Structure of PDB 7qi5 Chain AK Binding Site BS01

Receptor Information
>7qi5 Chain AK (length=101) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HYVDWRMWRDVKRRKMAYEYADERLRINSLRKNTILPKILQDVADEEIAA
LPRDSCPVRIRNRCVMTSRPRGVKRRWRLSRIVFRHLADHGQLSGIQRAT
W
Ligand information
>7qi5 Chain AA (length=954) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auagguuugguccuagccuuucuauuagcucuuaguaagauuacacaugc
aagcauccccguuccagugaguucacccucuaaaucaccacgaucaaaag
ggacaagcaucaagcacgcagcaaugcagcucaaaacgcuuagccuagcc
acacccccacgggaaacagcagugauuaaccuuuagcaauaaacgaaagu
uuaacuaagcuauacuaaccccaggguuggucaauuucgugccagccacc
gcggucacacgauuaacccaagucaauagaagccggcguaaagaguguuu
uagaucacccccuccccaauaaagcuaaaacucaccugaguuguaaaaaa
cuccaguugacacaaaauagacuacgaaaguggcuuuaacauaucugaac
acacaauagcuaagacccaaacugggauuagauaccccacuaugcuuagc
ccuaaaccucaacaguuaaaucaacaaaacugcucgccagaacacuacga
gccacagcuuaaaacucaaaggaccuggcggugcuucauaucccucuaga
ggagccuguucuguaaucgauaaaccccgaucaaccucaccaccucuugc
ucagccuauauaccgccaucuucagcaaacccugaugaaggcuacaaagu
aagcgcaaguacccacguaaagacguuaggucaagguguagcccaugagg
uggcaagaaaugggcuacauuuucuaccccagaaaacuacgauagcccuu
augaaacuuaagggucgaagguggauuuagcaguaaacugagaguagagu
gcuuaguugaacagggcccugaagcgcguacacaccgcccgucacccucc
ucaaguauacuucaaaggacauuuaacuaaaaccccuacgcauuuauaua
gaggagacaagucguaacaugguaaguguacuggaaagugcacuuggacg
aacc
..((((..<<<<<<.)))).<<<<<<.<<..<<<<<<<<....<<<.<<<
..<......>......<<.......<<<<.<..<<<.....>>>.>..>>
>>..<<<<....<<...<<<....>>>..>>......>>>>.<<...>>.
>>.<<<....>>>.....>>>>>>.........<<<....<<<<....>>
>>..>>>..>>.>>>>>>.....<<<<<<<<.....(((.....((.>>>
)).......)))..>>>>>..>>.>>>>>>....<<<((.....<<<<..
<<<<...............<<<<<<......<<<.<<<.<<<......>>
>..>>>.>>>.............<<....>>.>>>>>>.....>>>>...
>>>>....<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>
..........<.<<<<<......))..>>>>>.>.>>>.<<.......<<
<<....>>>>.....>>..>>>>>><<<<<.<<<<<<<...<<<.<<<<<
..<<<<<<<<<<.....<<........>>..........<<<<<<<....
...<<.<<<..<<<<<<.......<<..<<<<<.....>>>.......>>
..>>.....<<<....>>>.........>>>...>>>>>>>>....>>>>
>>>..>>.>>>>>>>>.....<<<<.....>>>>.....<....<<<<<<
<.......>>>>>>>....>.....>>>>>.....<<<<<<<........
.>>>>>>>.....>>>...>>>>>>>>>>.>>....<..<<.<...<<<<
<<..<<<<<......<<<...<<<.....>>>..>>>.......>>>>>.
>>>>>>....>.>>...>.....<<<<<<<<<....>>>>>>>>>.....
....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7qi5 Structure of mitoribosome reveals mechanism of mRNA binding, tRNA interactions with L1 stalk, roles of cofactors and rRNA modifications.
Resolution2.63 Å
Binding residue
(original residue number in PDB)		H28 Y29 D31 W32 R33 W35 R36 R40 R51 N55 R58 I75 R80 C83 V85 R86 R88 N89 R90 T94 R96 P97 R98 G99 K101 R102 R108 I109 R112 T127 W128
Binding residue
(residue number reindexed from 1)		H1 Y2 D4 W5 R6 W8 R9 R13 R24 N28 R31 I48 R53 C56 V58 R59 R61 N62 R63 T67 R69 P70 R71 G72 K74 R75 R81 I82 R85 T100 W101
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:0031965 nuclear membrane
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7qi5, PDBe:7qi5, PDBj:7qi5
PDBsum7qi5
PubMed38769321
UniProtO60783|RT14_HUMAN Small ribosomal subunit protein uS14m (Gene Name=MRPS14)

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