Structure of PDB 5aj0 Chain AC Binding Site BS01
Receptor Information
>5aj0 Chain AC (length=363) Species:
9606
(Homo sapiens) [
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CARPLISVYSEKGESSGKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPY
AVSELAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMF
APTKTWRRWHRRVNTTQKRYAICSALAASALPALVMSKGHRIEEVPELPL
VVEDKVEGYKKTKEAVLLLKKLKAWNDIKKVYASQRMRAGKGKMRNRRRI
QRRGPCIIYNEDNGIIKAFRNIPGITLLNVSKLNILKLAPGGHVGRFCIW
TESAFRKLDELYGTWRKAASLKSNYNLPMHKMINTDLSRILKSPEIQRAL
RAPRKKIHRRVLKKNPLKNLRIMLKLNPYAKTMRRNTILRQARNHKLRVD
KAAAAAAALQAKS
Ligand information
>5aj0 Chain A3 (length=157) [
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cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
cgaacgcacuugcggccccggguuccucccggggcuacgccugucugagc
gucgcuu
.........................................<<<<<<.<<
.....>>>.....(.<<<......>>.............>>>..)...>>
>....<<....>><<<<<<<<.......>>>>>>>>..............
.......
Receptor-Ligand Complex Structure
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PDB
5aj0
Structural Snapshots of Actively Translating Human Ribosomes
Resolution
3.5 Å
Binding residue
(original residue number in PDB)
P51 Y52 V54 E56 T107 K195 M196
Binding residue
(residue number reindexed from 1)
P49 Y50 V52 E54 T105 K193 M194
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003723
RNA binding
GO:0003735
structural constituent of ribosome
GO:0005515
protein binding
Biological Process
GO:0002181
cytoplasmic translation
GO:0006412
translation
Cellular Component
GO:0005634
nucleus
GO:0005730
nucleolus
GO:0005737
cytoplasm
GO:0005791
rough endoplasmic reticulum
GO:0005829
cytosol
GO:0005840
ribosome
GO:0005925
focal adhesion
GO:0016020
membrane
GO:0022625
cytosolic large ribosomal subunit
GO:0022626
cytosolic ribosome
GO:0070062
extracellular exosome
GO:1990904
ribonucleoprotein complex
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:5aj0
,
PDBe:5aj0
,
PDBj:5aj0
PDBsum
5aj0
PubMed
25957688
UniProt
P36578
|RL4_HUMAN Large ribosomal subunit protein uL4 (Gene Name=RPL4)
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