Structure of PDB 4v4w Chain AK Binding Site BS01

Receptor Information
>4v4w Chain AK (length=116) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RKQVSDGVAHIHASFNNTIVTITDRQGNALGWATAGGSGFRGSRKSTPFA
AQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNAAGFRITNITD
VTPIPHNGCRPPKKRR
Ligand information
>4v4w Chain AA (length=1488) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugaagaguuugaucauggcucagauugaacgcuggcggcaggccuaacac
augcaagucgaacgguccggaagaagcuuucuuuuggacaguggcggacg
ggugaguaaugucugggaaacugccugauggagggggauaacuacuggaa
acgguagcuaauaccgcauaacgucgcaagaccaaagagguuuucuugcc
aucggaugugcccagaugggauuagcuaguaggugggguaacggcucacc
uaggcgacgaucccuagcuggucugagaggaugaccagccacacuggaac
ugagacacgguccagacuccuacgggaggcagcaguggggaauauugcac
aaugggcgcaagccugaugcagccaugccgcguguaugaagaaggccuuc
ggguuguaaaguacuuucgcggggaggaagggagcgacgagcucauugac
guuacccgcgaaguagcaccggcuaacuccgugccagcagccgcgguaau
acggagggugcaagcguuaaucggaauuacugggcguaaagcgcacgcag
gcgguuuguuaagucagaugugaaauccccgggcucaaccugggaacugc
aucugauacuggcaagcuugagucucguagagggggguagaauuccaggu
guagcggugaaaugcguagagaucuggaggaauaccgguggcgaaggcgg
cccccuggacgaagacugacgcucaggugcgaaagcguggggagcaaaca
ggauuagauacccugguaguccacgccguaaacgaugucgacuuggaggu
ugugucucguggcuuccggagcuaacgcguuaagucgaccgccuggggag
uacggccgcaagguuaaaacucaaaugaauugacgggggcccgcacaagc
gguggagcaugugguuuaauucgaugcaacgcgaagaaccuuaccugguc
uugacauccacggaaguuuucagagaugagaaugugccuucgggaaccgu
gagacaggugcugcauggcugucgucagcucguguugugaaauguugggu
uaagucccgcaacgagcgcaacccuuauccuuuguugccagcgguccggc
cgggaacucaaaggagacugccagugauaacuggaggaagguggggauga
cgucaagucaucauggcccuuacgaccagggcuacacacgugcuacaaug
gcgacuacaaagagaagcgaccucgcgagagcaagcggaccucauaaagu
gcgucguaguccggauuggagucugcaacucgacuccaugaagucggaau
cgcuaguaaucguggaucagaaugccacggugaauacguucccgggccuu
guacacaccgcccgucacaccaugggaguggguugcaaaagaaguaggua
gcaaccuucggggcgcuuaccacuuugugauucaugacuggggugaaguc
guaacaagguaaccguaggggaaccugcgguuggauca
....<<<<....((((.>>>>.<<<<..<......<<<<<<<.....<<<
.<<<..<<<..<<.<<<<<<<<<<.....>>>>>>>>>>.>>>>>.....
.<<.......<<<<<<<..<<...<<<<<<<.<.<<.....<<<<<....
..>>>>>......>>.>.....<<<....>>>....<<<<...>>>>.>>
>>>>>..>>.>>>>>>><<<....<<<..<<<<<<<.........>>>>>
>>>>>......>>>..<<<<<<<<....>>>...>>>>>.>>.<<<<<.<
.........>>>>>>.<<<<....>>>>...>>>>>>.........<<<.
..<<<<<....>>>>.>>>>..>>.>>>>>...<<<<......<<<<<..
>>>>>.....>>>>..<<<<<<<.......<<<<<.....>>>>.>....
....>>>>>>>....<<<<<(((...<<<<<.....<<.)))>>......
.>>>>>>>>>>......>>>>>..........<<<((.....<<<<...<
<<.<<<<<<<.<<<<<<<<<<......<<<<<<.....>>>>>>....>>
>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<<....<<<<<<<<
.<.<<<......>>>.....>>>>>>>>>...........<<....>>.>
>>>>>>..>>>>.>>>>...>>>...>>>>....<<<<<<...<<...<<
<<.<.....>.>>>>...>>>>>>>>..........<<<<<<.<<<<<<<
<<<<...>>>>>>>>>>>..<<..))>>.....>>>>>>.>>>..<<...
...<<<<....>>>>....>>...))))..<<<<<.<<<<<<<.....<<
<<<..<<<<<<<<<<......<<........>>..........<<<<<<<
......<<.......<<<<<<<....>>>>>>>...<......>......
..>>.<<<.<<<..<<<<<<.......<<<<<<<<<....>>>..<<<<.
.....>>>>..>>>>>>.....<<<..<<<<<<<...<...<<<.....>
>>.>....>>>>>>>.....<<<<<....>>>>>.........>>>....
.....>>>...>>>>>>>>>...>>>>>>>...>>.>>>>>>>>......
<<<........<<<..<....<<<....>>>....>....>>>.......
.>>>............<<<<<<<........>>>>>>>..........>>
>>>.....<<<<<<<.........>>>>>>>...........>>>>>>>>
>>.>>.......<<.<.<<<<.<<<..<<<<<<<<<<<<....<<<<<<.
....<<....>>..>>>>>>...>>>>>>>>>>>>..>>>.>>>>..>.>
>.........<<<<<<<<<....>>>>>>>>>......
Receptor-Ligand Complex Structure
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PDB4v4w Elongation arrest by SecM via a cascade of ribosomal RNA rearrangements
Resolution15.0 Å
Binding residue
(original residue number in PDB)		I30 W43 G47 G48 R52 G53 S54 I115 P116 H117 N118 G119 C120 K124 R127
Binding residue
(residue number reindexed from 1)		I19 W32 G36 G37 R41 G42 S43 I104 P105 H106 N107 G108 C109 K113 R116
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0070181 small ribosomal subunit rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4v4w, PDBe:4v4w, PDBj:4v4w
PDBsum4v4w
PubMed16713583
UniProtP0A7R9|RS11_ECOLI Small ribosomal subunit protein uS11 (Gene Name=rpsK)

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