Structure of PDB 4v49 Chain AD Binding Site BS01

Receptor Information

>4v49 Chain AD (length=208) Species: 562 (Escherichia coli)

GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRP
SDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRL
DNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEK
SRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQ
LVIEFYSR

Ligand information

>4v49 Chain AA (length=1527)

uggagaguuugauccuggcucagggugaacgcuggcggcgugccuaagac
augcaagucgugcggauacgcgcggccccuuggggccgugcgucagcggc
ggacgggugaguaacgcgugggugaccuacccggaagagggggacaaccc
ggggaaacucgggcuaaucccccauguggacgcaaguccaaagggggaag
ccuucgggucccccgcuuccggaugggcccgcgucccaucagcuaguugg
ugggguaauggcccaccaaggcgacgacggguagccggucugagaggaug
gccggccacaggggcacugagacacgggccccacuccuacgggaggcagc
aguuaggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuu
ggaggaagaagcccuucgggguguaaacuccugaacccgggacgaaacca
gggccacucauacuggcucugacugacgguaccgggguaauagcgccggc
caacuccgugccagcagccgcgguaauacggagggcgcgagcguuacccg
gauucacugggcguaaagggcguguaggcggccuggggcgucccauguga
aagaccacggcucaaccgugggggagcgugggauacgcucaggcuagacg
gugggagagggugguggaauucccggaguagcggugaaaugcgcagauac
cgggaggaacgccgauggcgaaggcagccaccugguccacccgugacgcu
gaggcgcgaaagcguggggagcaaaccggauuagauacccggguagucca
cgcccuaaacgaugcgcgcuaggucucuggcggcucaaccgcugggggcc
gaagcuaacgcguuaagcgcgccgccuggggaguacggccgcaaggcuga
aacucaaaggaauugacgggggcccgcacaagcgguggagcaugugguuu
aauucgaagcaacgcgaagaaccuuaccaggccuugacaugcuagggaac
ccgggugaaagccuggggugccuucgggagcccuagcacaggugcugcau
ggccgucgucagcucgugccgugagguguuggguuaagucccgcaacgag
cgcaacccccgccguuaguugccagcgguucggccgggcacucuaacggg
acugcccgcgaaagcgggaggaaggaggggacgacgucuggucagcaugg
cccuuacggccugggcgacacacgugcuacaaugcccacuacaaagcgau
gccacccggcaacggggagcuaaucgcaaaaaggugggcccaguucggau
uggggucugcaacccgaccccaugaagccggaaucgcuaguaaucgcgga
ucagccaugccgcggugaauacguucccgggccuuguacacaccgcccgu
cacgccaugggagcgggcucuacccgaagucgccggguaaccuacgggaa
gcaggcgccgaggguagggcccgugacuggggcgaagucguaacaaggua
gcuguaccggaaggugcggcuggauca

....<<<<....[[...>>>>.<<<<.<<<<<.<<<<<<<<<..<..<<<
.<<<..<<<..<<.<<..<<<<<<<<<<....>>>>>>>>>>>>.>>>>>
......<<.......<<<<<<<<..<<...<<<<<<<.<<<<<....<<<
<<<....>>>>>>.....>>>>>...<<<<<....>>>>>..<<<<<<..
<<....>>>>>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<
<<<<.......>>>>>>>>>>>......>>>..<<<<<<<<..[.>>>>.
..>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>
>>>>>........<<<....<<<<....>>>>..>>>..>>.>>>>>>>.
<<<<......<<<<....>>>>.....>>>>....<<<<<........<<
<<<<<<.......>>>>>>>>..........>>>>>......<<<<<(((
...<<<<<.....<<.)))>>.......>>>>>>>>>>..>>>>>>>>>.
......]..<<<((.....<<<<...<<<.<<<<<<<.<<<<<<<<<<..
....<<<<<<.....>>>>>>....>>>>>>>>..>>>>>>>>>...<<<
<<<<<...<<<<<<<....<<<<<<<.<..<<<......>>>.....>.>
>>>>>>...........<<....>>.>>>>>>>..>>>>>.>>>...>>>
...>>>>....<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>
>>>..........<<<<<<..<<<<<<<<<<<<.....>>>>>>>>>>>>
...<<..))>>.....>>>>>>.>>>.<<<......<<<<....>>>>..
..>>>....]]..<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<..
....<<........>>..........<<<<<<<......<<<<<<<<..<
<<<<<<....>>>>>>>...<<....>>..>>>>>>>>.<<<.<<<..<<
<<<<.......<<<<<<<<<....>>>..<<<<......>>>>..>>>>>
>.....<<<<.<<<<<<<...<...<<<.....>>>.>....>>>>>>>.
....<<<<<....>>>>>........>>>>.........>>>...>>>>>
>>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<..
<<..<<<<....>>>>..>>....>>>.....>>>>>>>......<....
<<<<<<<........>>>>>>>....>.....>>>>>>....<<<<<<<.
.........>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.
<.<<<<.<<...<<<<<<<<<<<<<...<.<<<<......<<....>>..
...>>>>.>..>>>>>>>>>>>>>...>>.>>>>..>.>>...>.....<
<<<<<<<<....>>>>>>>>>......

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4v49 X-ray Crystal Structures of the WT and a Hyper-Accurate Ribosome From Escherichia Coli
• Resolution: 8.7 Å
• Binding residue (original residue number in PDB): G2 Y4 I5 P7 V8 C9 R10 R13 R14 K22 E24 R25 K30 R35 R36 Y38 P40 G41 Q42 H43 Q45 K46 S52 Y54 R59 Q62 E72 R73 Q74 S113 R115 Q116 Q119 H123 H125 R132 V133 D134 L135 S137 Y138 E205 S208 R209
• Binding residue (residue number reindexed from 1): G1 Y3 I4 P6 V7 C8 R9 R12 R13 K21 E23 R24 K29 R34 R35 Y37 P39 G40 Q41 H42 Q44 K45 S51 Y53 R58 Q61 E71 R72 Q73 S112 R114 Q115 Q118 H122 H124 R131 V132 D133 L134 S136 Y137 E204 S207 R208

Gene Ontology

--> -->

UnboundLocalError

Python 3.6.8: /usr/bin/python3 Tue Dec 3 01:39:36 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1435     title=pdb2title(pdbid)

   1436     if bs.startswith("BS"):

=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)

   1438     else:

   1439         if lig3:

pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '4v49', asym_id = 'AD', bs = 'BS01', title = 'X-ray Crystal Structures of the WT and a Hyper-Accurate Ribosome From Escherichia Coli'

 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='4v49', asym_id='AD', bs='BS01', title='X-ray Crystal Structures of the WT and a Hyper-Accurate Ribosome From Escherichia Coli')

   1295         display_ec(ec,csaOrig,csaRenu)

   1296     if go:

=> 1297         display_go(go,uniprot,pdbid,asym_id)

   1298     return pubmed,uniprot

   1299 

global display_go = <function display_go>, go = '0003723,0003735,0006412,0015935,0019843', uniprot = '', pdbid = '4v49', asym_id = 'AD'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0003723,0003735,0006412,0015935,0019843', uniprot='', pdbid='4v49', asym_id='AD')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>