Structure of PDB 6hiv Chain AE Binding Site BS01

Receptor Information
>6hiv Chain AE (length=293) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RCYPSLMREKDRDMYHCYYPYLFDHGDKMSLYPKIPENPREWQPEQLQTT
YDAIREDKYDAFIRLREKFPELYQDTRAWDNPPPFGEFNMFYSVRFGMVG
VKAFTCKDYDELGNQFDCTAFWFPDNQVVKHSTRNGEVGTDKVYVGAMNV
PVEFHKPHVAAFYKAAGVPVKHVCAGFPITPDAYAPVGTKLDVRHFKPGQ
EVTITFQNTAAAETYQGVPVWRIDYKNSLIYLPTLLDADVGTYVRFSDTI
NTKGLTLWNEHRGLPAFPTFIPPEDEDLSKLATDECQLKSPPL
Ligand information
>6hiv Chain AA (length=591) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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....<<<................<<.........................
............<.....>......................>>.......
.......>>>..............<<<<........>>>><<<<......
...........<<....>>.............<<<....<<<<<<....>
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>>....<<<<............<...............<<<.......>>
>...........<<<.....>>>.......>............>>>>...
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>>>>....<<<<<<.<<<....<<<<......>>>>..<<.......>>>
>>>>>>>>.................................
Receptor-Ligand Complex Structure
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PDB6hiv Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Resolution7.8 Å
Binding residue
(original residue number in PDB)		R176 E179 K184 K198 H200 F204 A217 G218
Binding residue
(residue number reindexed from 1)		R134 E137 K142 K156 H158 F162 A175 G176
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005739 mitochondrion
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6hiv, PDBe:6hiv, PDBj:6hiv
PDBsum6hiv
PubMed30213880
UniProtQ580R4

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