Structure of PDB 4v4w Chain AJ Binding Site BS01

Receptor Information
>4v4w Chain AJ (length=96) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS
PHVNKDARDQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQI
Ligand information
>4v4w Chain AA (length=1488) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugaagaguuugaucauggcucagauugaacgcuggcggcaggccuaacac
augcaagucgaacgguccggaagaagcuuucuuuuggacaguggcggacg
ggugaguaaugucugggaaacugccugauggagggggauaacuacuggaa
acgguagcuaauaccgcauaacgucgcaagaccaaagagguuuucuugcc
aucggaugugcccagaugggauuagcuaguaggugggguaacggcucacc
uaggcgacgaucccuagcuggucugagaggaugaccagccacacuggaac
ugagacacgguccagacuccuacgggaggcagcaguggggaauauugcac
aaugggcgcaagccugaugcagccaugccgcguguaugaagaaggccuuc
ggguuguaaaguacuuucgcggggaggaagggagcgacgagcucauugac
guuacccgcgaaguagcaccggcuaacuccgugccagcagccgcgguaau
acggagggugcaagcguuaaucggaauuacugggcguaaagcgcacgcag
gcgguuuguuaagucagaugugaaauccccgggcucaaccugggaacugc
aucugauacuggcaagcuugagucucguagagggggguagaauuccaggu
guagcggugaaaugcguagagaucuggaggaauaccgguggcgaaggcgg
cccccuggacgaagacugacgcucaggugcgaaagcguggggagcaaaca
ggauuagauacccugguaguccacgccguaaacgaugucgacuuggaggu
ugugucucguggcuuccggagcuaacgcguuaagucgaccgccuggggag
uacggccgcaagguuaaaacucaaaugaauugacgggggcccgcacaagc
gguggagcaugugguuuaauucgaugcaacgcgaagaaccuuaccugguc
uugacauccacggaaguuuucagagaugagaaugugccuucgggaaccgu
gagacaggugcugcauggcugucgucagcucguguugugaaauguugggu
uaagucccgcaacgagcgcaacccuuauccuuuguugccagcgguccggc
cgggaacucaaaggagacugccagugauaacuggaggaagguggggauga
cgucaagucaucauggcccuuacgaccagggcuacacacgugcuacaaug
gcgacuacaaagagaagcgaccucgcgagagcaagcggaccucauaaagu
gcgucguaguccggauuggagucugcaacucgacuccaugaagucggaau
cgcuaguaaucguggaucagaaugccacggugaauacguucccgggccuu
guacacaccgcccgucacaccaugggaguggguugcaaaagaaguaggua
gcaaccuucggggcgcuuaccacuuugugauucaugacuggggugaaguc
guaacaagguaaccguaggggaaccugcgguuggauca
....<<<<....((((.>>>>.<<<<..<......<<<<<<<.....<<<
.<<<..<<<..<<.<<<<<<<<<<.....>>>>>>>>>>.>>>>>.....
.<<.......<<<<<<<..<<...<<<<<<<.<.<<.....<<<<<....
..>>>>>......>>.>.....<<<....>>>....<<<<...>>>>.>>
>>>>>..>>.>>>>>>><<<....<<<..<<<<<<<.........>>>>>
>>>>>......>>>..<<<<<<<<....>>>...>>>>>.>>.<<<<<.<
.........>>>>>>.<<<<....>>>>...>>>>>>.........<<<.
..<<<<<....>>>>.>>>>..>>.>>>>>...<<<<......<<<<<..
>>>>>.....>>>>..<<<<<<<.......<<<<<.....>>>>.>....
....>>>>>>>....<<<<<(((...<<<<<.....<<.)))>>......
.>>>>>>>>>>......>>>>>..........<<<((.....<<<<...<
<<.<<<<<<<.<<<<<<<<<<......<<<<<<.....>>>>>>....>>
>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<<....<<<<<<<<
.<.<<<......>>>.....>>>>>>>>>...........<<....>>.>
>>>>>>..>>>>.>>>>...>>>...>>>>....<<<<<<...<<...<<
<<.<.....>.>>>>...>>>>>>>>..........<<<<<<.<<<<<<<
<<<<...>>>>>>>>>>>..<<..))>>.....>>>>>>.>>>..<<...
...<<<<....>>>>....>>...))))..<<<<<.<<<<<<<.....<<
<<<..<<<<<<<<<<......<<........>>..........<<<<<<<
......<<.......<<<<<<<....>>>>>>>...<......>......
..>>.<<<.<<<..<<<<<<.......<<<<<<<<<....>>>..<<<<.
.....>>>>..>>>>>>.....<<<..<<<<<<<...<...<<<.....>
>>.>....>>>>>>>.....<<<<<....>>>>>.........>>>....
.....>>>...>>>>>>>>>...>>>>>>>...>>.>>>>>>>>......
<<<........<<<..<....<<<....>>>....>....>>>.......
.>>>............<<<<<<<........>>>>>>>..........>>
>>>.....<<<<<<<.........>>>>>>>...........>>>>>>>>
>>.>>.......<<.<.<<<<.<<<..<<<<<<<<<<<<....<<<<<<.
....<<....>>..>>>>>>...>>>>>>>>>>>>..>>>.>>>>..>.>
>.........<<<<<<<<<....>>>>>>>>>......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4v4w Elongation arrest by SecM via a cascade of ribosomal RNA rearrangements
Resolution15.0 Å
Binding residue
(original residue number in PDB)		R9 R45 R48 K59 D60 R62
Binding residue
(residue number reindexed from 1)		R5 R41 R44 K55 D56 R58
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0001072 transcription antitermination factor activity, RNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0031564 transcription antitermination
GO:0032784 regulation of DNA-templated transcription elongation
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0008023 transcription elongation factor complex
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4v4w, PDBe:4v4w, PDBj:4v4w
PDBsum4v4w
PubMed16713583
UniProtP0A7R5|RS10_ECOLI Small ribosomal subunit protein uS10 (Gene Name=rpsJ)

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