Structure of PDB 6p5i Chain AI Binding Site BS01

Receptor Information
>6p5i Chain AI (length=205) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGH
MVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINK
MLQTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNKEHVVEALRRAKFKF
PGRQKIHISKKWGFTKFNADEFEDMVAEKRLIPDGCGVKYIPNRGPLDKW
RALHS
Ligand information
>6p5i Chain 1 (length=205) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caucauucuaugguuacccaucauuagaggaaauuuccaauaaacucugg
uguaaggcuuagagugauggucgaggugcccuauuuagggugaggagccu
cgguggcagccccaccaaauccucuauuggauaggaacagcuguacuggg
caguuacagcagucguaugguaacacaugcggcguuccgaaauaccaugc
cuggc
..<<<<<<<<...........<<<<<<<<......(((......>>>>>>
>>.......>>>>>>>>.......(.(<<<<<....>>>>><<<<<).).
.<<<<<.....>>>>>...>>>>>....)))..<<<<<.<<<<<<..(((
((..>>>>>>.<<<<<<<<......>>>>>>>>>>>>>.........)))
))...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6p5i The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		I33 L36 I70 K74
Binding residue
(residue number reindexed from 1)		I32 L35 I69 K73
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0006412 translation
GO:0006417 regulation of translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6p5i, PDBe:6p5i, PDBj:6p5i
PDBsum6p5i
PubMed31609474
UniProtB7NZQ2|RL10_RABIT Large ribosomal subunit protein uL16 (Gene Name=RPL10)

[Back to BioLiP]