Structure of PDB 6yxx Chain AI Binding Site BS01

Receptor Information
>6yxx Chain AI (length=240) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VAPWVPPPRHDIKVTMPPPPGGEVGGRFGVSQGYSDRLARTPYWKRMALS
TYKLRMMENATRYPMSEHRPGEYDIRYLPTPYPCTIRNRPLLEVGEPRQI
PSIRIPVIFLVNLFDEAKGCWFGRRYETVYVERQFMREELMPQRYAIYAT
PEAYKLLGLPVVNHHTHEEIPKTPREYEKLLERQRYDEERWKYTIEYLFR
KYEDGPPELLDRPEDGWDGSEEIALSSVAGAAAAAAAAAA
Ligand information
>6yxx Chain AA (length=904) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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uaguguauaguuuuuuaaaaauauaaaaauauuguuaaaacaaauaaaau
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gggcaaguccuacucuccuuuacaaagagaacauuaugauauguaauugu
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.........................................>>.>.....
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...........<<....>>.............<<<....<<<<<<.....
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.................>>>>>>.......>>>.................
.......<<<<<<<<..........>>>>>>>>.................
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......>>>>................................>>>><...
.................<<<<<<.................>>>>>>....
.....................<<<.....<<<<<<<..>>>>>.>>..>>
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.................>>>...>>>.>>>.......<<<<<.......>
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..>>..........>........>>>>>>>>>..................
<<..<..................>>>........................
....
Receptor-Ligand Complex Structure
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PDB6yxx Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		Y90 P91 T93 E104 P105 R106 I108
Binding residue
(residue number reindexed from 1)		Y82 P83 T85 E96 P97 R98 I100
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:0031981 nuclear lumen
GO:0097014 ciliary plasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6yxx, PDBe:6yxx, PDBj:6yxx
PDBsum6yxx
PubMed32679035
UniProtQ57UC5

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