Structure of PDB 9cai Chain AG Binding Site BS01

Receptor Information

>9cai Chain AG (length=228) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MRLNFAYPATGLQKSFEVDEEKKLRLFFEKRMSQEVAIDALGDEWKGYVV
RIGGGNDKQGFPMKQGILTNGRVRLLLKKGQSCYRERKNGERKRKSVRGC
IVDANMSALSLVIVKKGDGEIEGLTDSVLPRKLGPKRASKIRKLFNLTKH
DDVTKYVITHDKTFPDGVTKTIAPKIQRLITPARIARKKYLLRQKRNQKI
KMRDDAAAYHKLLAKYSKEEHDAKIARR

Ligand information

>9cai Chain B2 (length=1476) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

uaccugauugauucugucagcgcgauaugcucaaguaaaagauuaagcca
ugcaugcgauucauugaaauugcguacggcucauuagagcagauaucacc
uuauccgggauggauaacugcggaaauacuggagcuaauacaugcacccc
agcggggugcaauuauuaguguugacucugaauaaagcaguuuacuguca
gcugacucuauccggaaagggugucugcccuuucaacuagaugguaguuu
auuggacuaccaugguuguuacggguaacggagaauaaggguucgacucc
ggagagggagccuuagaaacggcuaccacguccaaggaaggcagcaggcg
cgaaacuuauccacuguuguaugagauagugacuaaaaauauaguugaau
acaaaugauucuucgaggagagggcaagucuggugccagcagccgcggua
auuccagcucuccuaguguaucucguuauugcugcgguuaaaaagcucgu
aguuggaucuagguuuaccuugaauaaaucagagugcucaauacaagcgc
uugcuugaauagcaucauggaauaaugaaauuaaugguuaagagggacaa
accgggggcauucguaucauuacgcgagaggugaaauucguggaccguag
ugagacgcccaacagcgaaagcauuugccaagaaugucuucauuaaucaa
gaacgaaagucagagguucgaaggcgauuagauaccgcccuaguucugac
cguaaacgaugccaucucgcgauucggagggugcccugccgaggagcauc
cggaaacgaaagucuuucgguuccggggguaguaugguugcaaagcugaa
acuuaaagaaauugacggaagggcaccacaaggcguggagcuugcggcuu
aauuugacucaacacgggaaaacucacccgguccggacaccaugacugac
agauugaaagcucuuucucgauuuggugguugguggugcauggccguucu
uaguugguggagugauuugucugguuuauuccgauaacgagcgagacucu
agccucuaaauaguuggcgaaucuucggguucguuaacuucuuagaggga
uaagcgguguuuagccgcacgagauugagcgauaacaggucugugaugcc
cuuagauguccggggcugcacgcgugcuacacugguggagucagcggguc
cuaugccgaaagguaucgguaaaccguugaaauucuuccauguccgggau
aggguauuguaauuauugcccuuaaacgaggaaugccuaguaagugugag
ucaucagcucacguugauuacgucccugcccuuuguacacaccgcccguc
gcuauccgggacugaacugauucgagaagaguggggacugugcggaaacc
auuuuuaucgcauugguuugaaccggguaaaagucguaacaagguagcug
uaggugaaccugcagcuggaucaucg

...<<<<<.[.((((>>>>><<.<<<<<<<.....<<..<......<<<.
<<<..<<<<<<......>>>>>>......<<.......<<<<<<<<..<<
<..<<<<<..<<.....<<.<<<.....>>>.>>......>>...<<<<<
...>>>>><<..<<<<<...<......>..>>>>>....>>.....<<<<
..>>>>.....>>>>>.>>>>>>>>>>><<<....<<<..<<<<<<<<..
.....>>>>>>>>>>>......>>>...<<<.<<<<....>>>>....>>
>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>>>>.
........<<<....<.....>..>>>..>...>>........<..<<<<
.......>>>>..>..<<<<<((....<.<<<<.....<<..))>>....
...>>>>>>>>>>..>>>>>>>.>>.........<<<((.....<.<<..
.<<<.<<.......<<<<<.<<<.......<..<<.......>>.<<<..
..>>>....>....>>>.>>..>>>............>>....<<<<<<.
..<...<<<<..<<..<<<<<<<<...<<<......>>>......>>>>>
>>>..>>.......<<....>>...>>>>..>..>>>.>>>...>>>...
>>.>....<<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>>>
..........<<<..<..<<..<<<<<<<<<..>>>>.>>>>>..>>...
<<..))>>...>......>>>.>>>.<<<......<<<<....>>>>...
.>>>..)))).]<<<<<.<<<<<<<..<<.<<<<<<..<<<.<<<<<<..
....<<........>>..........<<<<<.<....<<<<<.....<<.
<<<........>>>.>>......>>>>>...<<.<<<..<<.<<<<<<..
..<<<.<<<<......>>...<<<......>>>...>>.>>>....<<<.
..<<<<<<<..<<<<<<<<<<<<....>>>>>>>>>>>>..>>>>>>>..
...<<<<<.....>>>>>........>>>....>>>.>>>.....>>>>>
>>.....>.>>>>>...>>.>>>>.>>>.....<<.<<<<......<<.<
<.<<<<<....>>>>>.>>....>>.......>>>>.>>......<....
<<<<<<..........>>>>>>....>.....>>>>>>....<<<<<<<<
.......>>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<
..<<<<<<<....<<<<<<<<.<<<.<<<<<<<<...<<<..>>>...>>
>>>>>>.>>>.>>>>>>>>...>>>>>>>...>.>>...>.....<<<<<
<<<<<..>>>>>>>>>>.........

Receptor-Ligand Complex Structure

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Structure summary

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PDB	9cai High-Resolution Reconstruction of a C. elegans Ribosome Sheds Light on Evolutionary Dynamics and Tissue Specificity.
Resolution	2.59 Å
Binding residue (original residue number in PDB)	R2 N4 Q13 S15 R31 K58 Q59 G60 F61 Q65 I67 R72 L75 S82 C83 Y84 R85 R87 K88 G90 E91 R92 K93 R94 S96 S107 A108 S110 R131 K132 L133 G134 P135 K136 R137 K140 H160 P174 K175 Q177 R178 I180 A183 R184 A186 R187 Y190 R193 M202
Binding residue (residue number reindexed from 1)	R2 N4 Q13 S15 R31 K58 Q59 G60 F61 Q65 I67 R72 L75 S82 C83 Y84 R85 R87 K88 G90 E91 R92 K93 R94 S96 S107 A108 S110 R131 K132 L133 G134 P135 K136 R137 K140 H160 P174 K175 Q177 R178 I180 A183 R184 A186 R187 Y190 R193 M202

External links

PDB	RCSB:9cai, PDBe:9cai, PDBj:9cai
PDBsum	9cai
PubMed	39209556
UniProt	Q9NEN6\|RS6_CAEEL Small ribosomal subunit protein eS6 (Gene Name=rps-6)

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