BioLiP

Receptor Information

>6gaw Chain AI (length=328) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TVDFIKKQIEEFNIGKRHLANMMGEDPETFTQEDIDRAIAYLFPSGLFEK
RARPIMKHPEEIFPKQRAIQWGEDGRPFHFLFYTGKQSYYSLMHDTYGKL
LDVEKHHNQLRAKDLLAEKTKILKDPIGSRWLIKEELEEMLVEKLSDQDY
AQFIRLLERLSALPCGATEEDFVNRFRRSIPIQSKKQLIEPLQYDEQGMA
FSRGEGKRKTAKAEVVVYGQGSGRIDVNGVDYLLYFPVTQDREQLMFPLH
FLDRLGKHDMTCAVSGGGRSAQAGAVRLAMARALCSFVTEDEVEWMRQAG
LLTADPRVRERKKPGQEGARRKFTWKKR

>6gaw Chain AA (length=960) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

acagguuugguccuggccuuucuauuaauucuuaauaaaauuacacaugc
aaguauccgcgccccggugagaaugcccuccagaucuuaaagaucaaaag
gagcagguaucaagcacaccuauaacgguagcucauaacgccuugcucaa
ccacacccccacgggaaacagcagugauaaaaauuaagccaugaacgaaa
guuugacuaaguuauauuaauuagaguugguaaaucucgugccagccacc
gcggucauacgauuaacccaaauuaauagauccacggcguaaagaguguu
uaagaaaaaaaaucacaauagaguuaaauuauaacuaagcuguaaaaagc
ccuaguuaaaauaaaauaacccacgaaagugacucuaauaauccugacac
acgauagcuaggacccaaacugggauuagauaccccacuaugccuagccc
uaaacccaaauaguuacauaacaaaacuauucgccagaguacuacucgca
acugccuaaaacucaaaggacuuggcggugcuucacauccaccuagagga
gccuguucuauaaucgauaaaccccgauagaccuuaccaacccuugccaa
uucagccuauauaccgccaucuucagcaaacccuaaaaaggaacaauagu
aagcacaaucauagcacauaaaaacguuaggucaagguguagcuuauggg
uuggaaagaaaugggcuacauuuucuacauaagaauauccaccacacgaa
aguuuuuaugaaacuaaaaaccaaaggaggauuuagcaguaaaucaagaa
uagagugcuugauugaauaaggccaugaagcacgcacacaccgcccguca
cccuccucaagcauguaguaauaaaaauaaccuauauucaauuacacaac
caugcaagaagagacaagucguaacaagguaagcauacuggaaagugugc
uuggauuacc

..((((..<<<<<<.)))).<<<<<<<<<..<<<<<<<<....<<<.<<<
..<<....>>......<<......<<<<<...<<<<<...>>>>>...>>
>.>>.<<<....<<...<<<......>>>..>>......>>>..<.....
>.>>.<<<....>>>.....>>>>>>..........<<....<<<<....
>>>>..>>...>>.>>>>>>...<.<<<<<<.....(((.....((.>>>
)).......)))..>>>.>..>>>>>>>>>.....<<<((.....<<<<.
..<<..............<<<<<<....<..<<<<<<.<<<......>>>
..>>>>>>..>...........<<....>>.>>>>>>......>>...>>
>>....<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>..
........<<<<<<<.....))..>>>>>>>.>>>.<<<........<<.
...>>......>>>..>>>>>><<<<<.<<<<<<<...<<..<<<<<..<
<<<<<<<<<.....<<........>>..........<<<<<<<.......
...<<<.<<<..<<<<<<.......<<..<<<<<....>>>.......>>
..>>......<<.....>>..........>>>...>>>>>>>>>...>>>
>>>>..>>.>>>>>>>>.....<<<<.....>>>>...........<...
.<<<<<<<......>>>>>>>....>.....>>>>>.....<<<<<<<..
.......>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<.
..<<<.<<..<<<<<..<<<<<...<<<<.....>>>>..>>>>>.....
>>>>>..>>.>>>....>.>>...>.....<<<<<<<<<....>>>>>>>
>>........

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6gaw Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM.
Resolution	3.2 Å
Binding residue (original residue number in PDB)	F117 E118 Q217 R277 K278 T279 G337 S339 A340 R376 V377 R378 E379 R380 K381 K382 P383 G387 R389 R390 K391 T393 W394 K395 K396 R397
Binding residue (residue number reindexed from 1)	F48 E49 Q148 R208 K209 T210 G268 S270 A271 R307 V308 R309 E310 R311 K312 K313 P314 G318 R320 R321 K322 T324 W325 K326 K327 R328

Enzyme Commision number

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005730	nucleolus
GO:0005739	mitochondrion
GO:0005763	mitochondrial small ribosomal subunit
GO:0005840	ribosome
GO:1990904	ribonucleoprotein complex

PDB	RCSB:6gaw, PDBe:6gaw, PDBj:6gaw
PDBsum	6gaw
PubMed	30089917
UniProt	I3LU08

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Structure of PDB 6gaw Chain AI Binding Site BS01