Structure of PDB 7tor Chain AL24 Binding Site BS01

Receptor Information
>7tor Chain AL24 (length=63) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKVELCSFSGYKIYPGHGRRYARTDGKVFQFLNAKCESAFLSKRNPRQIN
WTVLYRRKHKKGQ
Ligand information
>7tor Chain A28S (length=3552) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgcgaccucagaucagacguggcgacccgcugaauuuaagcauauuaguc
agcggaggaaaagaaacuaaccaggauucccucaguaacggcgagugaac
agggaagagcccagcgccgaauccccgccccgcggcggggcgcgggaaau
guggcguacggaagacccacuccccggcgcgggggcccaaguccuucuga
ucgaggcccagcccguggacggugugaggccgguagcggcccccggcgcg
ccgggcccgggucuucccggagucggguugcuugggaaugcagcccaaag
cgggugguaaacuccaucuaaggcuaaauaccggcacgagaccgauaguc
aacaaguaccguaagggaaaguugaaaagaacuuugaagagagaguucaa
gagggcgugaaaccguuaagagguaaacgggugggguccgcgcaguccgc
ccggaggauucaacccggcggcgcgguccggccgugccggcggggcggau
ccccgcucucggcgggggaccgccccccggccggcgaccggccgccgccg
ggcgcauuuccaccgcggcggugcgccgcgaccggcuccgggacggcugg
gaaggccccggcggggaagguggcccgggggccccggguguuacagcccc
gccccggcagcagcagcucgccgaaucccggggccgagggagcgagaccc
gugcgccgcgcucuccccccggggggccgggccaccccucccacggcgcg
accgcuggggcggacuguccagugcgccccgggcgggucgcgccgucggg
cccggggggccacgcguccagcgcacggggucggcggcgaugucggcuac
ccacccgacccgucuugaaacacggaccaaggagucuaacacgugcgcga
gucgggggcuacgaaagccgccguggcgcaaugaaggugaaggccggccg
gccgaggugggaucccgaggcaguccgccgagggcgcaccaccggcccgu
cucgcccgccgcgccggggagguggagcacgagcgcacguguuaggaccc
gaaagauggugaacuaugccugggcagggcgaagccagaggaaacucugg
uggagguccguagcgguccugacgugcgaaucggucguccgaccugggua
uaggggcgaaagacuaaucgaaccaucuaguagcugguucccuccaaagu
uucccucaggauagcuggcgcucuccgcaguuuuauccgguaaagcgaau
gauuagaggucuuggggccgaaacgaucucaaccuauucucaaacuuuaa
auggguaagaagcccggcucgcugguguggagccgggcguggaaugcgag
ugccuagugggccacuuuugguaagcagaacuggcgcugcgggaugaacc
gaacgccggguuaaggcgcccgaugccgacgcucaucagaccccagaaaa
gguguugguugauauagacagcaggaugguggccauggaagucggaaucc
gcuaaggaguguguaacaacucaccugccgaaucaacuagcccugaaaau
ggauggcgcuggagcgucgggcccauacccggccgucgcuggcagucggc
agagcgagaaagagagggacgcuacgccgcgacgaguaggagggccgcug
cggugagccuugaagccuagggcgcgggcccggguggagccgccgcaggu
gcagaucuuggugguaguagcaaauauucaaacgagaacuuugaaggccg
aaguggagaaggguuccaugugaacagcaguugaacaugggucagucggu
ccugagagaugggcgagcgccguuccgaagggacgggcgauggccuccgu
ugcccucagccgaucgaaagggagucggguucagauccccgaauccggag
uggcggagaugggcgccgcgaggcguccagugcgguaacgcgaccgaucc
cggagaagccggcgggagccccggggagaguucucuuuucuuugugaagg
gcagggcgcccuggaauggguucgccccgagagaggggcccgugccuugg
aaagcgucgcgguuccggcggcguccggugagcucucgcuggcccuugaa
aauccgggggagaggguguaaaucucgcgccgggccguacccauauccgc
agcaggucuccaaggugaacagccucuggcauguuggaacaauguaggua
agggaagucggcaagccggauccguaacuucgggauaaggauuggcucua
agggcucagccgacuuagaacuggugcggaccaggggaauccgacuguuu
aauuaaaacaaagcaucgcgaaggcccgcggcggguguugacgcgaugug
auuucugcccagugcucugaaugucaaagugaagaaauucaaugaagcgc
ggguaaacggcgggaguaacuaugacucucuuaagguagccaaaugccuc
gucaucuaauuagugacgcgcaugaauggaugaacgagauucccacuguc
ccuaccuacuauccagcgaaaccacagccaagggaacgggcuuggcggaa
ucagcggggaaagaagacccuguugagcuugacucuagucuggcacggug
aagagacaugagagguguagaauaagugggaggccggccgccggugaaau
accacuacucugaucguuuuuucacugacccggugaggcgggggggcgag
ggcucucgcuucuggcgccaagcgcccggcgccgggcgcgacccgcuccg
gggacagugccagguggggaguuugacuggggcgguacaccugucaaacg
guaacgcagguguccuaaggcgagcucagggaggacagaaaccucccgug
gagcagaagggcaaaagcucgcuugaucuugauuuucaguacgaauacag
accgugaaagcggggccucacgauccuucugaccuuuuggguuuuaagca
ggaggugucagaaaaguuaccacagggauaacuggcuuguggcggccaag
cguucauagcgacgucgcuuuuugauccuucgaugucggcucuuccuauc
auugugaagcagaauucaccaagcguuggauuguucacccacuaauaggg
aacgugagcuggguuuagaccgucgugagacagguuaguuuuacccuacu
gaugauguguuguugccaugguaauccugcucaguacgagaggaaccgca
gguucagacauuugguguaugugcuuggcugaggagccaauggggcgaag
cuaccaucugugggauuaugacugaacgccucuaagucagaaucccgccc
aggcggaacgauagccggagccucgguuggccucggauagccgguccccc
ggggguccggugcggagagcccuucgucccgggaaacggggcggccggaa
agggggccgcccucucgcccgucacgcaccgcacguucguggggaaccug
gcgcuaaaccauucguagacgaccugcuucugggucgggguuucguacgu
agcagagcaggcugcgaucuauugaaagucagcccucgacacaaggguuu
gu
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.>>>>>>>...<<<<<<<<<.<......>>>>>>>>>>....>>>>>>>>
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>...<<<<<<<...<<<(((.......<<<<<.....<<..........<
<<.<<<<<<<<<<.......<<<<<.<<<...................>>
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....<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<<
<<...<<....<<<....>>>..........<<.<<<<<<<<<...>>>>
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..<<<<<..<<<<<<<<....>>>>>>>>..<<<....>>>...<..<<<
<<<<...<<<<<<<<<<<<.<<<<<<<<<<..[[[..>>>>>>....<<<
<<.<<<<.<<<<.....<<<.....>>>.....>>>>>>>>..>>>>>..
...<<<<<<<.......>>>>>>>>>>>...>>>>>>>>>>>>.......
..>>>>>>>..>..........>>.>>>.>>>>.>>>..>>.....<<..
....>>>>>>>.<<<<.....>>>>..>>>....<<<<.....<<<<<<<
.<<...............<<<<<....<<..>>.....>>>>><<.<<<<
<<<<<<.>>>>..>>>>>>.>>............<<<<<<<<<..<<<..
.......>>>..<<<<<<<....<<<<.....>>>>......>>>>>>>.
..<<..<<<..<<<<<<....<<<.....<<<<....>>>>.....>>>.
>>>>..>>>>><<<<<<.......>>>>>>........<...........
<<<<<.......>>>>>.....>.....>>....>>.>>>>>>>.....>
>.>>>>>>>..>>>>>>....>>....<<<<<........>>>>>....<
<<<<..<<<.<<......<<<<.<<<<<<..<<<<<.<<<<<<<<<.<<<
<<<<<<<<<.<<<<...........<<<<..<<<..>>>...........
.>>>>..>>>>.>>.>>>>>>>>>>...<<<<<.....<<<<..<<.<<.
...>>>>..............<<<<<<<<..>>>>>>>>..>>>>..>>>
>>....>>>>>>>>>..>>>>>...<<<.....>>>..<<<<<<......
.....>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>...
..<<...(((>>....>>>>>>>...<<<..<<<<.......>>>>..>>
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>>...<<<<<.<.............>....<<.<<<<<<<.<<.....<<
<<....<<<<.>>>>...>>>>....>>....>>>>.>>>.>>..>>>>>
..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7tor Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
G16 H17 G18 A34 K35 R44 I49 N50 W51 R56 K61
Binding residue
(residue number reindexed from 1)
G16 H17 G18 A34 K35 R44 I49 N50 W51 R56 K61
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7tor, PDBe:7tor, PDBj:7tor
PDBsum7tor
PubMed35589706
UniProtG1SE28|RL24_RABIT Large ribosomal subunit protein eL24 (Gene Name=RPL24)

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