Structure of PDB 4v4g Chain AD Binding Site BS01

Receptor Information

>4v4g Chain AD (length=208) Species: 562 (Escherichia coli)

GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRP
SDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRL
DNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEK
SRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQ
LVIEFYSR

Ligand information

>4v4g Chain AA (length=1526)

uggagaguuugauccuggcucagggugaacgcuggcggcgugccuaagac
augcaagucgugcggauacgcgcggccccuuggggccgugcgucagcggc
ggacgggugaguaacgcgugggugaccuacccggaagagggggacaaccc
ggggaaacucgggcuaaucccccauguggacgcaaguccaaagggggaag
ccuucgggucccccgcuuccggaugggcccgcgucccaucagcuaguugg
ugggguaauggcccaccaaggcgacgacggguagccggucugagaggaug
gccggccacaggggcacugagacacgggccccacuccuacgggaggcagc
aguuaggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuu
ggaggaagaagcccuucgggguguaaacuccugaacccgggacgaaacca
gggccacucauacuggcucugacugacgguaccgggguaauagcgccggc
caacuccgugccagcagccgcgguaauacggagggcgcgagcguuacccg
gauucacugggcguaaagggcguguaggcggccuggggcgucccauguga
aagaccacggcucaaccgugggggagcgugggauacgcucaggcuagacg
gugggagagggugguggaauucccggaguagcggugaaaugcgcagauac
cgggaggaacgccgauggcgaaggcagccaccugguccacccgugacgcu
gaggcgcgaaagcguggggagcaaaccggauuagauacccggguagucca
cgcccuaaacgaugcgcgcuaggucucuggcggcucaaccgcugggggcc
gaagcuaacgcguuaagcgcgccgccuggggaguacggccgcaaggcuga
aacucaaaggaauugacgggggcccgcacaagcgguggagcaugugguuu
aauucgaagcaacgcgaagaaccuuaccaggccuugacaugcuagggaac
ccgggugaaagccuggggugccuucgggagcccuagcacaggugcugcau
ggccgucgucagcucgugccgugagguguuggguuaagucccgcaacgag
cgcaacccccgccguuaguugccagcgguucggccgggcacucuaacggg
acugcccgcgaaagcgggaggaaggaggggacgacgucuggucagcaugg
cccuuacggccugggcgacacacgugcuacaaugcccacuacaaagcgau
gccacccggcaacggggagcuaaucgcaaaaaggugggcccaguucggau
uggggucugcaacccgaccccaugaagccggaaucgcuaguaaucgcgga
ucagccaugccgcggugaauacguucccgggccuuguacacaccgcccgu
cacgccaugggagcgggcucuacccgaagucgccggguaaccuacgggaa
gaggcgccgaggguagggcccgugacuggggcgaagucguaacaagguag
cuguaccggaaggugcggcuggauca

....<<<<....(((..>>>>.<<<<.<<<<<..<<<<<<<......<<<
.<<<..<<<..<<.....<<<<..<<<<....>>>>..>>>>...>>>>>
......<<.......<<<<<<<<..<<...<<...<<....<<....<<<
..........>>>.....>>........<<<....>>>......<<<<..
........>>>.>..>>...>>..>>>>>>>>>><<<....<<<....<<
<<..........>.>>>..>>>......>>>...<<.<<<<....>>>>.
...>>..>>.<<<<<............>>>>>...<<....>>.....>>
>>>>.........<<<....<<<<....>>>>..>>>...>.>>>>>>..
<<<<......<<<......>>>.....>>>>..<<<<<<<.........<
<<<<<<.......>>>>>>>...........>>>>>.>..>.<<<<<(((
...<<<<<.....<<.)))>>.......>>>>>>>>>>..>>>>>>>>>.
.........<<.(......<<<<...<<<.<<<<<<<.<<<<.<<<<...
......<<<<.....>>>>.......>>>>.>>>..>>>>>>>>...<<<
<<<<<...<<<<<<<....<<<<<<<....<<<......>>>.......>
>>>>>>...........<<....>>.>>>>>>>..>>>>>.>>>...>>>
...>>>>....<<<<<<...<<...<<<<.........>>>>...>>>>>
>>>..........<<<<<<..<<<<<<<<<<<<.....>>>>>>>>>>>>
...<<...)>>.....>>>>>>..>>.<<<......<<<<....>>>>..
..>>>...)))..<<<<<.<<<<<<<.<<..<<<<...<<<<<<<<<<..
....<<........>>..........<<<<<<.......<<<<<.<<...
<.<<<<....>>>>.>..............>>.>>>>>.<<..<<<..<<
<<<<.......<<<<<<<<<....>>>..<<<<......>>>>..>>>>>
>.....<<<<.<<<<<.....<...<<<.....>>>>.......>>>>>.
....<<<<<....>>>>>........>>>>.........>>>...>>>>>
>.>>....>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<..
<<..<<<<....>>>>..>>....>>>.....>>>>>>>......<....
<<<<<<<........>>>>>>>....>......>>>>.....<<<<<<<.
.........>>>>>>>......>>...>>>>>>>>>>.>>.......<<.
..<<<<.<<<..<<<<<<<<<.<<....<.<<<<................
..>>>>.>...>>.>>>>>>>>>..>>>.>>>>....>>.........<<
<<<<<<<....>>>>>>>>>......

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4v4g Structural basis for the control of translation initiation during stress.
• Resolution: 11.5 Å
• Binding residue (original residue number in PDB): G2 R3 G6 P7 V8 C9 R10 K22 R25 K30 C31 A32 G41 Q42 H43 Q45 S52 Y54 Q62 R65 R66 S71 E72 R73 Q74 N77 K86 V112 S113 R115 Q116 Q119 R122 H123 H125 N129 R131 R132 V133 D134 L135 S137 Y138 R139 L155 E156 L157 E205 F206 R209
• Binding residue (residue number reindexed from 1): G1 R2 G5 P6 V7 C8 R9 K21 R24 K29 C30 A31 G40 Q41 H42 Q44 S51 Y53 Q61 R64 R65 S70 E71 R72 Q73 N76 K85 V111 S112 R114 Q115 Q118 R121 H122 H124 N128 R130 R131 V132 D133 L134 S136 Y137 R138 L154 E155 L156 E204 F205 R208

Gene Ontology

--> -->

UnboundLocalError

Python 3.6.8: /usr/bin/python3 Sat Nov 16 15:22:13 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1435     title=pdb2title(pdbid)

   1436     if bs.startswith("BS"):

=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)

   1438     else:

   1439         if lig3:

pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '4v4g', asym_id = 'AD', bs = 'BS01', title = 'Structural basis for the control of translation initiation during stress.'

 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='4v4g', asym_id='AD', bs='BS01', title='Structural basis for the control of translation initiation during stress.')

   1295         display_ec(ec,csaOrig,csaRenu)

   1296     if go:

=> 1297         display_go(go,uniprot,pdbid,asym_id)

   1298     return pubmed,uniprot

   1299 

global display_go = <function display_go>, go = '0003723,0003735,0006412,0015935,0019843', uniprot = '', pdbid = '4v4g', asym_id = 'AD'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0003723,0003735,0006412,0015935,0019843', uniprot='', pdbid='4v4g', asym_id='AD')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>