Structure of PDB 6vlz Chain AI Binding Site BS01

Receptor Information
>6vlz Chain AI (length=136) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KFSIYPPIPGEESSLRWAGKKFEEIPIAHIKASHNNTQIQVVSASNEPLA
FASCGTEGFRNAKKGTGIAAQTAGIAAAARAKQKGVIHIRVVVKGLGPGR
LSAMHGLIMGGLEVISITDNTPIPHNGCRPRKARKL
Ligand information
>6vlz Chain AA (length=944) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auagguuugguccuagccuuucuauuagcucuuaguaagauuacacaugc
aagcauccccguuccagugaguucacccucuaaaucaccacgaucaaaag
gaacaagcaucaagcacgcagcaaugcagcucaaaacgcuuagccuagcc
acacccccacgggaaacagcagugauuaaccuuuagcaauaaacgaaagu
uuaacuaagcuauacuaaccccaggguuggucaauuucgugccagccacc
gcggucacacgauuaacccaagucaauagaagccggcguaaagaguguuu
uagaucacccccaauaaagcuaaaacucaccugaguuguaaaaaacucca
guugacacaaaauagacuacgaaaguggcuuuaacauaucugaacacaca
auagcuaagacccaaacugggauuagauaccccacuaugcuuagcccuaa
accucaacaguuaaaucaacaaaacugcucgccagaacacuacgagccac
agcuuaaaacucaaaggaccuggcggugcuucauaucccucuagaggagc
cuguucuguaaucgauaaaccccgaucaaccucaccaccucuugcucagc
cuauauaccgccaucuucagcaaacccugaugaaggcuacaaaguaagcg
caaguacccacguaaagacguuaggucaagguguagcccaugagguggca
agaaaugggcuacauuuucuaccccagaaacgauagcccuuaugaaacuu
aagggucgaagguggauuuagcaguaaacuaagaguagagugcuuaguug
aacagggcccugaagcgcguacacaccgcccgucacccuccucaaguaua
cuucaaaggacauuuaacuaaaaccccuacgcauuuauauagaggagaca
agucguaacaugguaaguguacuggaaagugcacuuggacgaac
..((((..<<<<<<.)))).<<<<<<.....<<<<<<<<..<.<<<.<<<
..<......>......<<........<<<....<<<.....>>>....>>
>...<<<<....<<<..<<<....>>>.>>>......>>>>.<<...>>.
>>.<<<....>>>.....>>>>>>>........<<<....<<<<....>>
>>..>>>..>>.>>>>>>.....<<<<<<<<.....(((.....((.>>>
)).......)))..>>>>>.....>>>>>>....<<<((.....<<<<..
<<<<..........<<<<<<......<<<.<<<.<<<......>>>..>>
>.>>>............<<<....>>>>>>>>>.....>>>>...>>>>.
..<<<<<<<...<<...<<<<.........>>>>...>>>>>>>>..>..
.....<.<<<<<......))..>>>>>.>.>>>.<<.......<<<<...
.>>>>.....>>..>>>>>><<<<<.<<<<<<<...<<<.<<<<...<<<
<<<<<<<.....<<........>>..........<<<<<<<.......<<
.<<<..<<<<<<.......<<..<<<<<.....>>>.......>>..>>.
....<<<....>>>.........>>>...>>>>>>>>....>>>>>>>..
>>.>>>>>>>>.....<<<<.....>>>>.......<<<<<.........
>>>>>............>>>>.....<<<<<<<.........>>>>>>>.
....>>>...>>>>>>>>>>.>>.......<<.<...<<<<<<..<<<<<
..<..........<.......>..........>..>>>>>.>>>>>>...
.>.>>.........<<<<<<<<<....>>>>>>>>>........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6vlz Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation.
Resolution2.97 Å
Binding residue
(original residue number in PDB)		H87 N93 N94 Q96 Q98 N104 P106 F109 S111 N119 A120 K122 P180 I181 P182 H183 N184 G185 C186 R187 K190 R192 K193
Binding residue
(residue number reindexed from 1)		H29 N35 N36 Q38 Q40 N46 P48 F51 S53 N61 A62 K64 P122 I123 P124 H125 N126 G127 C128 R129 K132 R134 K135
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6vlz, PDBe:6vlz, PDBj:6vlz
PDBsum6vlz
PubMed32737313
UniProtP82912|RT11_HUMAN Small ribosomal subunit protein uS11m (Gene Name=MRPS11)

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