Structure of PDB 4v65 Chain AD Binding Site BS01

Receptor Information

ATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRK
VCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGA
LDCSGVKDRKQARSKYGVKRPKA

Ligand information

gcggauuuagcucaguugggagagcgccagacugaagaucuggagguccu
guguucgauccacagaauucgcacc

<<<<<<<..<<<<........>>>>.<<<<<.......>>>>>.....<<
<<<.......>>>>>>>>>>>>...

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

PDB	4v65 The Structure of the E. coli Ribosome Before and After Accommodation: Implications for Proofreading
Resolution	9.0 Å
Binding residue (original residue number in PDB)	V36 T38 T39 P41 K43 N45 A47 K50 H71 N72 Q74 E75 H76
Binding residue (residue number reindexed from 1)	V36 T38 T39 P41 K43 N45 A47 K50 H71 N72 Q74 E75 H76

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000049	tRNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0019843	rRNA binding
GO:0034336	misfolded RNA binding

	Biological Process
GO:0000372	Group I intron splicing
GO:0002181	cytoplasmic translation
GO:0006412	translation
GO:0033120	positive regulation of RNA splicing
GO:0034337	RNA folding
GO:0046677	response to antibiotic
GO:1990145	maintenance of translational fidelity

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:4v65, PDBe:4v65, PDBj:4v65
PDBsum	4v65
PubMed
UniProt	P0A7S3\|RS12_ECOLI Small ribosomal subunit protein uS12 (Gene Name=rpsL)