Structure of PDB 6yxx Chain AE Binding Site BS01

Receptor Information
>6yxx Chain AE (length=344) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PSLMREKDRDMYHCYYPYLFDHGDKMSLYPKIPENPREWQPEQLQTTYDA
IREDKYDAFIRLREKFPELYQDTRAWDNPPPFGEFNMFYSVRFGMVGVKA
FTCKDYDELGNQFDCTAFWFPDNQVVKHSTRNGEVGTDKVYVGAMNVPVE
FHKPHVAAFYKAAGVPVKHVCAGFPITPDAYAPVGTKLDVRHFKPGQEVT
ITFQNTDYGFRGVMFRHGFDGGYVWLGDSRWQRRPGAMGTEGQKRIYPGH
RMAGQTGAAAETYQGVPVWRIDYKNSLIYLPTLLDADVGTYVRFSDTINT
KGLTLWNEHRGLPAFPTFIPPEDEDLSKLATDECQLKSPPLYMY
Ligand information
>6yxx Chain AA (length=904) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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Receptor-Ligand Complex Structure
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PDB6yxx Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		K172 R176 Y186 K198 H200 F204 C216 G218 F255 Q288 K289 I291 P293 G294 H295 A298 Q300 Y389
Binding residue
(residue number reindexed from 1)		K127 R131 Y141 K153 H155 F159 C171 G173 F210 Q243 K244 I246 P248 G249 H250 A253 Q255 Y344
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005739 mitochondrion
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6yxx, PDBe:6yxx, PDBj:6yxx
PDBsum6yxx
PubMed32679035
UniProtQ580R4

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