Structure of PDB 4v6q Chain AF Binding Site BS01

Receptor Information
>4v6q Chain AF (length=232) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLTKELAKAS
VSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQI
NIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKV
EVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVW
IFKGEILGGMAAVEQPEKPAAQPKKQQRKGRK
Ligand information
>4v6q Chain AA (length=1542) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaauugaagaguuugaucauggcucagauugaacgcuggcggcaggccua
acacaugcaagucgaacgguaacaggaagaagcuugcuucuuugcugacg
aguggcggacgggugaguaaugucugggaaacugccugauggagggggau
aacuacuggaaacgguagcuaauaccgcauaacgucgcaagaccaaagag
ggggaccuucgggccucuugccaucggaugugcccagaugggauuagcua
guaggugggguaacggcucaccuaggcgacgaucccuagcuggucugaga
ggaugaccagccacacuggaacugagacacgguccagacuccuacgggag
gcagcaguggggaauauugcacaaugggcgcaagccugaugcagccaugc
cgcguguaugaagaaggccuucggguuguaaaguacuuucagcggggagg
aagggaguaaaguuaauaccuuugcucauugacguuacccgcagaagaag
caccggcuaacuccgugccagcagccgcgguaauacggagggugcaagcg
uuaaucggaauuacugggcguaaagcgcacgcaggcgguuuguuaaguca
gaugugaaauccccgggcucaaccugggaacugcaucugauacuggcaag
cuugagucucguagagggggguagaauuccagguguagcggugaaaugcg
uagagaucuggaggaauaccgguggcgaaggcggcccccuggacgaagac
ugacgcucaggugcgaaagcguggggagcaaacaggauuagauacccugg
uaguccacgccguaaacgaugucgacuuggagguugugcccuugaggcgu
ggcuuccggagcuaacgcguuaagucgaccgccuggggaguacggccgca
agguuaaaacucaaaugaauugacgggggcccgcacaagcgguggagcau
gugguuuaauucgaugcaacgcgaagaaccuuaccuggucuugacaucca
cggaaguuuucagagaugagaaugugccuucgggaaccgugagacaggug
cugcauggcugucgucagcucguguugugaaauguuggguuaagucccgc
aacgagcgcaacccuuauccuuuguugccagcgguccggccgggaacuca
aaggagacugccagugauaaacuggaggaagguggggaugacgucaaguc
aucauggcccuuacgaccagggcuacacacgugcuacaauggcgcauaca
aagagaagcgaccucgcgagagcaagcggaccucauaaagugcgucguag
uccggauuggagucugcaacucgacuccaugaagucggaaucgcuaguaa
ucguggaucagaaugccacggugaauacguucccgggccuuguacacacc
gcccgucacaccaugggaguggguugcaaaagaaguagguagcuuaaccu
ucgggagggcgcuuaccacuuugugauucaugacuggggugaagucguaa
caagguaaccguaggggaaccugcgguuggaucaccuccuua
........<<<<..[.((((.>>>>.<<<<..<<<<..<<<<<<<<..<.
.<<<.<<<..<<<..<<.<<..<<<<<<<<<<....>>>>>>>.>>>>>.
.>>>>>......<<........<<<<<<..<<...<<<<<<<.<.<<...
..<<<<<......>>>>>......>>.>.....<<<....>>>....<<<
<<<..<<....>>>>>>>>.>>>>>>>..>>.>>>>>>.<<<....<<..
.<<<<<<<.........>>>>>>>.>>......>>>..<<<<<<<<....
>>>>...>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>
...>>>>>>>........<<<....<<<<....>>>>..>>>..>>.>>>
>>>..<<<<......<<<<....>>>>.....>>>>...<.<<<<<....
....<<<<.<<<.......>>>.>>>>..........>>>>>....>..<
<<<<(((...<<<<<.....<..))).>.......>>>>>>>>>>..>>>
>.>>>>..........<<<((.....<<<<...<<<.<<<<<<<.<<<<<
<<<<<......<<<<<<.....>>>>>>....>>>>>>>>..>>>>>>>>
>...<<<<<<<<...<<<<<<<.....<<<<<<<...<<<......>>>.
.....>>>>>>>............<<....>>.>>>>>>>..>>>.>>>>
>...>>>...>>>>...<<<<<<<...<<...<<<<.........>>>>.
..>>>>>>>>..>.......<<<<<<..<<<<<<<<<<<<.....>>>>>
>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<......<<<<...
.>>>>....>>>..)))).]<<<<<.<<<<<<<.<<.<<<<<...<<<<<
<<<.<......<<........>>..........<<<<<<<......<<<<
<<<..<<<<<<<....>>>>>>>...<<....>>..>>>>>.>>.<<<.<
<<..<<<<<<.......<<<<<<<<<....>>>..<<<<......>>>>.
.>>>>>>.....<<<..<<<<<<....<<..<<<.....>>>>>.....>
>>>>>.....<<<<<.....>>>>>.........>>>.........>>>.
..>>>>>>>>>...>>>>>>>...>..>>>>>>>>.....<<<<<<<...
..<<<..<<...<<<....>>>...>>....>>>.....>>>>>>>....
..<....<<<<<<<........>>>>>>>....>......>>>>>....<
<<<<<<.........>>>>>>>......>>...>>>>>>>>>>.>>....
...<<.<.<<<<.<<<..<<<<<<<<<<<.....<<<<<<.<<<<..<<<
..>>>.>>>>>>>>>>....>>>>>>>>>>>..>>.>>>>>..>.>>...
......<<<<<<<<<....>>>>>>>>>..............
Receptor-Ligand Complex Structure
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PDB4v6q Structural characterization of mRNA-tRNA translocation intermediates.
Resolution11.5 Å
Binding residue
(original residue number in PDB)		G1 Q2 K3 V4 I9 I13 N24 T25 K26 E151 G154 E160 I161 A162 W166 R168 G170 R171 V172 L174 H175 T176 L177 R178 T185 E187 H189 Y192 V194 I195 K198 K218 K225 Q226 Q227 K229 R231 K232
Binding residue
(residue number reindexed from 1)		G1 Q2 K3 V4 I9 I13 N24 T25 K26 E151 G154 E160 I161 A162 W166 R168 G170 R171 V172 L174 H175 T176 L177 R178 T185 E187 H189 Y192 V194 I195 K198 K218 K225 Q226 Q227 K229 R231 K232
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4v6q, PDBe:4v6q, PDBj:4v6q
PDBsum4v6q
PubMed22467828
UniProtP0A7V3|RS3_ECOLI Small ribosomal subunit protein uS3 (Gene Name=rpsC)

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