Structure of PDB 4bts Chain AC Binding Site BS01

Receptor Information
>4bts Chain AC (length=228) Species: 5911 (Tetrahymena thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TTRAINKKKKFVADGVFNAELHSFFSKSLQDAGYAGIEVRRTPTKTEIRI
KATKPQQVIGVEGKKHKELTQFLQKRFGYSDDQIQIWAEPIKFKGLCASA
QVEAMNYKLLKDVPVRLAANYIIKSVIQDGAKGCEIIISGKLKQQRAKTM
KFKQGYMICTGQPKNDYIDVAVRHVFFKQGIMGVKVKIMLPYEPNPAKKF
GVKTPIPDNVIIHPPKQITDDKEIRTAV
Ligand information
>4bts Chain AA (length=1717) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaccugguugauccugccaguuacauaugcuugucuuaaauauuaaccca
ugcaugugccaguucaguauugaacagcgaaacugcgaauggcucauuaa
aacaguuauaguuuauuugauaauuaaagauuacauggauaaccgagcua
auuguugggcuaauacaugcuuaaaauuccguguccugcgaccggaacgu
auuuauuagauauuagaccaaucgcagcaaugugauugagaugaaucaaa
guaacugaucggaucgagguuuaccucgauaaaucaucuaaguuucugcc
cuaucagcucucgaugguaguguauuggacuaccauggcagucacgggua
acggagaauuaggguucgauuccggagaaggagccugagaaacggcuacu
acaacuacgguucggcagcagggaagaaaauuggccaauccuaauucagg
gagccagugacaagaaauagcaagcugggaaacuuacguuucuacggcau
ugaaaugagaacaguguaaaucucuuagcgaggaacaauuggagggcaag
ucauggugccagcagccgcgguaauuccagcuccaauagcguauauuaaa
guuguugcaguuaaaaagcucguaguugaacuucuguucagguucauuuc
gauucgucgugugaaacuggacauacguuugcguaaacauuuuacuguga
aaaaauuagaguguuccaggcagguuuuagcccgaauacauuagcaugga
auaauggaauaggacuaaguccauuuuauugguucuuggauuugguaaug
auuaauagggacaguugggggcauuaguauuuaauagucagaggugaaau
ucuuggauuuauuaaggacuaacuaaugcgaaagcauuugccaaagaugu
uuucauuaaucaagaacgaaaguuaggggaucaaagacgaucagauaccg
ucguagucuuaacuauaaacuauaccgacucgggaucggcuggaauaaau
guccagucggcaccguaugagaaaucaaagucuuuggguucugggggaag
uaugguacgcaagucugaaacuuaaaggaauugacggaacagcacaccag
aaguggaaccugcggcuuaauuugacucaacacggggaaacucacgagcg
caagacagagaagggauugacagauugagagcucuuucuugauucuuugg
gugguggugcauggccguucuuaguugguggagugauuugucugguuaau
uccguuaacgaacgagaccuuaaccugcuaacuagucugcuuguaaauaa
cagguuguacuucuuagagggacuauugugcaauaagccaauggaaguuu
aaggcaauaacaggucugugaugccccuagacgugcucggccgcacgcgc
guuacaaugacuggcgcaaaaaguauuuccuguccugggaagguacgggu
aaucuuauuaauaccagucguguuagggauaguucuuuggaauuguggau
cuugaacgaggaauuucuaguaagugcaagucaucagcuugcguugauua
ugucccugccguuuguacacaccgcccgucgcuuguaguaacgaaugguc
uggugaaccuucuggacugcgacagcaauguugcggaaaaauaaguaaac
ccuaccauuuggaacaacaagaagucguaacaagguaucuguaggugaac
cugcagauggaucauua
...<<<<<.{.[[[[>>>>><.<.<<<<<<...<<<<.........<<<.
<<<..<<....<<...<<........>>...>>.>>......<<..<...
..<<<..<<..<<....<<<<..............<<.....<<.<<<..
...>>>.>>......>>.........<<<<<.<<<....>>>>>>>>.<.
..<<<<<........((((((..<<<....>>>......<......>..>
>>>>.....>...<<<<<<....>>>>>>...>>>>...>>>>..>>>.<
<<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>>..
.<<<<<<<<....>>>>...>>>>>>>.<<.<<<..........>>>.>>
..<<<....>>>.....>>>>>>.........<<<....<<<.....>>>
..>>>......>>>>.....<<<<<<<.<.<<<....>>>>...>>>>.>
>>..........<<.........>>.............<<<<<((.....
...<<<.....<<..))>>.......>>>..>>>>>..>>>>>>.>.>..
.......<<<[[.....<.<<...<<<.<<....<<<<<<<.<<<<<..<
<<<..>>>>.>>>>>.>>>>>>>...<<<<<..>>>>>...<<<<<<<<.
......<<...<.......>..<<<....>>>....>>......>>>>>.
.>>>.........<<<<<<<<<<.....))))))..>>>>>>>>>>....
.>>....<<<<<<.<<...<<<<..<<..<<<<<<<<...<<<......>
>>......>>>>>>>>..>>.......<<....>>...>>>>...>>>>>
.>>>...>>>...>>.>...<<<<<<<<...<...<<<<.........>>
>>...>>>>>>>>>.........<<<.<<.<<<..<<<<<<<<<......
.>>>>>>>>>..>>>...<<..]]>>...>>.....>>>.>>>.<<<...
...<<.<<....>>>>....>>>..]]]].}<<<<<.<<<.<<<.<<.<<
<<<<..<<<.<<<<<.......<<........>>..........<<<<<<
<....<<<<<<.......<<.<<<........>>>.>>.....>>>>>>.
..<<.<<<..<<<<<<<<<....<<<.<<<<<....>>>...<<<.....
.>>>...>>.>>>....<<<<<.<<..<<<<..<<<..<<<<<<.....>
>>>>>...>>>..>>>>.>>....<<<<.<<.....>>>>>>.......>
>>>>....>>>.>>>...>.>>>>>>>.....>>>>>>>....>.>>>>.
>>>.....<<<<<<.......<<.....<<<<<<<<....>>>.>>>>>.
...>>........>>>>>>...........<<.<<<..........>>>.
>>..........>>>>>>....<<<<<<<<.......>>>>>>>>.....
.>>...>>>.>>>>>>.>>....<..<<.<.<<<<<.<<..<<<<<<<<.
.<<<..<<.<..<...<<<<<<<<....>>>>>>>>...>..>.>>..>>
>..>>>>>>>>..>>.>>>>>..>.>>...>.....<<<<<<<<<....>
>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4bts The crystal structure of the eukaryotic 40S ribosomal subunit in complex with eIF1 and eIF1A.
Resolution3.703 Å
Binding residue
(original residue number in PDB)
R6 A7 I8 N9 K10 K11 K12 K30 D115 S142 G143 K144 Q147 Q148 R149 A150 K154 Y159 M160 C162 T163 G164 Q165 P166 K167 H177 F179 K181 Q182 G183 I184 P210 D211
Binding residue
(residue number reindexed from 1)
R3 A4 I5 N6 K7 K8 K9 K27 D112 S139 G140 K141 Q144 Q145 R146 A147 K151 Y156 M157 C159 T160 G161 Q162 P163 K164 H174 F176 K178 Q179 G180 I181 P207 D208
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4bts, PDBe:4bts, PDBj:4bts
PDBsum4bts
PubMed23851459
UniProtE6PBS1

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