagcuguaccggaaggugcggcu
ggauc
.......<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..
<<<.<<<..<<<..<<.<<<<<<<<<...>>>>>>>>>.>>>>>......
<<.......<<<<<<<<..<<...<<<<<<<.<<<<<...<<<<<<....
..>>>>>.>...>>>>>...<<<<<.<<<<<....>>>>>.>>>>>..<<
<<...>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<<.
......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>
>.>>.<<<<<.<.........>>>>>>.<<<<<..>>>>>...>>>>>>>
........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<.
.....<<<<....>>>>.....>>>>....<<<<<......<.<<<<...
..>>>>..>.......>>>>>......<<<<<(((...<<<<<.....<<
.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<((.
....<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<.....
>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<<
....<<<<<<<.<..<<<......>>>.....>.>>>>>>>.........
..<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<
<<...<<...<<<<.<.....>.>>>>...>>>>>>>>..........<<
<<<<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....>>>>>
>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<.<<
<<<<<.<<..<<<<<..<<<<<<<<<<.......<........>......
.....<<<<<<<......<<<<<<<<..<..<<<<....>>>>.>..<..
.<......>...>>>>>>>>>..<..<<<..<<<<<<.......<<<<<<
<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<
<...<...<<<.....>>>>.....>>>>>>>.....<<<<<....>>>>
>........>>>>.........>>>...>>>>>>.>....>>>>>>>...
>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>.
.>>....>>>.....>>>>>>>...........<<<<<<<........>>
>>>>>..........>>>>>.....<<<<<<<..........>>>>>>>.
.....>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<
<<<<<<<<...<.<<<<.....<<....>>..>>>>.>..>>>>>>>>>>
>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>
.....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4v8g How hibernation factors RMF, HPF, and YfiA turn off protein synthesis.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		P2 K8 F18 T22 G23 S24 Q28 L31 R35 R38 H42 H46 K48 D49 H50 H51 S52 R54 M59 R64 Y69 R72
Binding residue
(residue number reindexed from 1)		P1 K7 F17 T21 G22 S23 Q27 L30 R34 R37 H41 H45 K47 D48 H49 H50 S51 R53 M58 R63 Y68 R71
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4v8g, PDBe:4v8g, PDBj:4v8g
PDBsum4v8g
PubMed22605777
UniProtQ5SJ76|RS15_THET8 Small ribosomal subunit protein uS15 (Gene Name=rpsO)

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