Structure of PDB 4bts Chain AD Binding Site BS01

Receptor Information
>4bts Chain AD (length=180) Species: 5911 (Tetrahymena thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKTYINTSKTYSTPRRPYEKERLDNEMKLIGTFGLKNKREVWRVQMILAK
FRKAARELLTLDPKDPRRLFEGSALLRRMFKYGLLSEQERKLDYVLGLTI
HKLMERRLQTRVFKLNLANSIHHSRVLIRQRHIKVGKNLVNVPSFMVRTD
SEKSIDFASTSPLGGGREGRTKRKNAKKSA
Ligand information
>4bts Chain AA (length=1717) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaccugguugauccugccaguuacauaugcuugucuuaaauauuaaccca
ugcaugugccaguucaguauugaacagcgaaacugcgaauggcucauuaa
aacaguuauaguuuauuugauaauuaaagauuacauggauaaccgagcua
auuguugggcuaauacaugcuuaaaauuccguguccugcgaccggaacgu
auuuauuagauauuagaccaaucgcagcaaugugauugagaugaaucaaa
guaacugaucggaucgagguuuaccucgauaaaucaucuaaguuucugcc
cuaucagcucucgaugguaguguauuggacuaccauggcagucacgggua
acggagaauuaggguucgauuccggagaaggagccugagaaacggcuacu
acaacuacgguucggcagcagggaagaaaauuggccaauccuaauucagg
gagccagugacaagaaauagcaagcugggaaacuuacguuucuacggcau
ugaaaugagaacaguguaaaucucuuagcgaggaacaauuggagggcaag
ucauggugccagcagccgcgguaauuccagcuccaauagcguauauuaaa
guuguugcaguuaaaaagcucguaguugaacuucuguucagguucauuuc
gauucgucgugugaaacuggacauacguuugcguaaacauuuuacuguga
aaaaauuagaguguuccaggcagguuuuagcccgaauacauuagcaugga
auaauggaauaggacuaaguccauuuuauugguucuuggauuugguaaug
auuaauagggacaguugggggcauuaguauuuaauagucagaggugaaau
ucuuggauuuauuaaggacuaacuaaugcgaaagcauuugccaaagaugu
uuucauuaaucaagaacgaaaguuaggggaucaaagacgaucagauaccg
ucguagucuuaacuauaaacuauaccgacucgggaucggcuggaauaaau
guccagucggcaccguaugagaaaucaaagucuuuggguucugggggaag
uaugguacgcaagucugaaacuuaaaggaauugacggaacagcacaccag
aaguggaaccugcggcuuaauuugacucaacacggggaaacucacgagcg
caagacagagaagggauugacagauugagagcucuuucuugauucuuugg
gugguggugcauggccguucuuaguugguggagugauuugucugguuaau
uccguuaacgaacgagaccuuaaccugcuaacuagucugcuuguaaauaa
cagguuguacuucuuagagggacuauugugcaauaagccaauggaaguuu
aaggcaauaacaggucugugaugccccuagacgugcucggccgcacgcgc
guuacaaugacuggcgcaaaaaguauuuccuguccugggaagguacgggu
aaucuuauuaauaccagucguguuagggauaguucuuuggaauuguggau
cuugaacgaggaauuucuaguaagugcaagucaucagcuugcguugauua
ugucccugccguuuguacacaccgcccgucgcuuguaguaacgaaugguc
uggugaaccuucuggacugcgacagcaauguugcggaaaaauaaguaaac
ccuaccauuuggaacaacaagaagucguaacaagguaucuguaggugaac
cugcagauggaucauua
...<<<<<.{.[[[[>>>>><.<.<<<<<<...<<<<.........<<<.
<<<..<<....<<...<<........>>...>>.>>......<<..<...
..<<<..<<..<<....<<<<..............<<.....<<.<<<..
...>>>.>>......>>.........<<<<<.<<<....>>>>>>>>.<.
..<<<<<........((((((..<<<....>>>......<......>..>
>>>>.....>...<<<<<<....>>>>>>...>>>>...>>>>..>>>.<
<<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>>..
.<<<<<<<<....>>>>...>>>>>>>.<<.<<<..........>>>.>>
..<<<....>>>.....>>>>>>.........<<<....<<<.....>>>
..>>>......>>>>.....<<<<<<<.<.<<<....>>>>...>>>>.>
>>..........<<.........>>.............<<<<<((.....
...<<<.....<<..))>>.......>>>..>>>>>..>>>>>>.>.>..
.......<<<[[.....<.<<...<<<.<<....<<<<<<<.<<<<<..<
<<<..>>>>.>>>>>.>>>>>>>...<<<<<..>>>>>...<<<<<<<<.
......<<...<.......>..<<<....>>>....>>......>>>>>.
.>>>.........<<<<<<<<<<.....))))))..>>>>>>>>>>....
.>>....<<<<<<.<<...<<<<..<<..<<<<<<<<...<<<......>
>>......>>>>>>>>..>>.......<<....>>...>>>>...>>>>>
.>>>...>>>...>>.>...<<<<<<<<...<...<<<<.........>>
>>...>>>>>>>>>.........<<<.<<.<<<..<<<<<<<<<......
.>>>>>>>>>..>>>...<<..]]>>...>>.....>>>.>>>.<<<...
...<<.<<....>>>>....>>>..]]]].}<<<<<.<<<.<<<.<<.<<
<<<<..<<<.<<<<<.......<<........>>..........<<<<<<
<....<<<<<<.......<<.<<<........>>>.>>.....>>>>>>.
..<<.<<<..<<<<<<<<<....<<<.<<<<<....>>>...<<<.....
.>>>...>>.>>>....<<<<<.<<..<<<<..<<<..<<<<<<.....>
>>>>>...>>>..>>>>.>>....<<<<.<<.....>>>>>>.......>
>>>>....>>>.>>>...>.>>>>>>>.....>>>>>>>....>.>>>>.
>>>.....<<<<<<.......<<.....<<<<<<<<....>>>.>>>>>.
...>>........>>>>>>...........<<.<<<..........>>>.
>>..........>>>>>>....<<<<<<<<.......>>>>>>>>.....
.>>...>>>.>>>>>>.>>....<..<<.<.<<<<<.<<..<<<<<<<<.
.<<<..<<.<..<...<<<<<<<<....>>>>>>>>...>..>.>>..>>
>..>>>>>>>>..>>.>>>>>..>.>>...>.....<<<<<<<<<....>
>>>>>>>>.........
Receptor-Ligand Complex Structure
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PDB4bts The crystal structure of the eukaryotic 40S ribosomal subunit in complex with eIF1 and eIF1A.
Resolution3.703 Å
Binding residue
(original residue number in PDB)
G2 K3 T4 Y5 N7 T8 S9 K10 T11 T14 R16 R17 P18 Y19 K37 N38 K39 R40 R44 F71 E72 A75 R79 N120 S121 H124 R126 V127 R130 Q131 R132 H133 N139 L140 V141 V143 P144 S145 F146 M147 R149 R168 E169 G170 R171 T172 K173 R174 N176
Binding residue
(residue number reindexed from 1)
G1 K2 T3 Y4 N6 T7 S8 K9 T10 T13 R15 R16 P17 Y18 K36 N37 K38 R39 R43 F70 E71 A74 R78 N119 S120 H123 R125 V126 R129 Q130 R131 H132 N138 L139 V140 V142 P143 S144 F145 M146 R148 R167 E168 G169 R170 T171 K172 R173 N175
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:0043226 organelle
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4bts, PDBe:4bts, PDBj:4bts
PDBsum4bts
PubMed23851459
UniProtE6PBS7

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