Structure of PDB 6p5j Chain AK Binding Site BS01

Receptor Information
>6p5j Chain AK (length=212) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SRDTLYEAVREVLHGNQRKRRKFLETVELQISLKNYDPQKDKRFSGTVRL
KSTPRPKFSVCVLGDQQHCDEAKAVDIPHMDIEALKKLNKNKKLVKKLAK
KYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENMVAKVDEVKSTI
KFQMKKVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVRALY
IKSTMGKPQRLY
Ligand information
>6p5j Chain 1 (length=205) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caucauucuaugguuacccaucauuagaggaaauuuccaauaaacucugg
uguaaggcuuagagugauggucgaggugcccuauuuagggugaggagccu
cgguggcagccccaccaaauccucuauuggauaggaacagcuguacuggg
caguuacagcagucguaugguaacacaugcggcguuccgaaauaccaugc
cuggc
..<<<<<<<<.<.....<...<<<<<<<<......(((.[....>>>>>>
>>...>..>>>>>>>>>.......(((<<<<<....>>>>><<<<.))).
.<<<<<.....>>>>>....>>>>..].)))..<<<<..<<<<<<..(((
((..>>>>>>.<<<<<<<<......>>>>>>>>.>>>>.........)))
))...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6p5j The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		S50 G51 K95 K98 L99 K118 P121 R122 I123 P126 L128 N129 K130 F134 P135 K161
Binding residue
(residue number reindexed from 1)		S45 G46 K90 K93 L94 K113 P116 R117 I118 P121 L123 N124 K125 F129 P130 K156
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000470 maturation of LSU-rRNA
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6p5j, PDBe:6p5j, PDBj:6p5j
PDBsum6p5j
PubMed31609474
UniProtG1SKZ8|RL10A_RABIT Large ribosomal subunit protein uL1 (Gene Name=RPL10A)

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