Structure of PDB 6olz Chain AL Binding Site BS01

Receptor Information
>6olz Chain AL (length=205) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APSRNGMVLKPHFHKDWQRRVATWFNQPARKIRRRKARQAKARRIAPRPA
SGPIRPIVRCPTVRYHTKVRAGRGFSLEELRVAGIHKKVARTIGISVDPR
RRNKSTESLQANVQRLKEYRSKLILFPRKPSAPKKGDSSAEELKLATQLT
GPVMPVRNVYKKEKARVITEEEKNFKAFASLRMARANARLFGIRAKRAKE
AAEQD
Ligand information
>6olz Chain A3 (length=157) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
cgaacgcacuugcggccccggguuccucccggggcuacgccugucugagc
gucgcuu
.........................................<<<<<<<<<
....>>>>.....<.<<<......>>.............>>>..>...>>
>....<<....>><<<<<<<<.......>>>>>>>>..............
.......
Receptor-Ligand Complex Structure
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PDB6olz Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		N27 A30 R34
Binding residue
(residue number reindexed from 1)		N26 A29 R33
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0001824 blastocyst development
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0060348 bone development
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005840 ribosome
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0045202 synapse
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6olz, PDBe:6olz, PDBj:6olz
PDBsum6olz
PubMed31160784
UniProtP26373|RL13_HUMAN Large ribosomal subunit protein eL13 (Gene Name=RPL13)

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