Structure of PDB 4v4b Chain AG Binding Site BS01

Receptor Information
>4v4b Chain AG (length=150) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RYANKRFRKAQCPIIERLTNSLMMNGRNNGKKLKAVRIIKHTLDIINVLT
DQNPIQVVVDAITNTGPREDTTRVGGGGAARRQAVDVSPLRRVNQAIALL
TIGAREAAFRNIKTIAETLAEELINAAKGSSTSYAIKKKDELERVAKSNR
Ligand information
>4v4b Chain AA (length=1466) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucagggugaacgcuggcggcgugccuaagac
augcaagucgugcgggccgcgccguggucagcggcggacgggugaguaac
gcgugggugaccuacccggaagagggggacaacccggggaaacucgggcu
aaucccccauguggacccgccccuugggguguguccaaagggcuuugccc
gcuuccggaugggcccgcgucccaucagcuaguuggugggguaauggccc
accaaggcgacgacggguagccggucugagaggauggccggccacagggg
cacugagacacgggccccacuccuacgggaggcagcaguuaggaaucuuc
cgcaaugggcgcaagccugacggagcgacgccgcuuggaggaagaagccc
uucgggguguaaacuccugaacgaaacccccgacgaggggacugacggua
auagcgccggccaacuccgugccagcagccgcgguaauacggagggcgcg
agcguuacccggauucacugggcguaaagggcguguaggcggccuggggc
gucccaugugaaagaccacggcucaaccgugggggagcgugggauacgcu
caggcuagacggugggagagggugguggaauucccggaguagcggugaaa
ugcgcagauaccgggaggaacgccgauggcgaaggcagccaccuggucca
cccgugacgcugaggcgcgaaagcguggggagcaaaccggauuagauacc
cggguaguccacgcccuaaacgaugcgcgcuaggucucugggucuccugg
gggccgaagcuaacgcguuaagcgcgccgccuggggaguacggccgcaag
gcugaaacucaaaggaauugacgggggcccgcacaagcgguggagcaugu
gguuuaauucgaagcaacgcgaagaaccuuaccaggccuugacaugcuag
ggaacccgggugaaagccuggggcccuagcacaggugcugcauggccguc
gucagcucgugccgugagguguuggguuaagucccgcaacgagcgcaacc
cccgccguuaguugccagcgguucggccgggcacucuaacgggacugccc
gcgaaagcgggaggaaggaggggacgacgucuggucagcauggcccuuac
ggccugggcgacacacgugcuacaaugcccacuacaaagcgaugccaccc
ggcaacggggagcuaaucgcaaaaaggugggcccaguucggauugggguc
ugcaacccgaccccaugaagccggaaucgcuaguaaucgcggaucagcca
ugccgcggugaauacguucccgggccuuguacacaccgcccgucacgcca
ugggagcgggcucuacccgaagucgccgggagccuacgggcaggcgccga
ggguagggcccgugacuggggcgaagucguaacaagguagcuguaccgga
aggugcggcuggauca
....<<<<..{...[[.>>>>.<<<<.<<<<<..<<<<<<<...<..<<<
.<<<..<<<..<<..<<<<<<.>>>>>>..>>>>>......<<.......
<<<<<<<<..<<...<<<<<<..<<<<<....<<<<<<....>>>>>>..
...>>>>>...<<<<<.<<<<<....>>>>>.>>>>>..<<<<...>>>>
..>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<<.......>>>
>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<<<
<.<.........>>>>>>.<<<<....>>>>...>>>>>>>........<
<<....<<<<....>>>>..>>>...>.>>>>>>..<<<<......<<<<
....>>>>.....>>>>..........<<<<.....>>>>..........
...<<<<<(((...<<<<<.....<<.)))>>.......>>>>>>>>>>.
.>>>>>>>>>..........<<<((.....<<<<...<<<.<<<<<<<.<
<<<<<<<<<......<<<<<<.....>>>>>>....>>>>>>>>..>>>>
>>>>>...<<<<<<<<...<<<<<<<....<<<<<<<.<..<<<......
>>>.....>.>>>>>>>...........<<....>>.>>>>>>>..>>>>
>.>>>...>>>...>>>>....<<<<<<...<<...<<<<.<.....>.>
>>>...>>>>>>>>..........<<<<<<..<<<<<<<<<<...>>>>>
>>>>>...<<..))>>.....>>>>>>.>>>.<<<......<<<<....>
>>>....>>>..]]...}<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<
<<<......<<........>>..........<<<<<<<......<<<<<<
<...<<<<<<<....>>>>>>>..>>>>>>>.<<<.<<<..<<<<<<...
....<<<<<<<<<....>>>..<<<<......>>>>..>>>>>>.....<
<<<.<<<<<<<...<...<<<.....>>>.>....>>>>>>>.....<<<
<<....>>>>>........>>>>.........>>>...>>>>>>>>>...
>>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<
<....>>>>..>>....>>>.....>>>>>>>...........<<<<<<<
........>>>>>>>..........>>>>>>....<<<<<<<........
..>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<.<<<<.
<<<..<<<<<<<<<<<<<...<.<<<<....<<<....>>>.>>>>.>..
>>>>>>>>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<...
.>>>>>>>>>......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4v4b Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation.
Resolution11.7 Å
Binding residue
(original residue number in PDB)		R75 Y76 A77 R80 M98 R101 N103 G104 K106 L107 K108 R111 N168 R184 K187 T188 I189
Binding residue
(residue number reindexed from 1)		R1 Y2 A3 R6 M24 R27 N29 G30 K32 L33 K34 R37 N94 R110 K113 T114 I115
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0015935 small ribosomal subunit

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4v4b, PDBe:4v4b, PDBj:4v4b
PDBsum4v4b
PubMed14976550
UniProtP26783|RS5_YEAST Small ribosomal subunit protein uS7 (Gene Name=RPS5)

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