Structure of PDB 6hiv Chain AI Binding Site BS01

Receptor Information
>6hiv Chain AI (length=212) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VAPWVPPPRHDIKVTMPPPPGGEVGGRFGVSQGYSDRLARTPYWKRMALS
TYKLRMMENATRYPMSEHRPGEYDIRYLPTPYPCTIRNRPLLEVGEPRQI
PSIRIPVIFLVNLFDEAKGCWFGRRYETVYVERQFMREELMPQRYAIYAT
PEAYKLLGLPVVNHHTHEEIPKTPREYEKLLERQRYDEERWKYTIEYLFR
KYEDGPPELLDR
Ligand information
>6hiv Chain AA (length=591) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auuuuaccaauuaagaagaauauuauaauaaugggugucuuauauuuuaa
auaaauauuuaaauuccguguaguaaauuuauuauuuguauuauuuauau
aauagguguauuauauuuaaauuuuaaauuuguuguuuuauauuuagaua
cauauuuauagauuaauauauuuaaauaauauuuuaaaauuuauugaaaa
auaaauauaguaagauuauuuuaguaaauauuuauuuuucuuuguaaaua
uuauuaacuaaaauguuauauauaauaaucuaaguuaauuugaauauuaa
aaguacaaguauaauuuguaauucuaaaguauauuuauauuuuuaguagg
uaaaugaaaaguauaaauggauauaacuuaauauuuaauauuuguuuaau
gaaaaguauuuuauuauuauauuguauaguauuauuauaguguauaguuu
uuuaaaaauauaaaaaauaaaguaugaauuaauaucaaaauuuuaauaaa
aauuaaaaaauuaaaauaagaaacauuaugauauguacuauauucuuugu
auuuaauuuuuauaauuaauaagaaagaagaauauaauuua
....<<<................<<.........................
............<.....>......................>>.......
.......>>>..............<<<<........>>>><<<<......
...........<<....>>.............<<<....<<<<<<....>
>>>>>.......>>>...........<<<<<<<<..........>>>>>>
>>....<<<<............<...............<<<.......>>
>...........<<<.....>>>.......>............>>>>...
.............................>>>><.......<........
..................................................
..........<....>.......>......>.......<<<<<......>
>>>>....<<<<<<.<<<....<<<<......>>>>..<<.......>>>
>>>>>>>>.................................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6hiv Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Resolution7.8 Å
Binding residue
(original residue number in PDB)		R35 Y90 P105 R106 Q142
Binding residue
(residue number reindexed from 1)		R27 Y82 P97 R98 Q134
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:0031981 nuclear lumen
GO:0097014 ciliary plasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6hiv, PDBe:6hiv, PDBj:6hiv
PDBsum6hiv
PubMed30213880
UniProtQ57UC5

[Back to BioLiP]