Structure of PDB 6nu3 Chain AJ Binding Site BS01

Receptor Information
>6nu3 Chain AJ (length=108) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATLNQMHRLGPPKRPPRKLGPTEGRPQLKGVVLCTFTRKPKKPNSANRKC
CRVRLSTGREAVCFIPGEGHTLQEHQIVLVEGGRTQDLPGVKLTVVRGKY
DCGHVQKK
Ligand information
>6nu3 Chain AA (length=923) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auagguuugguccuagccuuucuauuagcucuuaguaagauuacacaugc
aagcauccccguuccagugaguucacccucuaaaucgaucaaaaggaaca
agcaucaagcacgcagcaaugcagcucaaaacgcuuagccuagccacacc
cccacgggaaacagcagugauuaaccuuuagcaauaaacgaaaguuuaac
uaagcuauacuaaccccaggguuggucaauuucgugccagccaccgcggu
cacacgauuaacccaagucaauagaccggcguaaagaguguuuuagauca
caauaaagcuaaaacucaccugaguuguaaaaaacuccaguugacacaaa
auagacuacgaaaguggcuuuaacauaucugaacacacaauagcuaagac
ccaaacugggauuagauaccccacuaugcuuagcccuaaaccucaacagu
ucaacaaaacugcucgccagaacacuacgagccacagcuuaaaacucaaa
ggaccuggcggugcuucauaucccucuagaggagccuguucuguaaucga
uaaaccccgaucaaccucaccaccucuugcucagccuauauaccgccauc
uucagcaaacccugaugaaggcuacaaaguaagcgcaaguacccacguaa
agacguuaggucaagguguagcccaugagguggcaagaaaugggcuacau
uuucuaccccagaaacgauagcccuuaugaaauaagggucgaagguggau
uuagcaguaaacuaagaguagagugcuuaguugaacagggcccugaagcg
cguacacaccgcccgucacccuccucaaguauacuucaaaggacuuaacu
aaaaccccuacgcauuuauauagaggagacgucguaacaugguaagugua
cuggaaagugcacuuggacgaac
..((((..<<<<<<.)))).<<<<<<.<...<<<<<<<<..<.<<<.<<<
..<......>......<<........<<<....<<..>>....>>>...<
<<<....<<<..<<<....>>>.>>>......>>>>.<<...>>.>>.<<
<....>>>.....>>>>>>>........<<<....<<<<....>>>>..>
>>..>>.>>>>>>.....<<<<<<<<.....(((.....((.>>>))...
....)))..>>>>>...>.>>>>>>..<<<((......<<<..<<<<...
...<<<<<<........<...<.<<........>>..>...>........
.......<<....>>.>>>>>>.....>>>>...>>>....<<<<<<<..
.<<...<<<<.........>>>>...>>>>>>>>..>.......<.<<<<
<..))..>>>>>.>.>>>.<<.......<<<<....>>>>.....>>..>
>>>>><<<<<.<<<<<<<...<<<.<<<<<..<<<<<<<.<<.....<<.
.......>>..........<<<<<<<.......<<.<<<..<<<<<<...
....<<..<<<<<.....>>>.......>>..>>.....<<<....>>>.
........>>>...>>>>>>>>....>>>>>>>..>>..>>>>>>>....
...<<.....>>...<....<<<<<<.......>>>>>>....>.....>
>>>>.....<<<<<<<.........>>>>>>>.....>>>...>>>>>>>
>>>.>>........<.....<<<<<<...<<<<...........<.....
..>.............>>>>..>>>>>>....>..........<<<<<<<
<<....>>>>>>>>>........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6nu3 Structural insights into unique features of the human mitochondrial ribosome recycling.
Resolution4.4 Å
Binding residue
(original residue number in PDB)		A31 N34 Q35 R38 P42 K43 R55 P56 Q57 L58 K59 P73 N74 S75 N77 R78 S86 P96 G97 E98 G99 H100 G112 Q116 D117 G128 K129 G133 H134 K137
Binding residue
(residue number reindexed from 1)		A1 N4 Q5 R8 P12 K13 R25 P26 Q27 L28 K29 P43 N44 S45 N47 R48 S56 P66 G67 E68 G69 H70 G82 Q86 D87 G98 K99 G103 H104 K107
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6nu3, PDBe:6nu3, PDBj:6nu3
PDBsum6nu3
PubMed30962385
UniProtO15235|RT12_HUMAN Small ribosomal subunit protein uS12m (Gene Name=MRPS12)

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