Structure of PDB 4v7h Chain AK Binding Site BS01

Receptor Information

>4v7h Chain AK (length=125) Species: 5541 (Thermomyces lanuginosus)

DNSQVFGVARIYASFNDTFVHVTDLSGKETIARVTGGMKVKADRDESSPY
AAMLAAQDVAAKCKEVGITAVHVKIRATGGTRTKTPGPGGQAALRALARS
GLRIGRIEDVTPVPSDSTRKKGGRR

Ligand information

>4v7h Chain AA (length=1761)

uaucugguugauccugccaguagucauaugcuugucucaaaguuaagcca
ugcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcucau
uaaaucaguuauguuuauuugauagacauggauaaccgugguauucuaga
gcuaauacaugcuuaaaaucucgacccuuuggaagagauguauuuauuag
auaaaaaaucaaugucuucggacucuuugaugauucauaauaacuuuucg
aaucgcauggccuugugcuggcgaugguucauucaaauuucugcccuauc
aacuugaugguaggauaguggccuaccaugguuucaacggguacggggaa
uaaggguucgauuccggagagggagccugagaaacggcuaccacauccaa
ggaaggcagcaggcgcgcaaauuacccaauccuaauucagggagguagug
acaauaaauaacgauacagggcccauucgggucuuguaauuggaaugagu
acaauguaaauaccuuaacgaggaacaauuggaggcaagucuggugccag
cagccgcgguaauuccagcuccaauagcguauauuaaaguuguugcaguu
aaaaagcucguaguugacuuugggcccgguuggccgguccgauuuuuucg
uguacuggauuuccaacggggccuuuccuucuggcuaaccuugaguccuu
guggcucuuggcgaaccaggacuuuacuuugaaaaaauuagaguguucaa
agcaggcguauugcucgaauauauuagcauggaauaauagaauaggacuu
ugguucuauuuuguugguuucuaggaccaucguaaugauuagggacgguc
gggggcaucgguauucaauugucgaggugaaauucuuggauuuauugaag
acuaacuacugcgaaagcauuugccaaggacguuuucauuaaucaagaac
gaaaguuaggggaucgaagaugaucugguaccgucguagucuuaaccaua
aacuaugccgacuagaucgggugguguuuuuuuaaugaccacucgguacc
uuacgagaaaucaaagucgguucuggggggaguauggucgcaaggcugaa
acuuaaaggaauugacggaagggcacccuaggaguggagccugcggcuaa
uuugacucaacacggggaaacucaccagguccagacacaauaaggauuga
cagauugagagcucuuucuugauuuugugggugguggugcauggccguuu
cuaguugguggagugauuugucugcuuaauugcgauaacgaacgagaccu
uaaccuacuaaauaguggugcuagcauuugcugguuauccacuucuuaga
gggacuaucgguuucaagccgauggaaguuugaggcaauaacaggucugu
augcccuuaacguucugggccgcacgcgcgcuacacugacggagccagcg
agucuaaccuuggccgagaggucuugguaaucuugugaaacuccgucgug
cuggggauagagcauuguaauuauugcucuucaacgaggaauuccuagua
agcgcaagucaucagcuugcguugauuacgucccugcccuuuguacacac
cgcccgucgcuaguaccgauugaauggcuuagugaggccucaggaucugc
uuagagaagggggcaacuccaucucagagcggagaauuuggacaaacuug
gucauuuagaggaacuaaaagucguaacaagguuuccguaggugaaccug
cggaaggauca

...<<<<<.[.((((>>>>><<<<..<<<<<.....<.........<<<.
<<<..<<...<<..........<<.......>>..>>>>......<<...
.....<<<..<<.<<....<<<.....<<<.....<..<<......>>..
>......>>>........<<<<..<<....>>..>>>>.......<<<<.
........<<<..<<<....>>>....>>>.......>>>>.........
.......<.<........>>........>>>...>>>>..>>>.<<<...
.<<<..<<<<<<<<.......>>>>>>>>>>>......>>>..<<<<<<<
<....>>>>...>>>>.>>.<<.<<.<.........>>>.>>...<<...
.>>.....>>>>>>.........<<<....<<<.....>>>..>>>....
...>.......<<<<<<....<<<....>>>....>>>.>>>........
..<<..........>>.............<<<<(((....<<<<.....<
..))).>.......>>>>.>>>>...>>>>>.>>>>.........<<<((
.....<.<<...<<<.......<<<<<..<...<<<<<<<<<.....>>>
.>.>>>>>.......>..>>>>>..<<<......<<.......<<<<<<.
<<.<<.....>>..>>.>>>>>>..<<<<<<<.....>>>>>>><<<...
.<<<<.....>>>.>..>>>.....>>...<<<<<<<<<<<<<<<<<<..
..>>>>>>>>>>>>>>.>>>>..>>>...............<<<<<<.<<
...<<<<......<<<<<<.<..<<<......>>>......>.>>>>>.>
..........<<....>>...>>>>...>>>>.>>>>...>>>...>>.>
....<<<<<<<.......<<<<.<.....>.>>>>....>>>>>>>....
......<<<<<.....<<<<<<<<..<<........>>>>>>>>>>....
....<<..))>>....>>>>>.>>>.<<<......<<<......>>>...
.>>>..)))).]<<<<<.<<<<<<<.....<<<<<..<<<.<<<<<<...
..<<........>>..........<<<<<.<.....<<<<.<<.......
.<<<........>>>.......>>>>>>....<..<<<..<<<<<<<<..
...<<<.<<<<......>>...<<<......>>>...>>.>>>....<<<
<<.<<<...<<..<<<<<.<<<<<<....>>>>>>...>>>>>..>>..>
>>....<<<<<<.....>>>>>>.......>>>>>.....>>.>>>...>
>>>>>.>....>.>>>>>...>>.>>>>.>>>.....<<<<<<<.....<
<<....<<<................>>>...>>>......>>>>>>>...
...<..<.<<<<..............>>>>>...>.....>>>>>.....
<<<<<<<<.......>>>>>>>>...........>>>>>>>>>>.>>...
....<<.<..<<<..<<..<.<<<<<<<<.<<<....<<..<...<<<<<
<<.<<<<.<<<<....>>>>.>>>>.>>>>>>>...>..>>....>>>.>
>>>>>>>>..>>..>>>...>.>>..........<<<<<<<<....>>>>
>>>>.......

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4v7h Comprehensive molecular structure of the eukaryotic ribosome.
• Resolution: 8.9 Å
• Binding residue (original residue number in PDB): R18 Y20 S22 N24 D25 F27 H29 G35 E37 R41 T43 G44 G45 K49 D51 R52 R84 R127 K128 K129 G130 G131 R132 R133
• Binding residue (residue number reindexed from 1): R10 Y12 S14 N16 D17 F19 H21 G27 E29 R33 T35 G36 G37 K41 D43 R44 R76 R119 K120 K121 G122 G123 R124 R125

Gene Ontology

--> -->

UnboundLocalError

Python 3.6.8: /usr/bin/python3 Sat Nov 23 04:41:46 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1435     title=pdb2title(pdbid)

   1436     if bs.startswith("BS"):

=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)

   1438     else:

   1439         if lig3:

pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '4v7h', asym_id = 'AK', bs = 'BS01', title = 'Comprehensive molecular structure of the eukaryotic ribosome.'

 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='4v7h', asym_id='AK', bs='BS01', title='Comprehensive molecular structure of the eukaryotic ribosome.')

   1295         display_ec(ec,csaOrig,csaRenu)

   1296     if go:

=> 1297         display_go(go,uniprot,pdbid,asym_id)

   1298     return pubmed,uniprot

   1299 

global display_go = <function display_go>, go = '0003735,0005840,0006412', uniprot = '', pdbid = '4v7h', asym_id = 'AK'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0003735,0005840,0006412', uniprot='', pdbid='4v7h', asym_id='AK')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>