Structure of PDB 7n8b Chain AN Binding Site BS01 |
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| >7n8b Chain A1 (length=3156)
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uugaccucaaaucagguaggaguacccgcugaacuuaagcauaucaauaa
gcggaggaaaagaaaccaaccgggauugccuuaguaacggcgagugaagc
ggcaaaagcucaaauuugaaaucugguaccuucggugcccgaguuguaau
uuggagagggcaacuuuggggccguuccuugucuauguuccuuggaacag
gacgucauagagggugagaaucccguguggcgaggagugcgguucuuugu
aaagugccuucgaagagucgaguuguuugggaaugcagcucuaagugggu
gguaaauuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaa
guacagugauggaaagaugaaaagaacuuugaaaagagagugaaaaagua
cgugaaauuguugaaagggaagggcauuugaucagacaugguguuuugua
uuucacuggccagcaucaguuuugguggcaggauaaauccauaggaaugu
agcuugccucgguaaguauuauagccugugggaauacugccagcugggac
ugaggacugcgacguaagucaaggaugcuggcauaaugguuauaugccgc
ccgucuugaaacacggaccaaggagucuaacgucuaugcgaguguuuggg
uguaaaacccauacgcguaaugaaagugaacguagguuggggccucgcaa
gaggugcacaaucgaccgauccugaugucuucggauggauuugaguaaga
gcauagcuguugggacccgaaagauggugaacuaugccugaauaggguga
agccagaggaaacucugguggaggcucguagcgguucugacgugcaaauc
gaucgucgaauuuggguauaggggcgaaagacuaaucgaaccaucuagua
gcugguuccugccgaaguuucccucaggauagcagaagcucguaucaguu
uuaugagguaaagcgaaugauuagagguuccggggucaccuugaccuauu
cucaaacuuuaaauauguaagaaguccuuguuacuuaauugaacguggac
auuugaaugaagagcuuuuagugggccauuuuugguaagcagaacuggcg
augcgggaugaaccgaacguagaguuaaggugccggaauacacgcucauc
agacaccacaaaagguguuaguucaucuagacagccggacgguggccaug
gaagucggaauaggaguguguaacaacucaccggccgaaugaacuagccc
ugaaaauggauggcgcucaagcguguuaccuauacucuaccgucaggguu
gauaugaugcccugacgaguaggcaggcguggaggucagugacgaagccu
agaccguaaggucgggucgaacggccucuagugcagaucuuggugguagu
agcaaauauucaaaugagaacuuugaagacugaaguggggaaagguucca
cgucaacagcaguuggacguggguuagucgauccuaagagauggggaagc
uccguuucaaaggccugauuuuaugcaggccaccaucgaaagggaauccg
guuaagauuccggaaccuggauauggauucuucacgguaacguaacugaa
uguggagacgucggcgcgagcccugggaggaguuaucuuuucuucuuaac
agcuuaucaccccggaauugguuuauccggagauggggucuuauggcugg
aagaggccagcaccuuugcuggcuccggugcgcuugugacggcccgugaa
aauccacaggaaggaauaguuuucaugccaggucguacugauaaccgcag
caggucuccaaggugaacagccucuaguugauagaauaauguagauaagg
gaagucggcaaaauagauccguaacuucgggauaaggauuggcucuaagg
gucggguacgaucaacuuagaacugguacggacaaggggaaucugacugu
cuaauuaaaacauagcauugcgauggucagaaagugauguugacgcaaug
ugauuucugcccagugcucugaaugucaaagugaagaaauucaaccaagc
gcggguaaacggcgggaguaacuaugacucucuuaagguagccaaaugcc
ucgucaucuaauuagugacgcgcaugaauggauuaacgagauucccacug
ucccuaucuacuaucuagcgaaaccacagccaagggaacgggcuuggcag
aaucagcggggaaagaagacccuguugagcuugacucuaguuugacauug
ugaagagacauaguuucuuuacuuauucaaugaagcggagcuggaauuca
uuuuccacguucuagcauucaaggucccauucggggcugauccggguuga
agacauugucagguggggaguuuggcuggggcggcacaucuguuaaacga
uaacgcagauguccuaaggggggcucauggagaacagaaaucuccaguag
aacaaaaggguaaaagcccccuugauuuugauuuucagugugaauacaaa
ccaugaaaguguggccuaucgauccuuuagucccucggaauuugaggcua
gaggugccagaaaaguuaccacagggauaacuggcuuguggcagucaagc
guucauagcgacauugcuuuuugauucuucgaugucggcucuuccuauca
uaccgaagcagaauucgguaagcguuggauuguucacccacuaauaggga
acgugagcuggguuuagaccgucgugagacagguuaguuuuacccuacug
augaauguuaccgcaauaguaauugaacuuaguacgagaggaacaguuca
uucggauaauugguuuuugcggcugucugaucaggcauugccgcgaagcu
accauccgcuggauuauggcugaacgccucuaagucagaauccaugcuag
aacgcggugauuucuuugcuccacacaauauagauggauacgaauaaggc
guccuuguggcgucgcugaaccauagcaggcuagcaacggugcacuuggc
ggaaaggccuugggugcuugcuggcgaauugcaaugucauuuugcguggg
gauaaaucauuuguauacgacuuagauguacaacgggguauuguaagcag
uagaguagccuuguuguuacgaucugcugagauuaagccuuuguugucug
auuugu |
........................<<<<<<.....<......>......>
>>>>.>...<.....<<....>>..<<<<<......<<.....>>.....
>>>>>..<<<...........<<.<<<<<<...>>>>>>.>>........
.....<<<<<<.<<<<<.<<.<<<<<<<<<<<<<....<<<<......>>
>>.(.......<<<......)>>>..>.>>>>>>>>..>>>>>>......
>>>>>>>>>>>........<<<<<<<........>>>>>>>.....<<<<
<..((((((>>>>>..>>>....>..........................
...<<....>>...............<<<<....>>>>............
......................<<<<<.<<<<<.<...............
........<<<<<<<.<<<<<<<<<<<<<<<.....<<<<<<<<<.....
.<<<<........>>>>.......>>>>>>>.>.>.>>>>>.>>>>>>>>
>>........<<<....>>>.....>>>>>>>....>>>>>>.>>>>>..
<<<<........>>>><<<<<<....<<<<<<.<<<<<<..<<<...<<<
<.....>>>>...>>>...<<....>>.......<<<<<..<<<<<....
>>>>>...>>>>>.<<<<<<<<...<<....>>...>>>.>>>.>>....
>>>>>>.>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<...
.<<<<<<<....>>>>>>>.....>>>...<<<..<<.<<........>>
>>.>>>....>>>>>>>>>...<<.......>>......>>>>>>...>.
.>.>>..<<<<<<....<.<<<....>>>.><<<<<<<<<<...<<<.<<
<<<<<.....<<<....<<<....<<<.................>>>...
.>>>..>.>>.....>>>>>...<<<<.<<<<.<......>>>>>.>>>>
.....>>>>>.>>>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>.
...<<<......>>>...<<<<<<<..<<<<(((.....<<<<<<.....
<<..........<<<.<<<<<<<<<<.........<<<............
..............................>>>.....>>>>>>>>>>>>
>..........))).>>...>>>>>>.>>>>..>>>>>>><<<<<<<<<.
........>>>>>>>>>....>>>>>><.<<<<<<<<.<<......<<<<
.<<<<....>>>>>>>>...>>>>>>>>>>..>.....>>>>>><<....
.<<.....<<<<<<.......>>>>>><<<<.....<<<<<.<<...<<<
<<<...<<.....>>.>>>>>>....((<<<<<<...<<....<<<....
>>>........<<<<............>>>>....>>....>>...<<<<
<........>>>>>))<<<<.<<<<<<......<<<....>>>.......
<<<<<<...<<<<.<<<<<<<.<<<<<<<<<<..[[[..>>>>>><...<
<<<<....<<<<<<....<<<.....>>>....>>>>>>.....>>>>>.
...><<<<<<<......>>>>>>>>>>>...>>>>>>>.>>>>.......
..>>>>>>............>>.>>>>>>>>>>>>..>>.....<<....
..>>>>>>>.<<<<.....>>>>..>>>>..<<<<.....<<<<<<<.<<
.........<.....<<<<<...............>>>>><<.<<<<<<<
<<<<....>>>>>..>>>>>>.>>............<<<<<<<<<..<<<
.........>>>..<<<<<<<....<<<<.....>>>>......>>>>>>
>...<<..<<<..<<<<<<.<...<<.....<<<<....>>>>.....>>
.>>>>>..>>>>><<<<...........>>>>........<.........
..<<<<<.......>>>>>.....>.....>>....>>.>>>>>>>..>.
.>>.>>>>>>>..>>>>>>....>>....<<<<<........>>>>>...
.<<<<<..<<<.<<......<<<<.<<<<<<..<<<<<.<<<<<<<<..<
<<<<.............>>>>>...<<<<<.....<<<<..<<<......
....>>>...............<<<<<<....>>>>>>..>>>>..>>>>
>.....>>>>>>>>..>>>>>...<<<.....>>>..<<<<<<.......
....>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>....
.<<...(((>>....>>>>>>>...<<<.<<<<<.......>>>>.>>>>
.<<<....>>>.>>)))......<<<<<<<..<<<<.))))))>>>>>>>
>>>>.........>>>>..>>>>>>.......<<.<...<<<<<<...<<
.......>>...>>>>>>....>.>.>.......<<<<<.<<<<<<..<.
<<<<<<<......>>>>>>>...>.<<<.........>>>.....>>>>>
..>...>>>.>>....<<<<<<<....>>>.>>>>....>>..>>>.>>>
>>....<<<<<<<<..<<<<...<<<<<<...............>>>>>>
..<<<<<...<<<<....<<<<<<<<<<]]].>>>>>..>>>>>...>>>
>..>>>>>.<<<<...<<<<<...........>>>>>...>>>>.>>>>.
...>>>>>>>>.......<<<<<<.<<<.<<....<<..........<<<
<<<.....>>>>>>......>>.......<<<<<<...<<<<<.<..<<<
......>>>..>.>>>>>.>>>>>>.............>>.>>>.>>>>>
>..<<<<<.<.............>.....<<<<<<<<<.<<<....<<<<
....<<<<<......>>>>>...>>>>...>>>....>>>>.>>>>>..>
>>>>.. |
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| PDB | 7n8b CryoEM structures of pseudouridine-free ribosome suggest impacts of chemical modifications on ribosome conformations. |
| Resolution | 3.05 Å |
Binding residue
(original residue number in PDB) | G2 Y4 K5 E8 R12 K14 Q15 R20 R24 W28 R31 N34 V35 A40 R41 R44 K47 R49 R50 L51 K54 A55 K56 Q57 R67 R68 G69 N70 R71 K72 R73 P74 P76 K77 G78 Y81 G82 K83 P84 T85 N86 Q87 N90 E91 K93 Y94 Q95 R96 S97 R105 R108 N112 W120 S125 Y127 K128 Q138 H139 K140 A141 R144 R147 W150 P154 V155 H156 K157 H158 A161 R162 L164 A166 K169 K170 S171 R172 I174 K176 H178 K179 F180 N181 N182 R187 R188 K189 W191 K192 R193 Q194 S198 W200 R201 Y202 R203 K204 |
Binding residue
(residue number reindexed from 1) | G1 Y3 K4 E7 R11 K13 Q14 R19 R23 W27 R30 N33 V34 A39 R40 R43 K46 R48 R49 L50 K53 A54 K55 Q56 R66 R67 G68 N69 R70 K71 R72 P73 P75 K76 G77 Y80 G81 K82 P83 T84 N85 Q86 N89 E90 K92 Y93 Q94 R95 S96 R104 R107 N111 W119 S124 Y126 K127 Q137 H138 K139 A140 R143 R146 W149 P153 V154 H155 K156 H157 A160 R161 L163 A165 K168 K169 S170 R171 I173 K175 H177 K178 F179 N180 N181 R186 R187 K188 W190 K191 R192 Q193 S197 W199 R200 Y201 R202 K203 |
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| Enzyme Commision number |
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