Structure of PDB 6xu8 Chain AN Binding Site BS01

Receptor Information
>6xu8 Chain AN (length=150) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRMHAPGKGISQSALPYRRTVPSWLKLNADDVKEQIKKLGKKGLTPSKIG
IILRDSHGVAQVRFVNGNKILRIMKSVGLKPDIPEDLYHMIKKAVAIRKH
LERNRKDKDGKFRLILVESRIHRLARYYKTKSVLPPNWKYESSTASALVA
Ligand information
>6xu8 Chain B2 (length=1936) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auucugguugauccugccaguaguuauaugcuugucucaaagauuaagcc
augcaugucuaaguacacacgaauuaaaagugaaaccgcaaaaggcucau
uauaucaguuaugguuccuuagaucguuaacaguuacuuggauaacugug
guaauucuagagcuaauacaugcaauuaaaacaugaaccuuaugggacgu
gugcuuuuauuaggcuaaaaccaagcgaucgcaagaucguuauauugguu
gaacucuagauaacaugcagaucguauggucuuguaccgacgacagaucu
uucaaaugucugcccuaucaacuuuugaugguaguaucuaggacuaccau
gguugcaacggguaacggggaaucaggguucgauuccggagagggagccu
gagaaacggcuaccacaucuaaggaaggcagcaggcgcguaaauuaccca
cucccagcucggggagguagugacgaaaaauaacaauacaggacucauau
ccgaggcccuguaauuggaaugaguacacuuuaaauccuuuaacaaggac
caauuggagggcaagucuggugccagcagccgcgguaauuccagcuccaa
uagcguauauuaaaguuguugcgguuaaaacguucguaguugaacuugug
cuucauacggguaguauacuauaccuuuauguauguaagcguauuaccgg
uggaguucuuauaugugaucauauguuccuccuauuuaaaaaccugcauu
agugcucuuaaacgaguguuauugugggccgguacuauuacuuugaacaa
auuagagugcuuaaagcaggcuucaaaugccugaauauucugugcauggg
auaaugaaauaagaccucuguucugcuuucauugguuuucagaucaagag
guaaugauuaauagaagcaguuugggggcauuaguauuacgacgcgagag
gugaaauucuuggaccgucguaagacuaacuuaagcgaaagcauuugcca
aagauguuuucauuaaucaagaacgaaaguuagagguucgaaggcgauca
gauaccgcccuaguucuaaccauaaacgaugccagcuagcaauugggugu
agcuacuuuuauggcucucucagucgcuuccgggaaaccaaagcuuuuug
ggcuccgggggaaguaugguugcaaagcugaaacuuaaaggaauugacgg
aagggcaccaccaggaguggagccugcggcuuaauuugacucaacacggg
aaaacuuaccaggucgaacauaaguguguaagacagauugauagcucuuu
cucgaaucuaugggugguggugcauggccguucuuaguucguggagugau
uugucugguuaauuccgauaacgaacgagacucaaauauauuaaauagau
aucuucaggauuauggugcugaagcuuauguagccuucauuauuguguuu
gaauguguuuauguaaguggagccguaccuguugguuugucccauuauaa
ggacacuagcuucuuaaauggacaaauugcgucuagcaauaaugagauug
agcaauaacaggucugugaugcccuuagauguccugggcugcacgcgcgc
uacaaugaaaguaucaacguguauuuccuagaccgagagguccggguaaa
ccgcugaaccacuuucaugcuugggauugugaacugaaacuguucacgau
gaacuuggaauucccaguaagugugagucauuaacucgcauugauuacgu
cccugcccuuuguacacaccgcccgucgcuacuaccgauugaauuauuua
gugaggucuccggacgugaucacugugacgccuugcguguuacgguuguu
ucgcaaaaguugaccgaacuugauuauuuagaggaaguaaaagucguaac
aagguuuccguaggugaaccugcggaaggaucauua
...<<<<<.{.((((>>>>><<<<.<<<<<<...<.<<..<......<<<
.<<<..<<....<<....<<.........>>...>>.>>......<<...
.....<<<.<<<..<<....<<<<..............<<.....<<.<<
<.....>>>.>>......>>...........<<<<............>>>
>.<<..<<<<<.....(((...((..<<<<....>>>>........<...
.....>..>>>>>...>>...<...................>....>>>>
...>>>>>.>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>
>>>......>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<..
........>>>.>>.<.<<....>>.>...>>>>>>.........<<<..
..<<<.....>>>..>>>..>...>>.>.....<.<<<<<...<<<....
..>>>....>>>>..>.>.....<<.................>>......
...<<<<<((......<<<<.....<<..))>>.......>>>>.>>>>>
..>>>>>>>>>>.........<<<[[.....<<<<...<<<.<<.....<
<<<...<<......................>>....>>>>......<<..
..................................................
..............................>>....<<<<<<.<<.....
..<<...<.......>..<<<.......>>>....>>.......>>.>>.
.>>>>..........................))...)))...........
.......>>....<<<<..<.<<...<<<<..<<..<<<<<<<<...<<<
......>>>......>>>>>>>.>.>>.......<<....>>...>>>>.
..>>>.>.>>>...>>>...>>>>....<<<<<<<...<...<<<<.<..
...>.>>>>...>>>>>>>>..........<<<.<<.<<<.<<<<<<...
.<<<........>>>...>>>>>>.>>>...<<..]]>>...>>......
>>>.>>>.<<<......<<<......>>>....>>>..)))).}<<....
<<<<<<<..<<..<<<<<.<<<<.<<<<<<......<<........>>..
........<<<<......................<<<........>>>..
...............<<.<<<...<.<<<<<.....<<<.<.........
.....................>.>>>....<<<<..<<..<.<.......
.<.........<..<...................................
.......................>..>.......>...<<<<........
>>>>..........>.>.>>............................>>
>>.....>>.>>>.....>.>>>>>........>>>>...>>.>>>>.>>
>.>...<<<<<<..............<<<.<<<<....>>>>.>>>....
..........>>>>>>.........<<.....<..........>....>>
.........>>>>>.....<<<<<<<<.......>>>>>>>>......>>
...>>>>>>>....>>....<..<<.<..<<<<.<<....<<<<.<<<.<
<<..<<<<..<....<<<<.<<....<<<.........>>>.....>>..
>>>>....>..>>>>..>>>.>>>.>>>>...>>.>>>>...>.>>...>
.....<<<<<<<<<....>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6xu8 Ribosome heterogeneity in Drosophila melanogaster gonads through paralog-switching.
Resolution3.0 Å
Binding residue
(original residue number in PDB)
G2 R3 M4 H5 G8 K9 G10 I11 S12 Q13 S14 A15 P17 P47 S48 K49 G51 I52 R55 A61 Q62 R64 N69 K70 I71 L72 R73 K76 S77 M91 K94 H101 R106 K107 D108 K109 D110 K112 F113 R114 I116 S120 R121 R124 Y128
Binding residue
(residue number reindexed from 1)
G1 R2 M3 H4 G7 K8 G9 I10 S11 Q12 S13 A14 P16 P46 S47 K48 G50 I51 R54 A60 Q61 R63 N68 K69 I70 L71 R72 K75 S76 M90 K93 H100 R105 K106 D107 K108 D109 K111 F112 R113 I115 S119 R120 R123 Y127
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0070181 small ribosomal subunit rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0000228 nuclear chromosome
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6xu8, PDBe:6xu8, PDBj:6xu8
PDBsum6xu8
PubMed34283226
UniProtQ03334|RS13_DROME Small ribosomal subunit protein uS15 (Gene Name=RpS13)

[Back to BioLiP]