Structure of PDB 4v49 Chain AM Binding Site BS01

Receptor Information

>4v49 Chain AM (length=125) Species: 562 (Escherichia coli)

ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEA
EVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQ
RTRTNARTRKGPRKTVAGKKKAPRK

Ligand information

>4v49 Chain AA (length=1527)

uggagaguuugauccuggcucagggugaacgcuggcggcgugccuaagac
augcaagucgugcggauacgcgcggccccuuggggccgugcgucagcggc
ggacgggugaguaacgcgugggugaccuacccggaagagggggacaaccc
ggggaaacucgggcuaaucccccauguggacgcaaguccaaagggggaag
ccuucgggucccccgcuuccggaugggcccgcgucccaucagcuaguugg
ugggguaauggcccaccaaggcgacgacggguagccggucugagaggaug
gccggccacaggggcacugagacacgggccccacuccuacgggaggcagc
aguuaggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuu
ggaggaagaagcccuucgggguguaaacuccugaacccgggacgaaacca
gggccacucauacuggcucugacugacgguaccgggguaauagcgccggc
caacuccgugccagcagccgcgguaauacggagggcgcgagcguuacccg
gauucacugggcguaaagggcguguaggcggccuggggcgucccauguga
aagaccacggcucaaccgugggggagcgugggauacgcucaggcuagacg
gugggagagggugguggaauucccggaguagcggugaaaugcgcagauac
cgggaggaacgccgauggcgaaggcagccaccugguccacccgugacgcu
gaggcgcgaaagcguggggagcaaaccggauuagauacccggguagucca
cgcccuaaacgaugcgcgcuaggucucuggcggcucaaccgcugggggcc
gaagcuaacgcguuaagcgcgccgccuggggaguacggccgcaaggcuga
aacucaaaggaauugacgggggcccgcacaagcgguggagcaugugguuu
aauucgaagcaacgcgaagaaccuuaccaggccuugacaugcuagggaac
ccgggugaaagccuggggugccuucgggagcccuagcacaggugcugcau
ggccgucgucagcucgugccgugagguguuggguuaagucccgcaacgag
cgcaacccccgccguuaguugccagcgguucggccgggcacucuaacggg
acugcccgcgaaagcgggaggaaggaggggacgacgucuggucagcaugg
cccuuacggccugggcgacacacgugcuacaaugcccacuacaaagcgau
gccacccggcaacggggagcuaaucgcaaaaaggugggcccaguucggau
uggggucugcaacccgaccccaugaagccggaaucgcuaguaaucgcgga
ucagccaugccgcggugaauacguucccgggccuuguacacaccgcccgu
cacgccaugggagcgggcucuacccgaagucgccggguaaccuacgggaa
gcaggcgccgaggguagggcccgugacuggggcgaagucguaacaaggua
gcuguaccggaaggugcggcuggauca

....<<<<....[[...>>>>.<<<<.<<<<<.<<<<<<<<<..<..<<<
.<<<..<<<..<<.<<..<<<<<<<<<<....>>>>>>>>>>>>.>>>>>
......<<.......<<<<<<<<..<<...<<<<<<<.<<<<<....<<<
<<<....>>>>>>.....>>>>>...<<<<<....>>>>>..<<<<<<..
<<....>>>>>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<
<<<<.......>>>>>>>>>>>......>>>..<<<<<<<<..[.>>>>.
..>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>
>>>>>........<<<....<<<<....>>>>..>>>..>>.>>>>>>>.
<<<<......<<<<....>>>>.....>>>>....<<<<<........<<
<<<<<<.......>>>>>>>>..........>>>>>......<<<<<(((
...<<<<<.....<<.)))>>.......>>>>>>>>>>..>>>>>>>>>.
......]..<<<((.....<<<<...<<<.<<<<<<<.<<<<<<<<<<..
....<<<<<<.....>>>>>>....>>>>>>>>..>>>>>>>>>...<<<
<<<<<...<<<<<<<....<<<<<<<.<..<<<......>>>.....>.>
>>>>>>...........<<....>>.>>>>>>>..>>>>>.>>>...>>>
...>>>>....<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>
>>>..........<<<<<<..<<<<<<<<<<<<.....>>>>>>>>>>>>
...<<..))>>.....>>>>>>.>>>.<<<......<<<<....>>>>..
..>>>....]]..<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<..
....<<........>>..........<<<<<<<......<<<<<<<<..<
<<<<<<....>>>>>>>...<<....>>..>>>>>>>>.<<<.<<<..<<
<<<<.......<<<<<<<<<....>>>..<<<<......>>>>..>>>>>
>.....<<<<.<<<<<<<...<...<<<.....>>>.>....>>>>>>>.
....<<<<<....>>>>>........>>>>.........>>>...>>>>>
>>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<..
<<..<<<<....>>>>..>>....>>>.....>>>>>>>......<....
<<<<<<<........>>>>>>>....>.....>>>>>>....<<<<<<<.
.........>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.
<.<<<<.<<...<<<<<<<<<<<<<...<.<<<<......<<....>>..
...>>>>.>..>>>>>>>>>>>>>...>>.>>>>..>.>>...>.....<
<<<<<<<<....>>>>>>>>>......

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4v49 X-ray Crystal Structures of the WT and a Hyper-Accurate Ribosome From Escherichia Coli
• Resolution: 8.7 Å
• Binding residue (original residue number in PDB): R14 V17 Y23 G24 I25 G26 A28 R29 R44 R88 R91 L96 V98 R99 Q101 R102 T103 R104 T105 N106 A107 R108 T109 K111 R114 K115 T116 V117 K120 A123 R125 K126
• Binding residue (residue number reindexed from 1): R13 V16 Y22 G23 I24 G25 A27 R28 R43 R87 R90 L95 V97 R98 Q100 R101 T102 R103 T104 N105 A106 R107 T108 K110 R113 K114 T115 V116 K119 A122 R124 K125

Gene Ontology

--> -->

UnboundLocalError

Python 3.6.8: /usr/bin/python3 Tue Apr 29 22:47:06 2025

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1435     title=pdb2title(pdbid)

   1436     if bs.startswith("BS"):

=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)

   1438     else:

   1439         if lig3:

pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '4v49', asym_id = 'AM', bs = 'BS01', title = 'X-ray Crystal Structures of the WT and a Hyper-Accurate Ribosome From Escherichia Coli'

 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='4v49', asym_id='AM', bs='BS01', title='X-ray Crystal Structures of the WT and a Hyper-Accurate Ribosome From Escherichia Coli')

   1295         display_ec(ec,csaOrig,csaRenu)

   1296     if go:

=> 1297         display_go(go,uniprot,pdbid,asym_id)

   1298     return pubmed,uniprot

   1299 

global display_go = <function display_go>, go = '0003676,0003723,0003735,0005840,0006412', uniprot = '', pdbid = '4v49', asym_id = 'AM'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0003676,0003723,0003735,0005840,0006412', uniprot='', pdbid='4v49', asym_id='AM')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>