Structure of PDB 4v6i Chain AJ Binding Site BS01

Receptor Information
>4v6i Chain AJ (length=112) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VEEQEQQQQIIKIRITLTSTKVKQLENVSSNIVKNAEQHNLVKKGPVRLP
TKVLKISTRKTPNGEGSKTWETYEMRIHKRYIDLEAPVQIVKRITQITIE
PGVDVEVVVASN
Ligand information
>4v6i Chain CA (length=1721) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaaguuaagcca
ugcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcucau
uaaaucaguuaucguuuauuugauagacauggauaacugugguaauucua
gagcuaauacauguuaaaaucucgacccuuuggaagagauguauuuauua
gauaaaaaaucaaugucuucggacucuuugaugauucauaauaacuuuuc
gaaucgcauggccuugugcuggcgaugguucauucaaauuucugcccuau
caacuuuaugguaggauaguggccuaccaugguuucaacggguaacgggg
aauaaggguucgauuccggagagggagccugagaaacggcuaccacaucc
aaggaaggcagcaggcgcgcaaauuacccaauccuaauucagggagguag
ugacaauaaauaacgauacagggcccauucgggucuuguaauuggaauga
guacaauguaaauaccuuaacgaggaacaauuggagggcaagucuggugc
cagcagccgcgguaauuccagcuccaauagcguauauuaaaguuguugca
guuaaaaagcucguaguugaacuuugggcccgguuggccgguccgauuuu
uucguguacuggauuuccaacgggguccuucuggcuaaccuugaguccuu
guggcucuuggcgaaccaguguucaaagcaggcguauugcucgaauauac
guuugguucuauuuuguugguuucuaggaccaucguaauggggacggucg
ggggcaucaguauucaauugucagaggugaaauucuuggauuuauugaag
acuaacuacugcgaaagcauuugccaaggacguuuucauuaaucaagaac
gaaaguuaggggaucgaagaugaucagauaccgucguagucuuaaccaua
aacuaugccgacuagggaucgggugguguuuuuuuaaugacccacucggc
accuuagagaaaucaaagucuuuggguucuggggggaguauggucgcaag
gcugaaacuuaaaggaauugacggaagggcaccaccaggaguggagccug
cggcuuaauuugacucaacacggggaaacucaccagguccagacacaaua
aggauugacagauugagagcucuuucuugauuuugugggugguggugcau
ggccguucuuaguugguggagugauuugucugcuuaauugcgauaacgaa
cgagaccuuaaccuacuaaauaguggugcuagcauuugcugguuauccac
uucuuagagggacuaucgguuucaagccgauggaaguugaggcaauaaca
ggucugugaugcccuuaacguucugggcgcacgcgcgcuacacugacgga
gccagcgagucuaaccuuggccgagaggucuugguaaucuugugaaacuc
cgucgugcuggggauagagcauuguaauuauugcucuucaacgaggaauu
ccuaguaagcgcaagucaucagcuugcguugauuacgucccugcccuuug
uacacaccgcccgucgcuaguaccgauugaauggcuuagugaggccucag
gaucugcuuagagaagggggcaacuccaucucagagcggagaauuuggac
aaacuuggucauuuagaggaacuaaaagucguaacaagguuuccguaggu
gaaccugcggaaggaucauua
...<<<<<.[.((((>>>>><<<<..<<<<<...<...........<<<.
<<<...<...<<.....<............>....>>>.......<<...
.....<<<..<<..<<...........<<<<.....<<.<<<.....>>>
.>>......>>>>.<.<<<.........>>>.>....<.<<<<[......
((...((..<..<.....>..>.............>.]..>>>.>.....
<..<<<<.<<<<.....>>>>>>>>>.........>>>>..>>>.<<<..
..<<<..<<<<<<<.........>>>>>>>>>>......>>>...<<<<<
<<<....>>>>...>>>>.>>.<<.<<<..........>>>.>>.<.<<.
...>>.>...>>>>>>.......<.<<<...<<<<.....>>>.>>>>>.
.......>.....<<<<<<<<<<<<<....>>>>>>>>>>.>>>......
..............................<<<<<((......<<<<...
..<<..))>>.......>>>>.>>>>>..>>>>>.>>>>.........<<
<[[.....<.<<...<<<..............<..<.....<..<..<..
...>..>...>..>...>.......<...<.<<.<.<...<<..<....>
..>>...>.>.>>.>...>.<<.....<..<......>..>.....>>.<
...<<<<<<<<.....))...)).>>>>>>>>..>......<<<<<.<<.
..<<<<..<<<.<<<<<<.<...<<<......>>>......>.>>>>>>.
>>>......<<<....>>>..>>>>..>>.>>>.>>....>>>...>>.>
....<<<<<<<...<...<<<<.........>>>>...>>>>>>>>....
......<<<.<<.<<<..<<<<<<<<.<<<<.....>.>>>>>>>>>>>.
.>>>..<<.].]>>...>>.....>>>.>>>.<<<......<<<......
>>>....>>>..)))).]<<<<<.<<<<<<<...<..<<<<<..<<<.<<
<<<<......<..........>..........<<<<<........<<..<
<<....<<............>>........>>>..>>...<..<<<..<<
.<<<<<<....<<<.<<<<......>>...<<<......>>>...>>.>>
>......<<..<<<.<<<<..<<<<..<<<<<......>>>>>....>>>
>..>>>>>>>.....<<<<.......>>>>........>>......>>>.
>>>.....>>>>>.>......>>>>>..>>.>>>>.>>>.....<<<<<.
........<..........<<<....>>>..........>.........>
>>>>...........<<<<<<..........>>>>>>..........>>>
>>.....<<<<<<<<<.....>>>>>>>>>......>....>>>>>>>>>
>.>>.......<<.<..<<...<<....<<<<<<<<.<<<..<.<<....
..<<<<<<<.<<<<.<<<<....>>>>.>>>>.>>>>>>>......>>.>
..>>>.>>>>>>>>...>>...>>...>.>>.........<<<<<<<<<.
...>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4v6i Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.
Resolution8.8 Å
Binding residue
(original residue number in PDB)		L58 R68 T70 P71 N72 G73 E74 G75 W79 T81 Y82 K88 R89 Y90
Binding residue
(residue number reindexed from 1)		L49 R59 T61 P62 N63 G64 E65 G66 W70 T72 Y73 K79 R80 Y81
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4v6i, PDBe:4v6i, PDBj:4v6i
PDBsum4v6i
PubMed20980660
UniProtP38701|RS20_YEAST Small ribosomal subunit protein uS10 (Gene Name=RPS20)

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