Structure of PDB 7toq Chain AL25 Binding Site BS01

Receptor Information
>7toq Chain AL25 (length=119) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAM
KKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAY
VRLAPDYDALDVANKIGII
Ligand information
>7toq Chain A25S (length=3649) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgcgaccucagaucagacguggcgacccgcugaauuuaagcauauuaguc
agcggaggagaagaaacuaaccaggauucccucaguaacggcgagugaac
agggaagagcccagcgccgaauccccgccccgcggcggggcgcgggacau
guggcguacggaagacccgcuccccggcgccgcucguggggggcccaagu
ccuucugaucgaggcccagcccguggacggugugaggccgguagcggccc
ccggcgcgccgggcccgggucuucccggagucggguugcuugggaaugca
gcccaaagcgggugguaaacuccaucuaaggcuaaauaccggcacgagac
cgauagucaacaaguaccguaagggaaaguugaaaagaacuuugaagaga
gaguucaagagggcgugaaaccguuaagagguaaacgggugggguccgcg
caguccgcccggaggauucaacccggcggcgcgguccggccgugucggcg
gcccggcggaucucccgcucccgucggcgggggaccgucccccgaccggc
gaccggccgccgccgggcgcauuuccaccgcggcggugcgccgcgaccgg
cuccgggacggcugggaaggccccggcggggaagguggcccgggggcccc
ggguguuacagccccgccccggcagcagcagcucgccgaaucccggggcc
gagggagcgagacccgugcgccgcgcucuccccccucgggggggccgggc
caccccucccacggcgcgaccgcuggggcggacuguccagugcgccccgg
gcgggucgcgccgucgggcccggggggccacgcgucccccgcgagcgcac
ggggucggcggcgaugucggcuacccacccgacccgucuugaaacacgga
ccaaggagucuaacacgugcgcgagucgggggcucgcacgaaagccgccg
uggcgcaaugaaggugaaggccggcgcgcucgccggccgaggugggaucc
cgaggcaguccgccgagggcgcaccaccggcccgucucgcccgccgcgcc
ggggagguggagcacgagcgcacguguuaggacccgaaagauggugaacu
augccugggcagggcgaagccagaggaaacucugguggagguccguagcg
guccugacgugcaaaucggucguccgaccuggguauaggggcgaaagacu
aaucgaaccaucuaguagcugguucccuccgaaguuucccucaggauagc
uggcgcucuccgcaguuuuauccgguaaagcgaaugauuagaggucuugg
ggccgaaacgaucucaaccuauucucaaacuuuaaauggguaagaagccc
ggcucgcugguguggagccgggcguggaaugcgagugccuagugggccac
uuuugguaagcagaacuggcgcugcgggaugaaccgaacgccggguuaag
gcgcccgaugccgacgcucaucagaccccagaaaagguguugguugauau
agacagcaggaugguggccauggaagucggaauccgcuaaggagugugua
acaacucaccugccgaaucaacuagcccugaaaauggauggcgcuggagc
gucgggcccauacccggccgucgccggcagucggcagagcgagaaagaga
guggcgcggacgcuacgccgcgacgaguaggagggccgcugcggugagcc
uugaagccuagggcgcgggcccggguggagccgccgcaggugcagaucuu
ggugguaguagcaaauauucaaacgagaacuuugaaggccgaaguggaga
aggguuccaugugaacagcaguugaacaugggucagucgguccugagaga
ugggcgagcgccguuccgaagggacgggcgauggccuccguugcccucgg
ccgaucgaaagggagucggguucagauccccgaauccggaguggcggaga
ugggcgccgcgaggcguccagugcgguaacgcgaccgaucccggagaagc
cggcgggagccccggggagaguucucuuuucuuugugaagggcagggcgc
ccuggaauggguucgccccgagagaggggcccgugccuuggaaagcgucg
cgguuccggcggcguccggugagcucucgcuggcccuugaaaauccgggg
gagaggguguaaaucucgcgccgggccguacccauauccgcagcaggucu
ccaaggugaacagccucuggcauguuggaacaauguagguaagggaaguc
ggcaagccggauccguaacuucgggauaaggauuggcucuaagggcuggg
ucggucgcggccggcgccuagcagccgacuuagaacuggugcggaccagg
ggaauccgacuguuuaauuaaaacaaagcaucgcgaaggcccgcggcggg
uguugacgcgaugugauuucugcccagugcucugaaugucaaagugaaga
aauucaaugaagcgcggguaaacggcgggaguaacuaugacucucuuaag
guagccaaaugccucgucaucuaauuagugacgcgcaugaauggaugaac
gagauucccacugucccuaccuacuauccagcgaaaccacagccaaggga
acgggcuuggcggaaucagcggggaaagaagacccuguugagcuugacuc
uagucuggcacggugaagagacaugagagguguagaauaagugggaggcc
ggccgccggugaaauaccacuacucugaucguuuuuucacugacccggug
aggcgggggggcgagccccgaggggcucucgcuucuggcgccaagcgccc
ggccgcgcgccggccgggcgcgacccgcuccggggacagugccagguggg
gaguuugacuggggcgguacaccugucaaacgguaacgcagguguccuaa
ggcgagcucagggaggacagaaaccucccguggagcagaagggcaaaagc
ucgcuugaucuugauuuucaguacgaauacagaccgugaaagcggggccu
cacgauccuucugaccuuuuggguuuuaagcaggaggugucagaaaaguu
accacagggauaacuggcuuguggcggccaagcguucauagcgacgucgc
uuuuugauccuucgaugucggcucuuccuaucauugugaagcagaauuca
ccaagcguuggauuguucacccacuaauagggaacgugagcuggguuuag
accgucgugagacagguuaguuuuacccuacugaugauguguuguugcca
ugguaauccugcucaguacgagaggaaccgcagguucagacauuuggugu
augugcuuggcugaggagccaauggggcgaagcuaccaucugugggauua
ugacugaacgccucuaagucagaaucccgcccaggcggaacgauacggca
gcgccggagccucgguuggccucggauagccggucccccgcgggguccgg
ugcggagagcccuucgucccgggaaacggggcggccggaaagggggccgc
ccucucgcccgucacgcaccgcacguucguggggaaccuggcgcuaaacc
auucguagacgaccugcuucugggucgggguuucguacguagcagagcag
cucccucgcugcgaucuauugaaagucagcccucgacacaaggguuugu
.........................<<<<<<<....<......>.....>
>>>>>.>.........<<....>>..<<<<<<.....<<.....>>....
>>>>>>..[[[...<<<<...<<<<<<<<<<<...>>>>>>>.>>>>...
..>>>>...<<<<<<<<<....<<<<<<<<.<......<<<<<<<<....
<<<<......>>>>.....((......<<<.....))>>>...>.>>>>>
>>..>>>>>>>>>...>>>>>>>>>.......<<<<<<<........>>>
>>>>.....(((((..<<<<<<)))))..]]]..................
................<<....>>...............<<<......>>
>..................................<<<<<<<<..<<<.<
<...<<<<<<<<.<<<.....<<<<<<<<<<....<<<<<<<.<<<<<.<
<....<<<<.<<<<<<<<<......>>>>>>>>>>>>>>>>>.>>>>>>>
...>>>.>>>>>>>>>>......>>>.>>>.>>>>>...<<<<<<<<<<<
<<<<<<<<<<<<...<<..<<<..<<<<<<<......<<<<<<<<.>>>>
>>>>.......>>>>>>>..>>>.........>>>>>>..>>>>>>>>>>
>.....<<.......>>.........<...<<<<<<..>>>>>>....<<
<...<<.<<<<<<<<<<<<<<<<<<<<<<<.<<<<..>>>>.>>>>>>.>
>>.>>>>>>>>>>>.>>>...>>.>>.>................>.....
...>>>.>>>>>...>>>>>...>>>>>>>>..<<<<........>>>><
<<<<<....<<<<<<<<<<<<<..<<<...<<<<........>>>>....
.>>>...<<....>>...<<<<<<<<....>>>>>>>>..<<<<<...<<
<..<<.{.[[..>>..>>>....>>>>>.<<<<<<<<<.<<<<......>
>>>>>>>>>>.>>....>>>>>>>>>>>>>..<<.<...<<<<<<.....
<<<<<<<<<..<<<....<<<<<<<....>>>>>>>.....>>>...<<<
..<<.<<........>>>>.>>>....>>>>>>>>>...<<.......>>
......>>>>>>......>.>>..<<<<<<....<.<<<....>>>.><<
<<<<<<<<...<<<.<<<<<<<<<...<<<....<<<..<.<<<..<<<<
.<.<.....>.>.>>>>>>>.>..>>>..>.>>...>>>>>>>...<<<<
<<<<<.<......>>>>>>>>>>....>>>>>>>>>>>>.>>>..<<<<.
<<<<<.....>>>>>.>>>>....<<<......>>>...<<<<<<<...<
<<(((.......<<<<<.....<<..........<<<.<<<<<<<<<<..
.....<<<<<.<<.....................>>.........<<...
...>>...>>>>>...>>>>>>>>>>>>>..........))).>>...>>
>>>..>>>...>>>>>>><<<<<<.<<<....................]]
.}..............>>>>>>>>>....>>>>>>.<.<<<<<<<<.<<.
.....<<<<.<<<<....>>>>>>>>...>>>>>>>>>>..>.....>>>
>>><<<....<<.....<<<<<<.......>>>>>>.<<<.....<<<<<
.<<...<<<<<<...<<.....>>.>>>>>>....((<<<<<<...<<..
..<<<....>>>..........<<.<<<<<<<<<...>>>>>>>>>>>..
....>>....>>...<<<<<........>>>>>))<<<<....<<<<...
<<<<<<<<....>>>>>>>>..<<<....>>>...<..<<<<<<<...<<
<<<<<<<<<<<<<<<<<<<<<..{{{..>>>>>>.....<<<<.<<<<.<
<<<.....<<<.....>>>.....>>>>>>>>..>>>>......<<<<<<
<.......>>>>>>>>>>>.>.>>>>>>>>>>>>.........>>>>>>>
..>..........>..>>>.>>>>>>>>..>>.....<<......>>>>>
>>.<<<<.....>>>>..>>>....<<<<.....<<<<<<<.<<......
.........<<<<<....<<..>>.....>>>>><<.<<<<<<<<<<<..
.<<<<<..>>>>>........>>>>>..>>>>>>.>>............<
<<<<<<<<..<<<.........>>>..<<<<<<<....<<<<.....>>>
>......>>>>>>>...<<..<<<..<<<<<<....<<<.....<<<<..
..>>>>.....>>>.>>>>..>>>>><<<<<<.......>>>>>>.....
...<...........<<<<<.......>>>>>.....>.....>>....>
>.>>>>>>>.....>>.>>>>>>>..>>>>>>...>>>....<<<<<...
.....>>>>>....[[[[[..{{{.{{......[[[[.{{[[[[..<<<<
<.<<<<<<<<<.<<<<<<<<<<<<.<<<<..........<<<<<..<<<.
.>>>............>>>>>.>>>>.>>.>>>>>>>>>>...<<<<<..
...<<<<..<<.<.<<<<....>>>>.>>>..............<<<<<<
<<<<<.....>>>>>>>>>>>..>>>>..>>>>>....>>>>>>>>>..>
>>>>...<<<.....>>>..<<<<<<...........>>>>>>..<<...
<<<<<<<...<<<<<<.......>>>>>>.....<<...(((>>....>>
>>>>>...<<<..<<<<.......>>>>..>>>.<<<....>>>.>>)))
.......((((((..(((..>>>>>>.)))))))))..........]]]]
..}}]]]].......<<.<...<<<<<<...<<.......>>...>>>>>
>....>.>.>.........<<<.<<<<<<..<.<.<<<<<......>>>>
>...>.>.<<<.<.....>.>>>.....>>>>>..>...>>>.......<
<<<<<<....>>>.>>>>....}}..}}}.]]]]].....<<<<<<.<..
<<<..<.<<<<<.................>>>>>.><<<<....<<<<..
..<<.<<<<<<<}}}.>>>>>..>>.>>...>>>>...>>>><<<<<...
<<<<<...........>>>>>...>>>>>.>>>...>.>>>>>>......
<<<<<<...<<<<....<<<........<<<<<..<<<<..>>>>.>>>>
>.......>>>...<<<..<<<<....<<<<<<<<<........>>>>>>
.>>>...>>>>..>>>..............>>>>....>>>>>>.<<<<<
.<.............>....<<.<<<<<<<.<<.....<<<<....<<<<
<......>>>>>...>>>>....>>....>>>>.>>>.>>..>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7toq Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
K38 T45 R47 R48 K50 T51 L52 R53 R55 R56 Q57 P58 K59 Y60 R62 T83 S85 K88 N93 N105 K106 H107 K123 N125 T126 L127 I128 P130 K134 K135 Y137 R139
Binding residue
(residue number reindexed from 1)
K1 T8 R10 R11 K13 T14 L15 R16 R18 R19 Q20 P21 K22 Y23 R25 T46 S48 K51 N56 N68 K69 H70 K86 N88 T89 L90 I91 P93 K97 K98 Y100 R102
Gene Ontology
--> -->
 
 
UnboundLocalError
Python 3.6.8: /usr/bin/python3
Fri Nov 15 16:38:00 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()
   1435     title=pdb2title(pdbid)
   1436     if bs.startswith("BS"):
=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)
   1438     else:
   1439         if lig3:
pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '7toq', asym_id = 'AL25', bs = 'BS01', title = 'Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.'
 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='7toq', asym_id='AL25', bs='BS01', title='Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.')
   1295         display_ec(ec,csaOrig,csaRenu)
   1296     if go:
=> 1297         display_go(go,uniprot,pdbid,asym_id)
   1298     return pubmed,uniprot
   1299 
global display_go = <function display_go>, go = '0003735,0005840,0006412,0019843', uniprot = '', pdbid = '7toq', asym_id = 'AL25'
 /var/www/html/BioLiP/pdb.cgi in display_go(go='0003735,0005840,0006412,0019843', uniprot='', pdbid='7toq', asym_id='AL25')
    480         '''.replace("$namespace_link",namespace_link
    481           ).replace("$namespace",namespace
=>  482           ).replace("$uniprot",u
    483         ))
    484         for l,(term,name) in enumerate(go2aspect[Aspect]):
u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>