Structure of PDB 5aj4 Chain AE Binding Site BS01

Receptor Information
>5aj4 Chain AE (length=328) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFFTKLTADELWKGALAESRRKDLNRGQIIGEGRHGFLWPGLNIPLMRNG
AVQTIAQRSKEDQEKVEADMVQQREEWDRRRKMKVKRERGWSGNTWGGVS
LGPPDPGPNGETYDDFDTRILEVRNVFNMTAKEGRKRSVRVLVAVGNGKG
AAGFAIGKATERADAFRKAKNRAVHYLHYIERYEDHTIYHDISLKFKRTH
IKMKKQPRGYGLHCHRAIMTICRLIGIKDLYAKVSGSVNMLNLTRGLFLG
LSRQETHQQLADKKSLHVVEFREECGPLPIVVASPQGALRKDPEPEDEVP
DITLDWEDVKAAQGMKRSVWSGLKRAAT
Ligand information
>5aj4 Chain AA (length=960) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acagguuugguccuggccuuucuauuaauucuuaauaaaauuacacaugc
aaguauccgcgccccggugagaaugcccuccagaucuuaaagaucaaaag
gagcagguaucaagcacaccuauaacgguagcucauaacgccuugcucaa
ccacacccccacgggaaacagcagugauaaaaauuaagccaugaacgaaa
guuugacuaaguuauauuaauuagaguugguaaaucucgugccagccacc
gcggucauacgauuaacccaaauuaauagauccacggcguaaagaguguu
uaagaaaaaaaaucacaauagaguuaaauuauaacuaagcuguaaaaagc
ccuaguuaaaauaaaauaacccacgaaagugacucuaauaauccugacac
acgauagcuaggacccaaacugggauuagauaccccacuaugccuagccc
uaaacccaaauaguuacauaacaaaacuauucgccagaguacuacucgca
acugccuaaaacucaaaggacuuggcggugcuucacauccaccuagagga
gccuguucuauaaucgauaaaccccgauagaccuuaccaacccuugccaa
uucagccuauauaccgccaucuucagcaaacccuaaaaaggaacaauagu
aagcacaaucauagcacauaaaaacguuaggucaagguguagcuuauggg
uuggaaagaaaugggcuacauuuucuacauaagaauauccaccacacgaa
aguuuuuaugaaacuaaaaaccaaaggaggauuuagcaguaaaucaagaa
uagagugcuugauugaauaaggccaugaagcacgcacacaccgcccguca
cccuccucaagcauguaguaauaaaaauaaccuauauucaauuacacaac
caugcaagaagagacaagucguaacaagguaagcauacuggaaagugugc
uuggauuacc
..((((..<<<<<<.)))).<<<<<<<<<..<<<<<<<<..<.<<<.<<<
..<<....>>......<<......<<<<<...<<<<<...>>>>>...>>
>.>>.<<<....<<...<<<......>>>..>>......>>>..<.....
>.>>.<<<....>>>.....>>>>>>>.........<<....<<<<....
>>>>..>>...>>.>>>>>>...<.<<<<<<.....(((.....((.>>>
)).......)))..>>>.>..>>>>>>>>>.....<<<((.....<<<<.
..<<..............<<<<<<.....<.<<<<<<.<<<......>>>
..>>>>>>..>...........<<....>>.>>>>>>......>>...>>
>>....<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>..
........<<<<<<<.....))..>>>>>>>.>>>.<<<........<<.
...>>......>>>..>>>>>><<<<<.<<<<<<<...<<..<<<<<..<
<<<<<<<<<.....<<........>>..........<<<<<<<.......
...<<<.<<<..<<<<<<.......<<..<<<<<....>>>.......>>
..>>......<<.....>>..........>>>...>>>>>>>>>...>>>
>>>>..>>.>>>>>>>>.....<<<<.....>>>>...........<...
.<<<<<<<......>>>>>>>....>.....>>>>>.....<<<<<<<..
.......>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<.
..<<<.<<..<<<<<<.<<<.....<<<<.....>>>>....>>>...>.
>>>>>..>>.>>>....>.>>...>.....<<<<<<<<<....>>>>>>>
>>........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5aj4 The complete structure of the 55S mammalian mitochondrial ribosome.
Resolution3.8 Å
Binding residue
(original residue number in PDB)
T91 L93 L98 K100 G101 R136 S194 G195 N196 R226 V228 F229 N230 M231 T232 A233 K234 R237 R242 I258 K260 D266 R269 K270 H277 Y278 K299 R300 H315 C316 H317 R318 Y333 A334 K335 V336 S339 V340 R347 W408 R419 S420 V421 W422 S423 L425 R427
Binding residue
(residue number reindexed from 1)
T4 L6 L11 K13 G14 R34 S92 G93 N94 R124 V126 F127 N128 M129 T130 A131 K132 R135 R140 I156 K158 D164 R167 K168 H175 Y176 K197 R198 H213 C214 H215 R216 Y231 A232 K233 V234 S237 V238 R245 W306 R317 S318 V319 W320 S321 L323 R325
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:5aj4, PDBe:5aj4, PDBj:5aj4
PDBsum5aj4
PubMed25837512
UniProtF1SU66

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